Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation
Jirkovský, Eduard, Jirkovská, Anna, Bavlovič-Piskáčková, Hana, Skalická, Veronika, Pokorná, Zuzana, Karabanovich, Galina, Kollárová-Brázdová, Petra, Kubeš, Jan, Lenčová-Popelová, Olga, Mazurová, Yvona, Adamcová, Michaela, Lyon, Alexander R, Roh, Jaroslav, Šimůnek, Tomáš, Štěrbová-Kovaříková, Petra, Štěrba, Martin
Published in Circulation. Heart failure (01.11.2021)
Published in Circulation. Heart failure (01.11.2021)
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Molecular remodeling of left and right ventricular myocardium in chronic anthracycline cardiotoxicity and post-treatment follow up
Lenco, Juraj, Lencová-Popelová, Olga, Å imůnek, Tomás, Gersl, Vladimír, Jirkovský, Eduard, Mazurová, Yvona, Adamcová, Michaela, Å tÄrba, Martin
Published in PloS one (07.05.2014)
Published in PloS one (07.05.2014)
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Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo
Kollárová-Brázdová, Petra, Lenčová-Popelová, Olga, Karabanovich, Galina, Kocúrová-Lengvarská, Júlia, Kubeš, Jan, Váňová, Nela, Mazurová, Yvona, Adamcová, Michaela, Jirkovská, Anna, Holečková, Magdalena, Šimůnek, Tomáš, Štěrbová-Kovaříková, Petra, Roh, Jaroslav, Štěrba, Martin
Published in Clinical science (1979) (13.08.2021)
Published in Clinical science (1979) (13.08.2021)
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Journal Article
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II β Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
Kollárová-Brázdová, Petra, Jirkovská, Anna, Karabanovich, Galina, Pokorná, Zuzana, Bavlovič Piskáčková, Hana, Jirkovský, Eduard, Kubeš, Jan, Lenčová-Popelová, Olga, Mazurová, Yvona, Adamcová, Michaela, Skalická, Veronika, Štěrbová-Kovaříková, Petra, Roh, Jaroslav, Šimůnek, Tomáš, Štěrba, Martin
Published in The Journal of pharmacology and experimental therapeutics (01.06.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2020)
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Primary prevention of chronic anthracycline cardiotoxicity with ACE inhibitor is temporarily effective in rabbits, but benefits wane in post-treatment follow-up
Pokorná, Zuzana, Kollárová-Brázdová, Petra, Lenčová-Popelová, Olga, Jirkovský, Eduard, Kubeš, Jan, Mazurová, Yvona, Adamcová, Michaela, Holečková, Magdalena, Palička, Vladimír, Šimůnek, Tomáš, Štěrba, Martin
Published in Clinical science (1979) (14.01.2022)
Published in Clinical science (1979) (14.01.2022)
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Cardiac miRNA expression during the development of chronic anthracycline-induced cardiomyopathy using an experimental rabbit model
Adamcova, Michaela, Parova, Helena, Lencova-Popelova, Olga, Kollarova-Brazdova, Petra, Baranova, Ivana, Slavickova, Marcela, Stverakova, Tereza, Mikyskova, Petra Sauer, Mazurova, Yvona, Sterba, Martin
Published in Frontiers in pharmacology (03.01.2024)
Published in Frontiers in pharmacology (03.01.2024)
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Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane
Lenčová-Popelová, Olga, Jirkovský, Eduard, Jansová, Hana, Jirkovská-Vávrová, Anna, Vostatková-Tichotová, Lucie, Mazurová, Yvona, Adamcová, Michaela, Chládek, Jaroslav, Hroch, Miloš, Pokorná, Zuzana, Geršl, Vladimír, Šimůnek, Tomáš, Štěrba, Martin
Published in Journal of molecular and cellular cardiology (01.02.2016)
Published in Journal of molecular and cellular cardiology (01.02.2016)
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Proteomic insights into chronic anthracycline cardiotoxicity
Štěrba, Martin, Popelová, Olga, Lenčo, Juraj, Fučíková, Alena, Brčáková, Eva, Mazurová, Yvona, Jirkovský, Eduard, Šimůnek, Tomáš, Adamcová, Michaela, Mičuda, Stanislav, Stulík, Jiří, Geršl, Vladimír
Published in Journal of molecular and cellular cardiology (01.05.2011)
Published in Journal of molecular and cellular cardiology (01.05.2011)
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Journal Article
Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits
Jirkovský, Eduard, Lenčová-Popelová, Olga, Hroch, Miloš, Adamcová, Michaela, Mazurová, Yvona, Vávrová, Jaroslava, Mičuda, Stanislav, Šimůnek, Tomáš, Geršl, Vladimír, Štěrba, Martin
Published in Toxicology (Amsterdam) (15.09.2013)
Published in Toxicology (Amsterdam) (15.09.2013)
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Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value
Adamcova, Michaela, Lencova-Popelova, Olga, Jirkovsky, Eduard, Mazurova, Yvona, Palicka, Vladimir, Simko, Fedor, Gersl, Vladimir, Sterba, Martin
Published in International journal of cardiology (15.12.2015)
Published in International journal of cardiology (15.12.2015)
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Transgenic Rat Model of Huntington’s Disease : A Histopathological Study and Correlations with Neurodegenerative Process in the Brain of HD Patients
Mazurová, Yvona, Anderova, Miroslava, Němečková, Ivana, Bezrouk, Aleš
Published in BioMed research international (01.01.2014)
Published in BioMed research international (01.01.2014)
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Journal Article
Deferiprone Does Not Protect against Chronic Anthracycline Cardiotoxicity in Vivo
Popelová, Olga, Sterba, Martin, Simůnek, Tomás, Mazurová, Yvona, Guncová, Ivana, Hroch, Milos, Adamcová, Michaela, Gersl, Vladimír
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
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Journal Article
Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?
Lenčová-Popelová, Olga, Jansová, Hana, Jirkovský, Eduard, Bureš, Jan, Jirkovská-Vávrová, Anna, Mazurová, Yvona, Reimerová, Petra, Vostatková, Lucie, Adamcová, Michaela, Hroch, Miloš, Pokorná, Zuzana, Kovaříková, Petra, Šimůnek, Tomáš, Štěrba, Martin
Published in Toxicology (Amsterdam) (30.11.2016)
Published in Toxicology (Amsterdam) (30.11.2016)
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Journal Article
Cardioprotective Effects of a Novel Iron Chelator, Pyridoxal 2-Chlorobenzoyl Hydrazone, in the Rabbit Model of Daunorubicin-Induced Cardiotoxicity
Martin Å tÄrba, Olga PopelovÃ, Tomáš Å imůnek, Yvona MazurovÃ, Anna PotáÄovÃ, Michaela AdamcovÃ, Helena KaiserovÃ, PÅemysl PoÅka, VladimÃr GerÅ¡l
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Intervention of Proliferation and Differentiation of Endogenous Neural Stem Cells in the Neurodegenerative Process of Huntington's Disease Phenotype
Mazurová, Yvona, Gunčová, Ivana, Látr, Ivan, Rudolf, Emil
Published in CNS & neurological disorders drug targets (01.06.2011)
Published in CNS & neurological disorders drug targets (01.06.2011)
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The Novel Iron Chelator, 2-Pyridylcarboxaldehyde 2-Thiophenecarboxyl Hydrazone, Reduces Catecholamine-Mediated Myocardial Toxicity
Mladĕnka, Pr̆emysl, Kalinowski, Danuta S, Hašková, Pavlína, Bobrovová, Zuzana, Hrdina, Radomír, Šimůnek, Tomáš, Nachtigal, Petr, Semecký, Vladimír, Vávrová, Jaroslava, Holečková, Magdaléna, Palicka, Vladimir, Mazurová, Yvona, Jansson, Patric J, Richardson, Des R
Published in Chemical research in toxicology (01.01.2009)
Published in Chemical research in toxicology (01.01.2009)
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Cardiac biomarkers in a model of acute catecholamine cardiotoxicity
Mladěnka, Přemysl, Hrdina, Radomír, Bobrovová, Zuzana, Semecký, Vladimír, Vávrová, Jaroslava, Holečková, Magdaléna, Palicka, Vladimir, Mazurová, Yvona, Nachtigal, Petr
Published in Human & experimental toxicology (01.10.2009)
Published in Human & experimental toxicology (01.10.2009)
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Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: A study of salicylaldehyde isonicotinoyl hydrazone (SIH)
STERBA, Martin, POPELOVA, Olga, GERSL, Vladimir, SIMUNEK, Tomas, MAZUROVA, Yvona, POTACOVA, Anna, ADAMCOVA, Michaela, GUNCOVA, Ivana, KAISEROVA, Helena, PALICKA, Vladimir, PONKA, Premysl
Published in Toxicology (Amsterdam) (25.06.2007)
Published in Toxicology (Amsterdam) (25.06.2007)
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