The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating
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C2C12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment
Zebedin, Eva, Mille, Markus, Speiser, Maria, Zarrabi, Touran, Sandtner, Walter, Latzenhofer, Birgit, Todt, Hannes, Hilber, Karlheinz
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
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Lidocaine: A Foot in the Door of the Inner Vestibule Prevents Ultra-Slow Inactivation of a Voltage-Gated Sodium Channel
Sandtner, Walter, Szendroedi, Julia, Zarrabi, Touran, Zebedin, Eva, Hilber, Karlheinz, Glaaser, Ian, Fozzard, Harry A, Dudley, Samuel C, Todt, Hannes
Published in Molecular pharmacology (01.09.2004)
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Published in Molecular pharmacology (01.09.2004)
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Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures
Cervenka, Rene, Lukacs, Peter, Gawali, Vaibhavkumar S., Ke, Song, Koenig, Xaver, Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Sandtner, Walter, Stary-Weinzinger, Anna, Todt, Hannes
Published in Scientific reports (12.01.2018)
Published in Scientific reports (12.01.2018)
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Exploring the Structure of the Voltage-gated Na+ Channel by an Engineered Drug Access Pathway to the Receptor Site for Local Anesthetics
Lukacs, Peter, Gawali, Vaibhavkumar S., Cervenka, Rene, Ke, Song, Koenig, Xaver, Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Stary-Weinzinger, Anna, Todt, Hannes
Published in The Journal of biological chemistry (01.08.2014)
Published in The Journal of biological chemistry (01.08.2014)
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A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na+ Channel
Zarrabi, Touran, Cervenka, Rene, Sandtner, Walter, Lukacs, Peter, Koenig, Xaver, Hilber, Karlheinz, Mille, Markus, Lipkind, Gregory M., Fozzard, Harry A., Todt, Hannes
Published in The Journal of biological chemistry (10.12.2010)
Published in The Journal of biological chemistry (10.12.2010)
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The First Crystal Structure of a Voltage-Gated Na+ Channel Predicts a New Determinant of External Access for Hydrophilic Local Anaesthetics
Lukács, Péter, Cervenka, René, Gawali, Vaibhavkumar, Koenig, Xaver, Mike, Ágnes K., Rubi, Lena, Zarrabi, Touran, Hilber, Karlheinz, Fozzard, Harry A., Todt, Hannes
Published in Biophysical journal (29.01.2013)
Published in Biophysical journal (29.01.2013)
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Double Mutant Perturbation Analysis Reveals High Conformational Stability Of The Domain IV S6 Segment Of The Voltage-gated Na Channel
Cervenka, Rene, Zarrabi, Touran, Koenig, Xaver, Fozzard, Harry A., Hilber, Karlheinz, Todt, Hannes
Published in Biophysical journal (01.02.2009)
Published in Biophysical journal (01.02.2009)
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Speeding the Recovery from Ultraslow Inactivation of Voltage-Gated Na + Channels by Metal Ion Binding to the Selectivity Filter: A Foot- on-the-Door?
Szendroedi, Julia, Sandtner, Walter, Zarrabi, Touran, Zebedin, Eva, Hilber, Karlheinz, Dudley, Samuel C., Fozzard, Harry A., Todt, Hannes
Published in Biophysical journal (15.12.2007)
Published in Biophysical journal (15.12.2007)
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C2C12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment
ZEBEDIN, Eva, MILLE, Markus, SPEISER, Maria, ZARRABI, Touran, SANDTNER, Walter, LATZENHOFER, Birgit, TODT, Hannes, HILBER, Karlheinz
Published in American journal of physiology. Heart and circulatory physiology (2007)
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Published in American journal of physiology. Heart and circulatory physiology (2007)
Journal Article
C 2 C 12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment
Zebedin, Eva, Mille, Markus, Speiser, Maria, Zarrabi, Touran, Sandtner, Walter, Latzenhofer, Birgit, Todt, Hannes, Hilber, Karlheinz
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
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Journal Article
A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel
Cervenka, René, Lukács, Péter, Zarrabi, Touran, Koenig, Xaver, Mike, Agnés, Hilber, Karlheinz, Todt, Hannes
Published in BMC pharmacology (16.11.2010)
Published in BMC pharmacology (16.11.2010)
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The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant NaV1.4 channel
Lukács, Péter, Cervenka, René, Koenig, Xaver, Mike, Agnés, Zarrabi, Touran, Hilber, Karlheinz, Todt, Hannes
Published in BMC pharmacology (16.11.2010)
Published in BMC pharmacology (16.11.2010)
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Journal Article
The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant NaV 1.4 channel
Lukács, Péter, Cervenka, René, Koenig, Xaver, Mike, Agnés, Zarrabi, Touran, Hilber, Karlheinz, Todt, Hannes
Published in BMC pharmacology (01.01.2010)
Published in BMC pharmacology (01.01.2010)
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From frog oocytes to mammalian cells: substantial differences in modulation of NaV1.4 channel slow kinetic behaviour by the β1 subunit
Lukács, Péter, Cervenka, René, Zarrabi, Touran, König, Xaver, Hilber, Karlheinz, Todt, Hannes
Published in BMC pharmacology (12.11.2009)
Published in BMC pharmacology (12.11.2009)
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Double mutant gating perturbation analysis predicts a high conformational stability of the domain IV S6 segment of the voltage-gated Na+ channel
Cervenka, René, Zarrabi, Touran, Lukács, Péter, König, Xaver, Hilber, Karlheinz, Todt, Hannes
Published in BMC pharmacology (12.11.2009)
Published in BMC pharmacology (12.11.2009)
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