Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
Castillo, Erika, Leon, Julio, Mazzei, Guianfranco, Abolhassani, Nona, Haruyama, Naoki, Saito, Takashi, Saido, Takaomi, Hokama, Masaaki, Iwaki, Toru, Ohara, Tomoyuki, Ninomiya, Toshiharu, Kiyohara, Yutaka, Sakumi, Kunihiko, LaFerla, Frank M., Nakabeppu, Yusaku
Published in Scientific reports (19.12.2017)
Published in Scientific reports (19.12.2017)
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Journal Article
Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain
Abolhassani, Nona, Leon, Julio, Sheng, Zijing, Oka, Sugako, Hamasaki, Hideomi, Iwaki, Toru, Nakabeppu, Yusaku
Published in Mechanisms of ageing and development (01.01.2017)
Published in Mechanisms of ageing and development (01.01.2017)
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Journal Article
Oxidative Stress and Microglial Response in Retinitis Pigmentosa
Murakami, Yusuke, Nakabeppu, Yusaku, Sonoda, Koh-Hei
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Journal Article
PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions
Ishii, Takashi, Igawa, Tatsuhiro, Hayakawa, Hiroshi, Fujita, Tsugumi, Sekiguchi, Mutsuo, Nakabeppu, Yusaku
Published in The Journal of biological chemistry (21.08.2020)
Published in The Journal of biological chemistry (21.08.2020)
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Journal Article
Oxidative damage in nucleic acids and Parkinson's disease
Nakabeppu, Yusaku, Tsuchimoto, Daisuke, Yamaguchi, Hiroo, Sakumi, Kunihiko
Published in Journal of neuroscience research (01.04.2007)
Published in Journal of neuroscience research (01.04.2007)
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Journal Article
MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis
Oka, Sugako, Leon, Julio, Sakumi, Kunihiko, Abolhassani, Nona, Sheng, Zijing, Tsuchimoto, Daisuke, LaFerla, Frank M., Nakabeppu, Yusaku
Published in Scientific reports (23.03.2021)
Published in Scientific reports (23.03.2021)
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8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions
Leon, Julio, Sakumi, Kunihiko, Castillo, Erika, Sheng, Zijing, Oka, Sugako, Nakabeppu, Yusaku
Published in Scientific reports (25.02.2016)
Published in Scientific reports (25.02.2016)
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Journal Article
Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition
Nakamura, Teruya, Koga‐Ogawa, Yukari, Fujimiya, Kana, Chirifu, Mami, Goto, Masataka, Ikemizu, Shinji, Nakabeppu, Yusaku, Yamagata, Yuriko
Published in FEBS letters (01.07.2023)
Published in FEBS letters (01.07.2023)
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Journal Article
MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model
Sakamoto, Hiroki, Miyanishi, Koji, Tanaka, Shingo, Ito, Ryo, Hamaguchi, Kota, Sakurada, Akira, Sato, Masanori, Kubo, Tomohiro, Osuga, Takahiro, Murase, Kazuyuki, Takada, Kohichi, Nakabeppu, Yusaku, Kobune, Masayoshi, Kato, Junji
Published in Scientific reports (11.02.2021)
Published in Scientific reports (11.02.2021)
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Journal Article
8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle
Vartanian, Vladimir, Tumova, Jana, Dobrzyn, Pawel, Dobrzyn, Agnieszka, Nakabeppu, Yusaku, Lloyd, R Stephen, Sampath, Harini
Published in PloS one (20.07.2017)
Published in PloS one (20.07.2017)
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Journal Article
Celecoxib and 2,5‐dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β‐catenin signaling pathway
Egashira, Issei, Takahashi‐Yanaga, Fumi, Nishida, Risa, Arioka, Masaki, Igawa, Kazunobu, Tomooka, Katsuhiko, Nakatsu, Yoshimichi, Tsuzuki, Teruhisa, Nakabeppu, Yusaku, Kitazono, Takanari, Sasaguri, Toshiyuki
Published in Cancer science (01.01.2017)
Published in Cancer science (01.01.2017)
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Journal Article
8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes
Haruyama, Naoki, Sakumi, Kunihiko, Katogi, Atsuhisa, Tsuchimoto, Daisuke, De Luca, Gabriele, Bignami, Margherita, Nakabeppu, Yusaku
Published in Progress in neurobiology (01.09.2019)
Published in Progress in neurobiology (01.09.2019)
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Journal Article
Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis
Yogianti, Flandiana, Kunisada, Makoto, Nakano, Eiji, Ono, Ryusuke, Sakumi, Kunihiko, Oka, Sugako, Nakabeppu, Yusaku, Nishigori, Chikako
Published in Journal of investigative dermatology (01.10.2014)
Published in Journal of investigative dermatology (01.10.2014)
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