Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study
Lalonde, Emilie, MSc, Ishkanian, Adrian S, MD, Sykes, Jenna, MMath, Fraser, Michael, PhD, Ross-Adams, Helen, PhD, Erho, Nicholas, MSc, Dunning, Mark J, PhD, Halim, Silvia, MSc, Lamb, Alastair D, FRCS, Moon, Nathalie C, MMath, Zafarana, Gaetano, PhD, Warren, Anne Y, FRCPath, Meng, Xianyue, MSc, Thoms, John, MD, Grzadkowski, Michal R, BMath, Berlin, Alejandro, MD, Have, Cherry L, BSc, Ramnarine, Varune R, BCS, Yao, Cindy Q, MSc, Malloff, Chad A, MSc, Lam, Lucia L, BSc, Xie, Honglei, MMath, Harding, Nicholas J, PhD, Mak, Denise Y F, PhD, Chu, Kenneth C, PhD, Chong, Lauren C, BCS, Sendorek, Dorota H, BSc, P'ng, Christine, BSc, Collins, Colin C, Prof, Squire, Jeremy A, Prof, Jurisica, Igor, Prof, Cooper, Colin, PhD, Eeles, Rosalind, Prof, Pintilie, Melania, MSc, Dal Pra, Alan, MD, Davicioni, Elai, PhD, Lam, Wan L, Prof, Milosevic, Michael, MD, Neal, David E, Prof, van der Kwast, Theodorus, Prof, Boutros, Paul C, Prof, Bristow, Robert G, Prof
Published in The lancet oncology (01.12.2014)
Published in The lancet oncology (01.12.2014)
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Copy number alterations of c‐MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy
Zafarana, Gaetano, Ishkanian, Adrian S., Malloff, Chad A., Locke, Jennifer A., Sykes, Jenna, Thoms, John, Lam, Wan L., Squire, Jeremy A., Yoshimoto, Maisa, Ramnarine, Varune Rohan, Meng, Alice, Ahmed, Omar, Jurisca, Igor, Milosevic, Michael, Pintilie, Melania, van der Kwast, Theo, Bristow, Robert G.
Published in Cancer (15.08.2012)
Published in Cancer (15.08.2012)
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Gold nanoparticle mediated combined cancer therapy
Yang, Celina, Bromma, Kyle, Di Ciano-Oliveira, Caterina, Zafarana, Gaetano, van Prooijen, Monique, Chithrani, Devika B.
Published in Cancer nanotechnology (01.12.2018)
Published in Cancer nanotechnology (01.12.2018)
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The Role of SMAD4 in Human Embryonic Stem Cell Self‐Renewal and Stem Cell Fate
Avery, Stuart, Zafarana, Gaetano, Gokhale, Paul J., Andrews, Peter W.
Published in Stem cells (Dayton, Ohio) (01.05.2010)
Published in Stem cells (Dayton, Ohio) (01.05.2010)
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Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma
McKee, Chad M, Xu, Danmei, Cao, Yunhong, Kabraji, Sheheryar, Allen, Danny, Kersemans, Veerle, Beech, John, Smart, Sean, Hamdy, Freddie, Ishkanian, Adrian, Sykes, Jenna, Pintile, Melania, Milosevic, Michael, van der Kwast, Theodorus, Zafarana, Gaetano, Ramnarine, Varune Rohan, Jurisica, Igor, Mallof, Chad, Lam, Wan, Bristow, Robert G, Muschel, Ruth J
Published in The Journal of clinical investigation (01.11.2012)
Published in The Journal of clinical investigation (01.11.2012)
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Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones
MCINTYRE, Alan, SUMMERSGILL, Brenda, CLARK, Jeremy, SHIPLEY, Janet, JAFER, Osman, RODRIGUEZ, Sandrine, ZAFARANA, Gaetano, OOSTERHUIS, J. Wolter, GILLIS, Ad J. M, LOOIJENGA, Leendert, COOPER, Colin, HUDDART, Robert
Published in Oncogene (02.12.2004)
Published in Oncogene (02.12.2004)
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12p-Amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH
ZAFARANA, Gaetano, GRYGALEWICZ, Beata, SCHOENMAKERS, Eric F. P. M, LOOIJENGA, Leendert H. J, VELTMAN, Joris A, GILLIS, Ad J. M, VISSERS, Lisenka E. L. M, VAN DE VLIET, Walter, VAN GURP, Ruud Jhlm, STOOP, Hans, DEBIEC-RYCHTER, Maria, OOSTERHUIS, Jan Wolter, VAN KESSEL, Ad Geurts
Published in Oncogene (23.10.2003)
Published in Oncogene (23.10.2003)
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In vivo studies of the PARP inhibitor, AZD-2281, in combination with fractionated radiotherapy: An exploration of the therapeutic ratio
Gani, Cihan, Coackley, Carla, Kumareswaran, Ramya, Schütze, Christina, Krause, Mechthild, Zafarana, Gaetano, Bristow, Robert G
Published in Radiotherapy and oncology (01.09.2015)
Published in Radiotherapy and oncology (01.09.2015)
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Journal Article
Spatial genomic heterogeneity within localized, multifocal prostate cancer
Boutros, Paul C, Fraser, Michael, Harding, Nicholas J, de Borja, Richard, Trudel, Dominique, Lalonde, Emilie, Meng, Alice, Hennings-Yeomans, Pablo H, McPherson, Andrew, Sabelnykova, Veronica Y, Zia, Amin, Fox, Natalie S, Livingstone, Julie, Shiah, Yu-Jia, Wang, Jianxin, Beck, Timothy A, Have, Cherry L, Chong, Taryne, Sam, Michelle, Johns, Jeremy, Timms, Lee, Buchner, Nicholas, Wong, Ada, Watson, John D, Simmons, Trent T, P'ng, Christine, Zafarana, Gaetano, Nguyen, Francis, Luo, Xuemei, Chu, Kenneth C, Prokopec, Stephenie D, Sykes, Jenna, Dal Pra, Alan, Berlin, Alejandro, Brown, Andrew, Chan-Seng-Yue, Michelle A, Yousif, Fouad, Denroche, Robert E, Chong, Lauren C, Chen, Gregory M, Jung, Esther, Fung, Clement, Starmans, Maud H W, Chen, Hanbo, Govind, Shaylan K, Hawley, James, D'Costa, Alister, Pintilie, Melania, Waggott, Daryl, Hach, Faraz, Lambin, Philippe, Muthuswamy, Lakshmi B, Cooper, Colin, Eeles, Rosalind, Neal, David, Tetu, Bernard, Sahinalp, Cenk, Stein, Lincoln D, Fleshner, Neil, Shah, Sohrab P, Collins, Colin C, Hudson, Thomas J, McPherson, John D, van der Kwast, Theodorus, Bristow, Robert G
Published in Nature genetics (01.07.2015)
Published in Nature genetics (01.07.2015)
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Abstract 2032: Investigating the contribution of mTORC1-dependent signaling in the microenvironment to cancer onset in Li-Fraumeni syndrome
Giovino, Camilla, Patel, Nish, Paramathas, Sangeetha, Zafarana, Gaetano, Kafri, Ran, Malkin, David
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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BRCA Status Does Not Predict Synergism of a Carboplatin and Olaparib Combination in High-Grade Serous Ovarian Cancer Cell Lines
Shen, Yen Ting, Evans, James C, Zafarana, Gaetano, Allen, Christine, Piquette-Miller, Micheline
Published in Molecular pharmaceutics (02.07.2018)
Published in Molecular pharmaceutics (02.07.2018)
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Hypoxia and Cellular Localization Influence the Radiosensitizing Effect of Gold Nanoparticles (AuNPs) in Breast Cancer Cells
Cui, Lei, Tse, Kenneth, Zahedi, Payam, Harding, Shane M., Zafarana, Gaetano, Jaffray, David A., Bristow, Robert G., Allen, Christine
Published in Radiation research (01.11.2014)
Published in Radiation research (01.11.2014)
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Abstract 2214: Dynamic transcriptome analysis of DNA damage pathways under hypoxia
Lo, Winnie W., Zafarana, Gaetano, Bristow, Robert G.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Correction: Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model
Borst, Gerben R, Kumareswaran, Ramya, Yücel, Hatice, Telli, Seyda, Do, Trevor, McKee, Trevor, Zafarana, Gaetano, Jonkers, Jos, Verheij, Marcel, O'Connor, Mark J, Rottenberg, Sven, Bristow, Robert G
Published in Oncotarget (28.04.2020)
Published in Oncotarget (28.04.2020)
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Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model
Borst, Gerben R, Kumareswaran, Ramya, Yücel, Hatice, Telli, Seyda, Do, Trevor, McKee, Trevor, Zafarana, Gaetano, Jonkers, Jos, Verheij, Marcel, O'Connor, Mark J, Rottenberg, Sven, Bristow, Robert G
Published in Oncotarget (20.10.2017)
Published in Oncotarget (20.10.2017)
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Journal Article
Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer
Ishkanian, Adrian S., Zafarana, Gaetano, Thoms, John, Bristow, Robert G.
Published in Acta oncologica (01.10.2010)
Published in Acta oncologica (01.10.2010)
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NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
LOCKE, Jennifer A, ZAFARANA, Gaetano, SYKES, Jenna, ROHAN RAMNARINE, Varune, MENG, Alice, AHMED, Omer, JURISICA, Igor, DER KWAST, Theo Van, BRISTOW, Robert G, ISHKANIAN, Adrian S, MILOSEVIC, Michael, THOMS, John, HAVE, Cherry L, MALLOFF, Chad A, LAM, Wan L, SQUIRE, Jeremy A, PINTILIE, Melania
Published in Clinical cancer research (2012)
Published in Clinical cancer research (2012)
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