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Published in Biomaterials (01.03.2020)
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Gene Expression by Mouse Inner Ear Hair Cells during Development
Scheffer, Déborah I, Shen, Jun, Corey, David P, Chen, Zheng-Yi
Published in The Journal of neuroscience (22.04.2015)
Published in The Journal of neuroscience (22.04.2015)
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AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial
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Shu, Yilai, Li, Wenyan, Huang, Mingqian, Quan, Yi-Zhou, Scheffer, Deborah, Tian, Chunjie, Tao, Yong, Liu, Xuezhong, Hochedlinger, Konrad, Indzhykulian, Artur A., Wang, Zhengmin, Li, Huawei, Chen, Zheng-Yi
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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
Zuris, John A, Thompson, David B, Shu, Yilai, Guilinger, John P, Bessen, Jeffrey L, Hu, Johnny H, Maeder, Morgan L, Joung, J Keith, Chen, Zheng-Yi, Liu, David R
Published in Nature biotechnology (01.01.2015)
Published in Nature biotechnology (01.01.2015)
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Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
Gao, Xue, Tao, Yong, Lamas, Veronica, Huang, Mingqian, Yeh, Wei-Hsi, Pan, Bifeng, Hu, Yu-Juan, Hu, Johnny H., Thompson, David B., Shu, Yilai, Li, Yamin, Wang, Hongyang, Yang, Shiming, Xu, Qiaobing, Polley, Daniel B., Liberman, M. Charles, Kong, Wei-Jia, Holt, Jeffrey R., Chen, Zheng-Yi, Liu, David R.
Published in Nature (London) (11.01.2018)
Published in Nature (London) (11.01.2018)
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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway
Li, Wenyan, Wu, Jingfang, Yang, Jianming, Sun, Shan, Chai, Renjie, Chen, Zheng-Yi, Li, Huawei
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2015)
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Delivery of Adeno-Associated Virus Vectors in Adult Mammalian Inner-Ear Cell Subtypes Without Auditory Dysfunction
Tao, Yong, Huang, Mingqian, Shu, Yilai, Ruprecht, Adam, Wang, Hongyang, Tang, Yong, Vandenberghe, Luk H, Wang, Qiuju, Gao, Guangping, Kong, Wei-Jia, Chen, Zheng-Yi
Published in Human gene therapy (01.04.2018)
Published in Human gene therapy (01.04.2018)
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Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo
Tao, Yong, Lamas, Veronica, Du, Wan, Zhu, Wenliang, Li, Yiran, Whittaker, Madelynn N., Zuris, John A., Thompson, David B., Rameshbabu, Arun Prabhu, Shu, Yilai, Gao, Xue, Hu, Johnny H., Pei, Charles, Kong, Wei-Jia, Liu, Xuezhong, Wu, Hao, Kleinstiver, Benjamin P., Liu, David R., Chen, Zheng-Yi
Published in Nature communications (15.08.2023)
Published in Nature communications (15.08.2023)
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Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss
Cui, Chong, Wang, Daqi, Huang, Bowei, Wang, Fang, Chen, Yuxin, Lv, Jun, Zhang, Luping, Han, Lei, Liu, Dong, Chen, Zheng-Yi, Li, Geng-Lin, Li, Huawei, Shu, Yilai
Published in Molecular therapy. Nucleic acids (13.09.2022)
Published in Molecular therapy. Nucleic acids (13.09.2022)
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Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis
Hai, Tang, Guo, Weiwei, Yao, Jing, Cao, Chunwei, Luo, Ailing, Qi, Meng, Wang, Xianlong, Wang, Xiao, Huang, Jiaojiao, Zhang, Ying, Zhang, Hongyong, Wang, Dayu, Shang, Haitao, Hong, Qianlong, Zhang, Rui, Jia, Qitao, Zheng, Qiantao, Qin, Guosong, Li, Yongshun, Zhang, Tao, Jin, Weiwu, Chen, Zheng-Yi, Wang, Hongmei, Zhou, Qi, Meng, Anming, Wei, Hong, Yang, Shiming, Zhao, Jianguo
Published in Human genetics (01.11.2017)
Published in Human genetics (01.11.2017)
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A potential ferromagnetic lanthanide‒transition heterometallic molecular‒based bacteriostatic agent
Ren, Jing, Wei, Xiao−Qing, Xu, Run−Sheng, Chen, Zheng−Yi, Wang, Jin, Wang, Miao, Sun, Tong−Ming, Wang, Minmin, Tang, Yan−Feng
Published in Journal of molecular structure (05.04.2021)
Published in Journal of molecular structure (05.04.2021)
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In Vivo Assessment of Potential Therapeutic Approaches for USH2A-Associated Diseases
Pendse, Nachiket D, Lamas, Veronica, Pawlyk, Basil S, Maeder, Morgan L, Chen, Zheng-Yi, Pierce, Eric A, Liu, Qin
Published in Advances in experimental medicine and biology (01.01.2019)
Published in Advances in experimental medicine and biology (01.01.2019)
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Generation and Genetic Correction of USH2A c.2299delG Mutation in Patient-Derived Induced Pluripotent Stem Cells
Liu, Xuezhong, Lillywhite, Justin, Zhu, Wenliang, Huang, Zaohua, Clark, Anna M, Gosstola, Nicholas, Maguire, Colin T, Dykxhoorn, Derek, Chen, Zheng-Yi, Yang, Jun
Published in Genes (25.05.2021)
Published in Genes (25.05.2021)
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Mutation of the ATP-gated P2X₂ receptor leads to progressive hearing loss and increased susceptibility to noise
Yan, Denise, Zhu, Yan, Walsh, Tom, Xie, Dinghua, Yuan, Huijun, Sirmaci, Asli, Fujikawa, Taro, Wong, Ann Chi Yan, Loh, Tze L., Du, Lilin, Grati, M'hamed, Vlajkovic, Srdjan M., Blanton, Susan, Ryan, Allen F., Chen, Zheng-Yi, Thorne, Peter R., Kachar, Bechara, Tekin, Mustafa, Zhao, Hong-Bo, Housley, Gary D., King, Mary-Claire, Liu, Xue Z.
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Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2013)
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Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration
Lee, Sang Goo, Huang, Mingqian, Obholzer, Nikolaus D, Sun, Shan, Li, Wenyan, Petrillo, Marco, Dai, Pu, Zhou, Yi, Cotanche, Douglas A, Megason, Sean G, Li, Huawei, Chen, Zheng-Yi
Published in PloS one (28.06.2016)
Published in PloS one (28.06.2016)
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Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing
Zheng, Ziwen, Li, Guo, Cui, Chong, Wang, Fang, Wang, Xiaohan, Xu, Zhijiao, Guo, Huiping, Chen, Yuxin, Tang, Honghai, Wang, Daqi, Huang, Mingqian, Chen, Zheng-Yi, Huang, Xingxu, Li, Huawei, Li, Geng-Lin, Hu, Xiaoxiang, Shu, Yilai
Published in Signal transduction and targeted therapy (14.03.2022)
Published in Signal transduction and targeted therapy (14.03.2022)
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Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art
Nourbakhsh, Aida, Colbert, Brett M., Nisenbaum, Eric, El-Amraoui, Aziz, Dykxhoorn, Derek M., Koehler, Karl Russell, Chen, Zheng-yi, Liu, Xue Z.
Published in Journal of the Association for Research in Otolaryngology (01.04.2021)
Published in Journal of the Association for Research in Otolaryngology (01.04.2021)
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