Photocontrol of Protein Activity Mediated by the Cleavage Reaction of a Split Intein
Binschik, Jens, Zettler, Joachim, Mootz, Henning D.
Published in Angewandte Chemie International Edition (28.03.2011)
Published in Angewandte Chemie International Edition (28.03.2011)
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Journal Article
Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction
Zúñiga, Luis Alejandro, Leßmann, Torben, Uppal, Karan, Bisek, Nicola, Hong, Enping, Rasmussen, Caroline E., Karlsson, Jens-Jakob, Zettler, Joachim, Holten-Andersen, Lars, Bang, Kathy, Thakar, Dhruv, Lee, Yu-Chi, Martinez, Salomon, Sabharwal, Simran Singh, Stark, Sebastian, Faltinger, Frank, Kracker, Oliver, Weisbrod, Samuel, Müller, Robin, Voigt, Tobias, Bigott, Kornelia, Tabrizifard, Mohammad, Breinholt, Vibeke Miller, Mirza, Amer M., Rosen, David B., Sprogøe, Kennett, Punnonen, Juha
Published in Cancer cell international (19.09.2022)
Published in Cancer cell international (19.09.2022)
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Journal Article
SPLICEFINDER - a fast and easy screening method for active protein trans-splicing positions
Zettler, Joachim, Eppmann, Simone, Busche, Alena, Dikovskaya, Dina, Dötsch, Volker, Mootz, Henning D, Sonntag, Tim
Published in PloS one (02.09.2013)
Published in PloS one (02.09.2013)
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Journal Article
TransCon CNP, a Sustained-Release C-Type Natriuretic Peptide Prodrug, a Potentially Safe and Efficacious New Therapeutic Modality for the Treatment of Comorbidities Associated with Fibroblast Growth Factor Receptor 3-Related Skeletal Dysplasias
Breinholt, Vibeke Miller, Rasmussen, Caroline E, Mygind, Per Holse, Kjelgaard-Hansen, Mads, Faltinger, Frank, Bernhard, Ana, Zettler, Joachim, Hersel, Ulrich
Published in The Journal of pharmacology and experimental therapeutics (01.09.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2019)
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Journal Article
Design and Preclinical Development of TransCon PTH, an Investigational Sustained‐Release PTH Replacement Therapy for Hypoparathyroidism
Holten‐Andersen, Lars, Pihl, Susanne, Rasmussen, Caroline E, Zettler, Joachim, Maitro, Guillaume, Baron, Julia, Heinig, Stefan, Hoffmann, Eric, Wegge, Thomas, Krusch, Mathias, Faltinger, Frank, Killian, Steffen, Sprogoe, Kennett, Karpf, David B, Breinholt, Vibeke Miller, Cleemann, Felix
Published in Journal of bone and mineral research (01.11.2019)
Published in Journal of bone and mineral research (01.11.2019)
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Journal Article
TransCon IL-2 β/γ, a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 analog, demonstrates improved pharmacokinetics and profound expansion of cytotoxic immune cells in non-human primates
Rosen, David, Månsson Kvarnhammar, Anne, Olling, Janne Damm, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Kurpiers, Thomas, Zettler, Joachim, Runz, Josefine, Faltinger, Frank, Viet, Laura, Krusch, Mathias, Schnabel, Meike, Reich, Diana, Glock, Philipp, Singel, Stina Mui, Sprogøe, Kennett, Abel, Kristin Laura, Breinholt, Vibeke Miller, Punnonen, Juha
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Abstract 4507: TransConTM IL-2 β/γ: a novel long-acting prodrug of receptor-biased IL-2 designed for improved pharmocokinetics and optimal activation of T cells for the treatment of cancer
Rosen, David Brian, Laufer, Burkhardt, Knappe, Thomas, Schnabel, Meike, Begaliew, Diana, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Breinholt, Vibeke, Tabrizi, Mohammad, Sprogoe, Kennett, Punnonen, Juha
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
PTH PTH PRODRUGS
CLEEMANN FELIX, WEGGE THOMAS, SPROGE KENNETT, MAITRO GUILLAUME, ZETTLER JOACHIM, KRUSCH MATHIAS
Year of Publication 31.01.2023
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Year of Publication 31.01.2023
Patent
hGH NOVEL POLYMERIC HGH PRODRUGS
WEGGE THOMAS, EXNER EVELYN, KURPIERS THOMAS, RASMUSSEN GRETHE NRSKOV, SCHUBERT NINA, SPLANEMANN ANNA, ZETTLER JOACHIM, JENSEN STEEN, HERMANN ALINA, RAU HARALD, LESSMANN TORBEN
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
Patent
PTH PTH PRODRUGS
SPROGØE KENNETT, CLEEMANN FELIX, WEGGE THOMAS, MAITRO GUILLAUME, ZETTLER JOACHIM, KRUSCH MATHIAS
Year of Publication 06.12.2021
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Year of Publication 06.12.2021
Patent
TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer
Rosen, David B, Kvarnhammar, Anne Månsson, Laufer, Burkhardt, Knappe, Thomas, Karlsson, Jens Jakob, Hong, Enping, Lee, Yu-Chi, Thakar, Dhruv, Zúñiga, Luis Alejandro, Bang, Kathy, Sabharwal, Simran Singh, Uppal, Karan, Olling, Janne Damm, Kjaergaard, Kristian, Kurpiers, Thomas, Schnabel, Meike, Reich, Diana, Glock, Philipp, Zettler, Joachim, Krusch, Mathias, Bernhard, Ana, Heinig, Stefan, Konjik, Valentino, Wegge, Thomas, Hehn, Yvonne, Killian, Steffen, Viet, Laura, Runz, Josefine, Faltinger, Frank, Tabrizi, Mohammad, Abel, Kristin Laura, Breinholt, Vibeke Miller, Singel, Stina M, Sprogøe, Kennett, Punnonen, Juha
Published in Journal for immunotherapy of cancer (01.07.2022)
Published in Journal for immunotherapy of cancer (01.07.2022)
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Journal Article
PTH 프로드럭
SPROGØE KENNETT, CLEEMANN FELIX, WEGGE THOMAS, MAITRO GUILLAUME, ZETTLER JOACHIM, KRUSCH MATHIAS
Year of Publication 30.10.2018
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Year of Publication 30.10.2018
Patent
hGH NOVEL POLYMERIC HGH PRODRUGS
WEGGE THOMAS, EXNER EVELYN, KURPIERS THOMAS, SCHUBERT NINA, SPLANEMANN ANNA, RASMUSSEN GRETHE NØRSKOV, ZETTLER JOACHIM, JENSEN STEEN, HERMANN ALINA, RAU HARALD, LESSMANN TORBEN
Year of Publication 19.07.2017
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Year of Publication 19.07.2017
Patent
SUSTAINED RELEASE COMPOSITION OF PROSTACYCLIN
WEGGE THOMAS, KEIL OLIVER, ZETTLER JOACHIM, SPROG E KENNETT, RAU HARALD, HERSEL ULRICH
Year of Publication 02.07.2014
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Year of Publication 02.07.2014
Patent
Innovative manufacturing of complex Ti sheet components (INMA)
Penalva Oscoz, Mariluz, Zettler, Joachim, Papadopoulos, Michael P
Published in International journal of structural integrity (22.11.2011)
Published in International journal of structural integrity (22.11.2011)
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Journal Article
CARRIER-LINKED TREPROSTINIL PRODRUGS
BISEK NICOLA, WEGGE THOMAS, KEIL OLIVER, MAITRO GUILLAUME, ZETTLER JOACHIM, SPROG E KENNETT, HERSEL ULRICH, RAU HARALD, LESSMANN TORBEN
Year of Publication 10.06.2014
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Year of Publication 10.06.2014
Patent
MODIFIED HYDROGELS
LAUFER, Burkhardt, REIMANN, Romy, HERSEL, Ulrich, RAU, Harald, ZETTLER, Joachim
Year of Publication 03.05.2023
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Year of Publication 03.05.2023
Patent