Search Results - "ZENG, Binqi" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration

Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration

by Palanki, Moorthy S. S, Akiyama, Hideo, Campochiaro, Peter, Cao, Jianguo, Chow, Chun P, Dellamary, Luis, Doukas, John, Fine, Richard, Gritzen, Colleen, Hood, John D, Hu, Steven, Kachi, Shu, Kang, Xinshan, Klebansky, Boris, Kousba, Ahmed, Lohse, Dan, Mak, Chi Ching, Martin, Michael, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Umeda, Naoyasu, Yee, Shiyin, Yokoi, Katsutoshi, Zeng, Binqi, Zhu, Hong, Noronha, Glenn
Published in Journal of medicinal chemistry (27.03.2008)

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Journal Article

Inhibitors of ABL and the ABL-T315I mutation

Inhibitors of ABL and the ABL-T315I mutation

by Noronha, Glenn, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Fine, Richard M, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andre, Palanki, Moorthy S S, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi
Published in Current topics in medicinal chemistry (01.07.2008)

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Journal Article

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

by Noronha, Glenn, Barrett, Kathy, Boccia, Antonio, Brodhag, Tessa, Cao, Jianguo, Chow, Chun P., Dneprovskaia, Elena, Doukas, John, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Gu, Hong, Hanna, Ehab, Hood, John D., Hu, Steven, Kang, Xinshan, Key, Jann, Klebansky, Boris, Kousba, Ahmed, Li, Ge, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Shi, Feng, Soll, Richard, Splittgerber, Ute, Stoughton, Silva, Tang, Suhan, Yee, Shiyin, Zeng, Binqi, Zhao, Ningning, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.02.2007)

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Journal Article

The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes

The design and preliminary structure–activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes

by Cao, Jianguo, Fine, Richard, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Noronha, Glenn, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Zeng, Binqi, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.11.2007)

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Journal Article

Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors

Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors

by Noronha, Glenn, Barrett, Kathy, Cao, Jianguo, Dneprovskaia, Elena, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Li, G., Liao, W., Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Splittgerber, Ute, Wrasidlo, Wolfgang, Zeng, Binqi, Zhao, Ningning, Zhou, Y.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)

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Journal Article

Metabolism and pharmacokinetics of a novel Src kinase inhibitor TG100435 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-amine) and its active N-oxide metabolite TG100855 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-{4-[2-(1 -oxy-pyrrolidin-1 -yl)-ethoxy]-phenyl}-amine)

Metabolism and pharmacokinetics of a novel Src kinase inhibitor TG100435 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-amine) and its active N-oxide metabolite TG100855 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-{4-[2-(1 -oxy-pyrrolidin-1 -yl)-ethoxy]-phenyl}-amine)

by HU, Steven X, SOIL, Richard, TABAK, Arek, HOOD, John, DOUKAS, John, NORONHA, Glenn, MARTIN, Michael, SHIYIN YEE, LOHSE, Daniel L, KOUSBA, Ahmed, BINQI ZENG, XIYUN YU, MCPHERSON, Andrew, RENICK, Joel, CAO, Jianguo
Published in Drug metabolism and disposition (01.06.2007)

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Journal Article

Metabolism and Pharmacokinetics of a Novel Src Kinase Inhibitor TG100435 ([7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) and Its Active N-Oxide Metabolite TG100855 ([7-(2,6-Dichloro-phenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-{4-[2-(1-oxy-pyrrolidin-1-yl)-ethoxy]-phenyl}-amine)

Metabolism and Pharmacokinetics of a Novel Src Kinase Inhibitor TG100435 ([7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) and Its Active N-Oxide Metabolite TG100855 ([7-(2,6-Dichloro-phenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-{4-[2-(1-oxy-pyrrolidin-1-yl)-ethoxy]-phenyl}-amine)

by Hu, Steven X, Soll, Richard, Yee, Shiyin, Lohse, Daniel L, Kousba, Ahmed, Zeng, Binqi, Yu, Xiyun, McPherson, Andrew, Renick, Joel, Cao, Jianguo, Tabak, Arek, Hood, John, Doukas, John, Noronha, Glenn, Martin, Michael
Published in Drug metabolism and disposition (01.06.2007)

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Journal Article

H3NI: Non-target-specific node injection attacks on hypergraph neural networks via genetic algorithm

H3NI: Non-target-specific node injection attacks on hypergraph neural networks via genetic algorithm

by Shi, Heyuan, Zeng, Binqi, Yu, Ruishi, Yang, Yulin, Zouxia, Zijian, Hu, Chao, Ronghua, Shi
Published in Neurocomputing (Amsterdam) (01.10.2024)

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Journal Article

Human-Imperceptible Retrieval Poisoning Attacks in LLM-Powered Applications

Human-Imperceptible Retrieval Poisoning Attacks in LLM-Powered Applications

by Zhang, Quan, Zeng, Binqi, Zhou, Chijin, Go, Gwihwan, Shi, Heyuan, Jiang, Yu
Year of Publication 26.04.2024

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Journal Article

HyperAttack: Multi-Gradient-Guided White-box Adversarial Structure Attack of Hypergraph Neural Networks

HyperAttack: Multi-Gradient-Guided White-box Adversarial Structure Attack of Hypergraph Neural Networks

by Hu, Chao, Yu, Ruishi, Zeng, Binqi, Zhan, Yu, Fu, Ying, Zhang, Quan, Liu, Rongkai, Shi, Heyuan
Year of Publication 23.02.2023

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Journal Article

BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

by NORONHA GLENN, SOLL RICHARD M, MC PHERSON ANDREW, CAO JIANGUO, ZENG BINQI, RENICK JOEL, HOOD JOHN, MAK CHI CHING, LOHSE DANIEL, PATHAK VED
Year of Publication 10.09.2013

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Patent

Development of novel benzotriazines for drug discovery

Development of novel benzotriazines for drug discovery

by Palanki, Moorthy Ss, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Mak, Chi Ching, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi, Noronha, Glenn
Published in Expert opinion on drug discovery (01.01.2009)

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Journal Article

In Vitro and In Vivo Inhibition of the T315I Mutant BCR/ABL Kinase

In Vitro and In Vivo Inhibition of the T315I Mutant BCR/ABL Kinase

by Zhu, Hong, Hanna, Ehab, Lohse, Dan, Stoughton, Silva, Tam, Betty, Barrett, Kathy, Noronha, Glenn, Dneprovskaia, Elena, Cao, Jon, Chow, Chun, Hwang, Linda, Mak, Chiching, McPherson, Andy, Palanki, Moorthy, Pathak, Ved P., Renick, Joe, Soll, Richard, Zeng, Binqi, Hood, John
Published in Blood (16.11.2006)

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Journal Article

A Phosphinate Inhibitor of the meso-Diaminopimelic Acid-Adding Enzyme (MurE) of Peptidoglycan Biosynthesis

A Phosphinate Inhibitor of the meso-Diaminopimelic Acid-Adding Enzyme (MurE) of Peptidoglycan Biosynthesis

by Zeng, Binqi, Wong, Kenny K, Pompliano, David L, Reddy, Sreelatha, Tanner, Martin E
Published in Journal of organic chemistry (25.12.1998)

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Journal Article

HyperAttack: Multi-Gradient-Guided White-box Adversarial Structure Attack of Hypergraph Neural Networks

HyperAttack: Multi-Gradient-Guided White-box Adversarial Structure Attack of Hypergraph Neural Networks

by Hu, Chao, Yu, Ruishi, Zeng, Binqi, Yu, Zhan, Fu, Ying, Zhang, Quan, Liu, Rongkai, Shi, Heyuan
Published in arXiv.org (24.02.2023)

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Paper

Molecular recognition-controlled membrane disruption by a bis(crown ether) bola-amphiphile

Molecular recognition-controlled membrane disruption by a bis(crown ether) bola-amphiphile

by Fyles, TM, Zeng, BQ
Published in Chemical communications (Cambridge, England) (1996)

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Journal Article

Pneumatic compression device with integrated pump

Pneumatic compression device with integrated pump

by SILVA GARCIES WENDY AGUSTIN, WEBB WILLIAM, SANCHI SOLANA, JOSE, CARBERRY, BRIAN, ZENG, BINQI
Year of Publication 03.10.2023

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Patent

Genetic algorithm-based hypergraph neural network adversarial sample generation method

Genetic algorithm-based hypergraph neural network adversarial sample generation method

by LIU RONGKAI, HU CHAO, LIU SHUNING, SHI HEYUAN, ZENG BINQI, LUO JING, YU RUISHI
Year of Publication 08.12.2023

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Patent

BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES

by CAO, JIANGUO, HOOD, JOHN, MC PHERSON, ANDREW, PATHAK, VED P, LOHSE, DANIEL, MAK, CHI CHING, NORONHA, GLENN, RENICK, JOEL, SOLL, RICHARD M, ZENG, BINQI
Year of Publication 14.08.2018

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Patent

Manufacturing process of multi-layer balance-to-unbalance converter

Manufacturing process of multi-layer balance-to-unbalance converter

by LIU GUOFENG, ZENG BINQI
Year of Publication 17.04.2013

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Patent

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