The Leptin Receptor Complex: Heavier Than Expected?
Wauman, Joris, Zabeau, Lennart, Tavernier, Jan
Published in Frontiers in endocrinology (Lausanne) (21.02.2017)
Published in Frontiers in endocrinology (Lausanne) (21.02.2017)
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Journal Article
Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies
Huyghe, Leander, Van Parys, Alexander, Cauwels, Anje, Van Lint, Sandra, De Munter, Stijn, Bultinck, Jennyfer, Zabeau, Lennart, Hostens, Jeroen, Goethals, An, Vanderroost, Nele, Verhee, Annick, Uzé, Gilles, Kley, Niko, Peelman, Frank, Vandekerckhove, Bart, Brouckaert, Peter, Tavernier, Jan
Published in EMBO molecular medicine (07.02.2020)
Published in EMBO molecular medicine (07.02.2020)
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Journal Article
The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma
McMurphy, Travis, Xiao, Run, Magee, Daniel, Slater, Andrew, Zabeau, Lennart, Tavernier, Jan, Cao, Lei
Published in PloS one (28.02.2014)
Published in PloS one (28.02.2014)
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Journal Article
High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma
Daneels, Willem, Van Parys, Alexander, Huyghe, Leander, Rogge, Elke, De Rouck, Steffi, Christiaen, Ruben, Zabeau, Lennart, Taveirne, Sylvie, Van Dorpe, Jo, Kley, Niko, Cauwels, Anje, Depla, Erik, Tavernier, Jan, Offner, Fritz
Published in Experimental hematology & oncology (03.06.2024)
Published in Experimental hematology & oncology (03.06.2024)
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Journal Article
1402 A potent, CD8 T cell targeted IL-2 A-Kine with a broad therapeutic window induces antitumor immunity in syngeneic and humanized mouse tumor models
Zabeau, Lennart, Cauwels, Anje, Parys, Alexander Van, Taveirne, Sylvie, Lopes, Jared E, Depla, Erik, Kley, Niko
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
10th antibody industrial symposium: new developments in antibody and adoptive cell therapies
Antunes, Ana, Alvarez-Vallina, Luis, Bertoglio, Federico, Bouquin, Nicolas, Cornen, Stéphanie, Duffieux, Francis, Ferré, Pierre, Gillet, Raphaëlle, Jorgensen, Christian, Leick, Mark B, Maillère, Bernard, Negre, Hélène, Pelegrin, Mireia, Poirier, Nicolas, Reusch, Dietmar, Robert, Bruno, Serre, Guy, Vicari, Alain, Villalba, Martin, Volpers, Christoph, Vuddamalay, Gavin, Watier, Hervé, Wurch, Thierry, Zabeau, Lennart, Zielonka, Stefan, Zhang, Baolin, Beck, Alain, Martineau, Pierre
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Journal Article
Kinetics of leptin binding to the Q223R leptin receptor
Verkerke, Hans, Naylor, Caitlin, Zabeau, Lennart, Tavernier, Jan, Petri, Jr, William A, Marie, Chelsea
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
The ins and outs of leptin receptor activation
Zabeau, Lennart, Lavens, Delphine, Peelman, Frank, Eyckerman, Sven, Vandekerckhove, Joël, Tavernier, Jan
Published in FEBS Letters (03.07.2003)
Published in FEBS Letters (03.07.2003)
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Book Review
Journal Article
Mapping of the Leptin Binding Sites and Design of a Leptin Antagonist
Peelman, Frank, Van Beneden, Katrien, Zabeau, Lennart, Iserentant, Hannes, Ulrichts, Peter, Defeau, Delphine, Verhee, Annick, Catteeuw, Dominiek, Elewaut, Dirk, Tavernier, Jan
Published in The Journal of biological chemistry (24.09.2004)
Published in The Journal of biological chemistry (24.09.2004)
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Journal Article
Mapping of Binding Site III in the Leptin Receptor and Modeling of a Hexameric Leptin·Leptin Receptor Complex
Peelman, Frank, Iserentant, Hannes, De Smet, Anne-Sophie, Vandekerckhove, Joël, Zabeau, Lennart, Tavernier, Jan
Published in The Journal of biological chemistry (02.06.2006)
Published in The Journal of biological chemistry (02.06.2006)
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Journal Article
Biologically active, magnICON®-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures
Nagels, Bieke, Van Damme, Els J.M., Callewaert, Nico, Zabeau, Lennart, Tavernier, Jan, Delanghe, Joris R., Boets, Annemie, Castilho, Alexandra, Weterings, Koen
Published in Journal of biotechnology (31.08.2012)
Published in Journal of biotechnology (31.08.2012)
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Journal Article
Functional Analysis of Leptin Receptor Activation Using a Janus Kinase/Signal Transducer and Activator of Transcription Complementation Assay
Zabeau, Lennart, Defeau, Delphine, Van der Heyden, José, Iserentant, Hannes, Vandekerckhove, Joël, Tavernier, Jan
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2004)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2004)
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Journal Article
Leptin Receptor Activation Depends on Critical Cysteine Residues in Its Fibronectin Type III Subdomains
Zabeau, Lennart, Defeau, Delphine, Iserentant, Hannes, Vandekerckhove, Joël, Peelman, Frank, Tavernier, Jan
Published in The Journal of biological chemistry (17.06.2005)
Published in The Journal of biological chemistry (17.06.2005)
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Journal Article
Leptin induces inflammation-related genes in RINm5F insulinoma cells
Hekerman, Paul, Zeidler, Julia, Korfmacher, Stefanie, Bamberg-Lemper, Simone, Knobelspies, Holger, Zabeau, Lennart, Tavernier, Jan, Becker, Walter
Published in BMC molecular biology (23.05.2007)
Published in BMC molecular biology (23.05.2007)
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Journal Article
20 YEARS OF LEPTIN: Insights into signaling assemblies of the leptin receptor
Peelman, Frank, Zabeau, Lennart, Moharana, Kedar, Savvides, Savvas N, Tavernier, Jan
Published in Journal of endocrinology (01.10.2014)
Published in Journal of endocrinology (01.10.2014)
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Journal Article
Amyloid Beta Peptide Is an Endogenous Negative Allosteric Modulator of Leptin Receptor
Cecon, Erika, Lhomme, Tori, Maurice, Tangui, Luka, Marine, Chen, Min, Silva, Anisia, Wauman, Joris, Zabeau, Lennart, Tavernier, Jan, Prévot, Vincent, Dam, Julie, Jockers, Ralf
Published in Neuroendocrinology (01.03.2021)
Published in Neuroendocrinology (01.03.2021)
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