Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin
Diep, Binh An, Le, Vien T M, Visram, Zehra C, Rouha, Harald, Stulik, Lukas, Dip, Etyene Castro, Nagy, Gábor, Nagy, Eszter
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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Journal Article
Phage activity against Staphylococcus aureus is impaired in plasma and synovial fluid
Mutti, Michele, Moreno, David Sáez, Restrepo-Córdoba, Marcela, Visram, Zehra, Resch, Grégory, Corsini, Lorenzo
Published in Scientific reports (24.10.2023)
Published in Scientific reports (24.10.2023)
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Journal Article
Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody
Rouha, Harald, Badarau, Adriana, Visram, Zehra C, Battles, Michael B, Prinz, Bianka, Magyarics, Zoltán, Nagy, Gábor, Mirkina, Irina, Stulik, Lukas, Zerbs, Manuel, Jägerhofer, Michaela, Maierhofer, Barbara, Teubenbacher, Astrid, Dolezilkova, Ivana, Gross, Karin, Banerjee, Srijib, Zauner, Gerhild, Malafa, Stefan, Zmajkovic, Jakub, Maier, Sabine, Mabry, Robert, Krauland, Eric, Wittrup, K Dane, Gerngross, Tillman U, Nagy, Eszter
Published in mAbs (01.01.2015)
Published in mAbs (01.01.2015)
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Journal Article
Disarming Staphylococcus aureus from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies
Rouha, Harald, Weber, Susanne, Janesch, Philipp, Maierhofer, Barbara, Gross, Karin, Dolezilkova, Ivana, Mirkina, Irina, Visram, Zehra C., Malafa, Stefan, Stulik, Lukas, Badarau, Adriana, Nagy, Eszter
Published in Virulence (01.01.2018)
Published in Virulence (01.01.2018)
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Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258
Szijártó, Valéria, Guachalla, Luis M., Hartl, Katharina, Varga, Cecília, Badarau, Adriana, Mirkina, Irina, Visram, Zehra C., Stulik, Lukas, Power, Christine A., Nagy, Eszter, Nagy, Gábor
Published in Virulence (03.10.2017)
Published in Virulence (03.10.2017)
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Journal Article
Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8
Janesch, Philipp, Rouha, Harald, Weber, Susanne, Malafa, Stefan, Gross, Karin, Maierhofer, Barbara, Badarau, Adriana, Visram, Zehra C, Stulik, Lukas, Nagy, Eszter
Published in The Journal of infection (01.05.2017)
Published in The Journal of infection (01.05.2017)
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Journal Article
Bactericidal monoclonal antibodies specific to the lipopolysaccharide O antigen from multidrug-resistant Escherichia coli clone ST131-O25b:H4 elicit protection in mice
Szijártó, Valéria, Guachalla, Luis M, Visram, Zehra C, Hartl, Katharina, Varga, Cecília, Mirkina, Irina, Zmajkovic, Jakub, Badarau, Adriana, Zauner, Gerhild, Pleban, Clara, Magyarics, Zoltán, Nagy, Eszter, Nagy, Gábor
Published in Antimicrobial agents and chemotherapy (01.06.2015)
Published in Antimicrobial agents and chemotherapy (01.06.2015)
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Journal Article
ε2-Phages Are Naturally Bred and Have a Vastly Improved Host Range in Staphylococcus aureus over Wild Type Phages
Sáez Moreno, David, Visram, Zehra, Mutti, Michele, Restrepo-Córdoba, Marcela, Hartmann, Susana, Kremers, Ana Isabel, Tišáková, Lenka, Schertler, Susanne, Wittmann, Johannes, Kalali, Benham, Monecke, Stefan, Ehricht, Ralf, Resch, Grégory, Corsini, Lorenzo
Published in Pharmaceuticals (Basel, Switzerland) (02.04.2021)
Published in Pharmaceuticals (Basel, Switzerland) (02.04.2021)
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Journal Article
Natural Bred ε2-Phages Have an Improved Host Range and Virulence against Uropathogenic Escherichia coli over Their Ancestor Phages
Loose, Maria, Sáez Moreno, David, Mutti, Michele, Hitzenhammer, Eva, Visram, Zehra, Dippel, David, Schertler, Susanne, Tišáková, Lenka Podpera, Wittmann, Johannes, Corsini, Lorenzo, Wagenlehner, Florian
Published in Antibiotics (Basel) (01.11.2021)
Published in Antibiotics (Basel) (01.11.2021)
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Journal Article
Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid
Stulik, Lukas, Rouha, Harald, Labrousse, Delphine, Visram, Zehra Claire, Badarau, Adriana, Maierhofer, Barbara, Groß, Karin, Weber, Susanne, Kramarić, Miroslava Dominis, Glojnarić, Ines, Nagy, Gábor, Croisier, Delphine, Nagy, Eszter
Published in Scientific reports (29.03.2019)
Published in Scientific reports (29.03.2019)
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Journal Article
ε 2 -Phages Are Naturally Bred and Have a Vastly Improved Host Range in Staphylococcus aureus over Wild Type Phages
Sáez Moreno, David, Visram, Zehra, Mutti, Michele, Restrepo-Córdoba, Marcela, Hartmann, Susana, Kremers, Ana Isabel, Tišáková, Lenka, Schertler, Susanne, Wittmann, Johannes, Kalali, Benham, Monecke, Stefan, Ehricht, Ralf, Resch, Grégory, Corsini, Lorenzo
Published in Pharmaceuticals (Basel, Switzerland) (02.04.2021)
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Published in Pharmaceuticals (Basel, Switzerland) (02.04.2021)
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Natural Bred ε 2 -Phages Have an Improved Host Range and Virulence against Uropathogenic Escherichia coli over Their Ancestor Phages
Loose, Maria, Sáez Moreno, David, Mutti, Michele, Hitzenhammer, Eva, Visram, Zehra, Dippel, David, Schertler, Susanne, Tišáková, Lenka Podpera, Wittmann, Johannes, Corsini, Lorenzo, Wagenlehner, Florian
Published in Antibiotics (Basel) (01.11.2021)
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Published in Antibiotics (Basel) (01.11.2021)
Journal Article
Prevention of Lung Pathology and Mortality in Rabbit Staphylococcus aureus Pneumonia with Cytotoxin-Neutralizing Monoclonal IgGs that Penetrate Epithelial Lining Fluid
Stulik, Lukas, Rouha, Harald, Labrousse, Delphine, Visram, Zehra, Nagy, Gabor, Croisier, Delphine, Nagy, Eszter
Published in Open forum infectious diseases (01.10.2017)
Published in Open forum infectious diseases (01.10.2017)
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1388. Dose Discrimination for ASN100: Bridging from Rabbit Survival Data to Predicted Activity in Humans Using a Minimal Physiologically Based Pharmacokinetic (mPBPK) Model
Rubino, Christopher M, Stulik, Lukas, Rouha, Harald, Visram, Zehra, Badarau, Adriana, Van Wart, Scott A, Ambrose, Paul G, Goodwin, Matthew M, Nagy, Eszter
Published in Open forum infectious diseases (26.11.2018)
Published in Open forum infectious diseases (26.11.2018)
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Monoclonal antibodies targeting different cell wall antigens of group B streptococcus mediate protection in both Fc-dependent and independent manner
Senn, Beatrice M, Visram, Zehra, Meinke, Andreas L, Neubauer, Christina, Gelbmann, Dieter, Sinzinger, Jan, Hanner, Markus, Lundberg, Urban, Boisvert, Heike, Reinscheid, Dieter, von Gabain, Alexander, Nagy, Eszter
Published in Vaccine (31.05.2011)
Published in Vaccine (31.05.2011)
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Immunological fingerprinting of group B streptococci: From circulating human antibodies to protective antigens
Meinke, Andreas L, Senn, Beatrice M, Visram, Zehra, Henics, Tamás Z, Minh, Duc Bui, Schüler, Wolfgang, Neubauer, Christina, Gelbmann, Dieter, Noiges, Birgit, Sinzinger, Jan, Hanner, Markus, Dewasthaly, Shailesh, Lundberg, Urban, Hordnes, Knut, Masoud, Helga, Sevelda, Paul, von Gabain, Alexander, Nagy, Eszter
Published in Vaccine (08.10.2010)
Published in Vaccine (08.10.2010)
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Rna encoding peptidoglycan hydrolase and use thereof for treating bacterial infection
ERBAR Stephanie, VISRAM Zehra, CORSINI Lorenzo, HENNING Andreas, SPIER Anna, SAHIN Ugur, SCHILLE Stefan Albrecht
Year of Publication 01.07.2024
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Year of Publication 01.07.2024
Patent
ANTIBODIES TARGETING A GALACTAN-BASED O-ANTIGEN OF K. PNEUMONIAE
NAGY, Gábor, NAGY, Eszter, VISRAM, Zehra, LUKASIEWICZ, Jolanta Katarzyna, SZIJARTO, Valeria, GUACHALLA, Luis
Year of Publication 13.07.2023
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Year of Publication 13.07.2023
Patent