Search Results - "ZHAN, CHANG-GUO" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

by Li, Zhe, Li, Xin, Huang, Yi-You, Wu, Yaoxing, Liu, Runduo, Zhou, Lingli, Lin, Yuxi, Wu, Deyan, Zhang, Lei, Liu, Hao, Xu, Ximing, Yu, Kunqian, Zhang, Yuxia, Cui, Jun, Zhan, Chang-Guo, Wang, Xin, Luo, Hai-Bin
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2020)

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Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine

Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine

by Zhan, Max, Hou, Shurong, Shang, Linyue, Chen, Xiabin, Zhan, Chang-Guo, Zheng, Fang
Published in Organic & biomolecular chemistry (03.05.2023)

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Clinical data mining reveals analgesic effects of lapatinib in cancer patients

Clinical data mining reveals analgesic effects of lapatinib in cancer patients

by Zhou, Shuo, Zheng, Fang, Zhan, Chang-Guo
Published in Scientific reports (11.02.2021)

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Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane

Cocaine hydrolase blocks cocaine‐induced dopamine transporter trafficking to the plasma membrane

by Deng, Jing, Kim, Kyungbo, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.01.2022)

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Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations

Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations

by Lin, Hong‐Yan, Yang, Jing‐Fang, Wang, Da‐Wei, Hao, Ge‐Fei, Dong, Jiang‐Qing, Wang, Yu‐Xia, Yang, Wen‐Chao, Wu, Jia‐Wei, Zhan, Chang‐Guo, Yang, Guang‐Fu
Published in The FEBS journal (01.03.2019)

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Recovery of dopaminergic system after cocaine exposure and impact of a long‐acting cocaine hydrolase

Recovery of dopaminergic system after cocaine exposure and impact of a long‐acting cocaine hydrolase

by Deng, Jing, Zhang, Ting, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.07.2022)

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Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene

Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene

by Zheng, Xirong, Chen, Xiabin, Zhang, Ting, Zhan, Max, Zhan, Chang-Guo, Zheng, Fang
Published in Organic & biomolecular chemistry (11.03.2020)

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DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1

DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1

by Zhou, Shuo, Zhou, Ziyuan, Ding, Kai, Yuan, Yaxia, Loftin, Charles, Zheng, Fang, Zhan, Chang-Guo
Published in Scientific reports (23.06.2020)

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Gender differences in cocaine‐induced hyperactivity and dopamine transporter trafficking to the plasma membrane

Gender differences in cocaine‐induced hyperactivity and dopamine transporter trafficking to the plasma membrane

by Deng, Jing, Zheng, Xirong, Shang, Linyue, Zhan, Chang‐Guo, Zheng, Fang
Published in Addiction biology (01.11.2022)

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Effects of Cebranopadol on Cocaine-induced Hyperactivity and Cocaine Pharmacokinetics in Rats

Effects of Cebranopadol on Cocaine-induced Hyperactivity and Cocaine Pharmacokinetics in Rats

by Wei, Huimei, Shang, Linyue, Zhan, Chang-Guo, Zheng, Fang
Published in Scientific reports (09.06.2020)

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Development of pharmacotherapies for abdominal aortic aneurysms

Development of pharmacotherapies for abdominal aortic aneurysms

by Weaver, Lauren M., Loftin, Charles D., Zhan, Chang-Guo
Published in Biomedicine & pharmacotherapy (01.09.2022)

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Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs

Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs

by Ding, Kai, Zhou, Ziyuan, Hou, Shurong, Yuan, Yaxia, Zhou, Shuo, Zheng, Xirong, Chen, Jianzhong, Loftin, Charles, Zheng, Fang, Zhan, Chang-Guo
Published in Scientific reports (26.03.2018)

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Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection

Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection

by Zheng, Fang, Lian, Elena, Ramirez, Gaby, McAlister, Carley, Zhou, Shuo, Zhang, Wen, Liu, Chunming, Perera, Rushika, Zhan, Chang-Guo
Published in PloS one (18.08.2022)

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A highly efficient cocaine-detoxifying enzyme obtained by computational design

A highly efficient cocaine-detoxifying enzyme obtained by computational design

by Zheng, Fang, Xue, Liu, Hou, Shurong, Liu, Junjun, Zhan, Max, Yang, Wenchao, Zhan, Chang-Guo
Published in Nature communications (18.03.2014)

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Catalytic Mechanism of Cytochrome P450 for 5′-Hydroxylation of Nicotine: Fundamental Reaction Pathways and Stereoselectivity

Catalytic Mechanism of Cytochrome P450 for 5′-Hydroxylation of Nicotine: Fundamental Reaction Pathways and Stereoselectivity

by Li, Dongmei, Huang, Xiaoqin, Han, Keli, Zhan, Chang-Guo
Published in Journal of the American Chemical Society (18.05.2011)

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Assessment of the performance of six indices in predicating the aromaticity of planar porphyrinoids

Assessment of the performance of six indices in predicating the aromaticity of planar porphyrinoids

by Ding, Wenjing, Zhang, Zhan, Chen, Xi, Zhan, Chang-guo
Published in Journal of molecular modeling (01.03.2023)

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Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine

Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine

by Shang, Linyue, Jin, Zhenyu, Wei, Huimei, Park, Shawn, Zhan, Chang-Guo, Zheng, Fang
Published in Scientific reports (12.01.2023)

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A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

by Zhang, Tao, Hamza, Adel, Cao, Xianhua, Wang, Bing, Yu, Shuwen, Zhan, Chang-Guo, Sun, Duxin
Published in Molecular cancer therapeutics (01.01.2008)

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Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats

Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats

by Wei, Huimei, LeSaint, Johnathan E., Jin, Zhenyu, Zhan, Chang-Guo, Zheng, Fang
Published in Scientific reports (09.01.2024)

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Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice

Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice

by Guo, Ling, Morin, Emily E, Yu, Minzhi, Mei, Ling, Fawaz, Maria V, Wang, Qian, Yuan, Yaxia, Zhan, Chang-Guo, Standiford, Theodore J, Schwendeman, Anna, Li, Xiang-An
Published in Science signaling (15.03.2022)

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