Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase‑2 Inhibitor with a Phenylbenzamide–Pentapeptide Hybrid Scaffold
Takeuchi, Tomoki, Nomura, Yusaku, Tamita, Tomoko, Nishikawa, Rie, Kakinuma, Hiroyuki, Kojima, Naoki, Hitaka, Kosuke, Tamura, Yunoshin, Kamitani, Masafumi, Mima, Masashi, Nozoe, Akiko, Hayashi, Masato
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Journal Article
Discovery of Aryloxyphenyl–Heptapeptide Hybrids as Potent and Selective Matrix Metalloproteinase‑2 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
Takeuchi, Tomoki, Hayashi, Masato, Tamita, Tomoko, Nomura, Yusaku, Kojima, Naoki, Mitani, Akiko, Takeda, Takuya, Hitaka, Kosuke, Kato, Yuki, Kamitani, Masafumi, Mima, Masashi, Toki, Hidetoh, Ohkubo, Masahiko, Nozoe, Akiko, Kakinuma, Hiroyuki
Published in Journal of medicinal chemistry (23.06.2022)
Published in Journal of medicinal chemistry (23.06.2022)
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Journal Article
Discovery of novel indole derivatives as potent and selective inhibitors of proMMP-9 activation
Nishikawa-Shimono, Rie, Kuwabara, Motoi, Fujisaki, Sho, Matsuda, Daisuke, Endo, Mayumi, Kamitani, Masafumi, Futamura, Aya, Nomura, Yusaku, Yamaguchi-Sasaki, Toru, Yabuuchi, Tetsuya, Yamaguchi, Chitose, Tanaka-Yamamoto, Nozomi, Satake, Shunya, Abe-Sato, Kumi, Funayama, Kosuke, Sakata, Mayumi, Takahashi, Shinji, Hirano, Koga, Fukunaga, Takuya, Uozumi, Yoriko, Kato, Sayaka, Tamura, Yunoshin, Nakamori, Tomoaki, Mima, Masashi, Mishima-Tsumagari, Chiemi, Nozawa, Dai, Imai, Yudai, Asami, Taiji
Published in Bioorganic & medicinal chemistry letters (01.01.2024)
Published in Bioorganic & medicinal chemistry letters (01.01.2024)
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Journal Article
Selective Transcription of an Unnatural Naphthyridine:Imidazopyridopyrimidine Base Pair Containing Four Hydrogen Bonds with T7 RNA Polymerase
Nomura, Yusaku, Kashiwagi, Satoshi, Sato, Kousuke, Matsuda, Akira
Published in Angewandte Chemie International Edition (17.11.2014)
Published in Angewandte Chemie International Edition (17.11.2014)
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Journal Article
Synthesis of All Stereoisomers of Monomeric Spectomycin A1/A2 and Evaluation of Their Protein SUMOylation‐Inhibitory Activity
Nomura, Yusaku, Thuaud, Frédéric, Sekine, Daisuke, Ito, Akihiro, Maeda, Satoko, Koshino, Hiroyuki, Hashizume, Daisuke, Muranaka, Atsuya, Cruchter, Thomas, Uchiyama, Masanobu, Ichikawa, Satoshi, Matsuda, Akira, Yoshida, Minoru, Hirai, Go, Sodeoka, Mikiko
Published in Chemistry : a European journal (21.06.2019)
Published in Chemistry : a European journal (21.06.2019)
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Journal Article
Virtual reality and augmented reality applications and simulation in vascular access management with three-dimensional visualization
Yokoyama, Itsuo, Sarai, Tsuyosi, Asai, Toshinori, Kitou, Nobuyuki, Nozaki, Hirotaka, Kondo, Yuki, Nomura, Yusaku, Morizane, Atsushi, Sekikawa, Michi, Liu, Dage
Published in The journal of vascular access (01.05.2019)
Published in The journal of vascular access (01.05.2019)
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Journal Article
POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
TAMITA, Tomoko, SHIMONO, Rie, NOMURA, Yusaku, HAYASHI, Masato, TAKEUCHI, Tomoki
Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
RIE SHIMONO, TOMOKO TAMITA, MASATO HAYASHI, TOMOKI TAKEUCHI, YUSAKU NOMURA
Year of Publication 29.11.2023
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Year of Publication 29.11.2023
Patent
POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
TAMITA, Tomoko, SHIMONO, Rie, NOMURA, Yusaku, HAYASHI, Masato, TAKEUCHI, Tomoki
Year of Publication 29.11.2023
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Year of Publication 29.11.2023
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POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
TAMITA, Tomoko, SHIMONO, Rie, NOMURA, Yusaku, HAYASHI, Masato, TAKEUCHI, Tomoki
Year of Publication 14.09.2022
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Year of Publication 14.09.2022
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Polypeptide having mmp2-inhibitory effect
Masato HAYASHI, Tomoko TAMITA, Tomoki TAKEUCHI, Rie SHIMONO, Yusaku NOMURA
Year of Publication 01.07.2022
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Year of Publication 01.07.2022
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Polypeptide having MMP2-inhibitory effect
TAMITA, Tomoko, SHIMONO, Rie, NOMURA, Yusaku, HAYASHI, Masato, TAKEUCHI, Tomoki
Year of Publication 26.05.2022
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Year of Publication 26.05.2022
Patent
POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
HAYASHI, MASATO, SHIMONO, RIE, TAKEUCHI, TOMOKI, TAMITA, TOMOKO, NOMURA, YUSAKU
Year of Publication 14.05.2021
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Year of Publication 14.05.2021
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POLIPEPTÍDEO TENDO EFEITO MMP2-INIBIDOR
RIE SHIMONO, TOMOKO TAMITA, MASATO HAYASHI, TOMOKI TAKEUCHI, YUSAKU NOMURA
Year of Publication 12.07.2022
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Year of Publication 12.07.2022
Patent
POLYPEPTIDE HAVING MMP2-INHIBITORY EFFECT
TAKEUCHI Tomoki, TAMITA Tomoko, SHIMONO Rie, HAYASHI Masato, NOMURA Yusaku
Year of Publication 30.05.2022
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Year of Publication 30.05.2022
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Polypeptide with MMP2 inhibiting effect
HAYASHI MASATOMO, SHIMONO RIE, NOMURA YUSAKU, TAMITA, TOMOKO, TAKEUCHI TOMOKI
Year of Publication 06.05.2022
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Year of Publication 06.05.2022
Patent
Polypeptide having mmp2-inhibitory effect
HAYASHI, MASATO, SHIMONO, RIE, TAKEUCHI, TOMOKI, TAMITA, TOMOKO, NOMURA, YUSAKU
Year of Publication 01.09.2021
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Year of Publication 01.09.2021
Patent