Design and Synthesis of EZH2-Based PROTACs to Degrade the PRC2 Complex for Targeting the Noncatalytic Activity of EZH2
Liu, Zhihao, Hu, Xi, Wang, Qiwei, Wu, Xiuli, Zhang, Qiangsheng, Wei, Wei, Su, Xingping, He, Hualong, Zhou, Shuyan, Hu, Rong, Ye, Tinghong, Zhu, Yongxia, Wang, Ningyu, Yu, Luoting
Published in Journal of medicinal chemistry (11.03.2021)
Published in Journal of medicinal chemistry (11.03.2021)
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Journal Article
Covalent Construction of Sustainable Hybrid UiO-66-NH2@Tb-CP Material for Selective Removal of Dyes and Detection of Metal Ions
Zhang, Qiangsheng, Jiang, Xue, Kirillov, Alexander M, Zhang, Yanwen, Hu, Mingyang, Liu, Wei, Yang, Lizi, Fang, Ran, Liu, Weisheng
Published in ACS sustainable chemistry & engineering (04.02.2019)
Published in ACS sustainable chemistry & engineering (04.02.2019)
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Journal Article
Covalent inhibitors of EZH2: Design, synthesis and evaluation
Zhang, Qiangsheng, Chen, Xinyi, Hu, Xi, Duan, Xianjie, Wan, Guoquan, Li, Lu, Feng, Qiang, Zhang, Yiqian, Wang, Ningyu, Yu, Luoting
Published in Biomedicine & pharmacotherapy (01.03.2022)
Published in Biomedicine & pharmacotherapy (01.03.2022)
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Journal Article
A Facile Total Synthesis of Kilogram-Scale Production of SKLB1039: A Novel and Selective Hexahydroisoquinolin-Containing EZH2 Inhibitor
Feng, Qiang, Zhang, Qiangsheng, He, Hualong, Zhang, Lidan, Chang, Bo, Yu, Luoting, Zhang, Xiaoling
Published in Current organic synthesis (01.08.2022)
Published in Current organic synthesis (01.08.2022)
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Journal Article
Multifunctional Ln–MOF Luminescent Probe for Efficient Sensing of Fe3+, Ce3+, and Acetone
Zhang, Qiangsheng, Wang, Jun, Kirillov, Alexander M, Dou, Wei, Xu, Cong, Xu, Cailing, Yang, Lizi, Fang, Ran, Liu, Weisheng
Published in ACS applied materials & interfaces (18.07.2018)
Published in ACS applied materials & interfaces (18.07.2018)
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Journal Article
Covalent inhibitors meet epigenetics: New opportunities
Feng, Qiang, Yu, Luoting, Li, Lu, Zhang, Qiangsheng
Published in European journal of medicinal chemistry (15.12.2024)
Published in European journal of medicinal chemistry (15.12.2024)
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Journal Article
Discovery of novel G9a/GLP covalent inhibitors for the treatment of triple-negative breast cancer
Zhang, Qiangsheng, Chang, Bo, Feng, Qiang, Li, Lu
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Journal Article
The molecular mechanisms of MLKL-dependent and MLKL-independent necrosis
Li, Lu, Tong, An, Zhang, Qiangsheng, Wei, Yuquan, Wei, Xiawei
Published in Journal of molecular cell biology (10.04.2021)
Published in Journal of molecular cell biology (10.04.2021)
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Journal Article
PERFORMANCE EVALUATION TECHNIQUES FOR THE NUCLEAR GRADE MAIN FEED-WATER CONTROL VALVE
LIU QingMin, GAO ZhaoJie, LIN Feng, ZHANG QiangSheng, WU Xin
Published in Ji xie qiang du (15.10.2015)
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Published in Ji xie qiang du (15.10.2015)
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Design, synthesis and evaluation of antitumor activity of selective PRMT6 inhibitors
Zhang, Qiangsheng, Cao, Jiaying, Zhang, Yiqian, Bi, Zhenfei, Feng, Qiang, Yu, Luoting, Li, Lu
Published in European journal of medicinal chemistry (05.02.2023)
Published in European journal of medicinal chemistry (05.02.2023)
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Journal Article
Pharmacological inhibition of EZH2 using a covalent inhibitor suppresses human ovarian cancer cell migration and invasion
Shi, Lihong, Zhang, Qiangsheng, Zhu, Shirui, Tang, Qing, Chen, Xin, Lan, Rui, Wang, Ningyu, Zhu, Yongxia
Published in Molecular and cellular biochemistry (01.04.2024)
Published in Molecular and cellular biochemistry (01.04.2024)
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Journal Article
Pharmacological inhibition of EZH2 by ZLD1039 suppresses tumor growth and pulmonary metastasis in melanoma cells in vitro and in vivo
Zhu, Yongxia, Zhang, Lidan, Song, Xuejiao, Zhang, Qiangsheng, Wang, Ting, Xiao, Hongtao, Yu, Luoting
Published in Biochemical pharmacology (01.04.2023)
Published in Biochemical pharmacology (01.04.2023)
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Journal Article
A TICT-AIE activated dual-channel fluorescence-on probe to reveal the dynamics mechanosensing of lipid droplets during ferroptosis
Yu, Ao, Zhang, Wei, Zhang, Qiangsheng, Yang, Kunlong, Liu, Xiongbo, Liu, Hongtao, Xie, Jialin, Feng, Yan, Li, Jianwei, Jia, Chunman
Published in Talanta (Oxford) (01.07.2024)
Published in Talanta (Oxford) (01.07.2024)
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Journal Article
Discovery of a Novel Covalent EZH2 Inhibitor Based on Tazemetostat Scaffold for the Treatment of Ovarian Cancer
Zhang, Qiangsheng, Chen, Xinyi, Cao, Jiaying, Yang, Wan, Wan, Guoquan, Feng, Qiang, Zhou, Shuyan, Yang, Hongling, Wang, Ningyu, Liu, Zhihao, Xiao, Hongtao, Zhu, Yongxia, Yu, Luoting
Published in Journal of medicinal chemistry (09.02.2023)
Published in Journal of medicinal chemistry (09.02.2023)
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Journal Article
Design and Synthesis of Fibroblast Growth Factor Receptor (FGFR) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Cancer
Wan, Guoquan, Feng, Zhanzhan, Zhang, Qiangsheng, Li, Xiao, Ran, Kai, Feng, Huan, Luo, Tianwen, Zhou, Shuyan, Su, Chang, Wei, Wei, Wang, Ningyu, Gao, Chao, Zhao, Lifeng, Yu, Luoting
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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