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Wang, Chao, Fan, Li, Khawaja, Rabia R., Liu, Bangyan, Zhan, Lihong, Kodama, Lay, Chin, Marcus, Li, Yaqiao, Le, David, Zhou, Yungui, Condello, Carlo, Grinberg, Lea T., Seeley, William W., Miller, Bruce L., Mok, Sue-Ann, Gestwicki, Jason E., Cuervo, Ana Maria, Luo, Wenjie, Gan, Li
Published in Nature communications (12.04.2022)
Published in Nature communications (12.04.2022)
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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
Min, Sang-Won, Chen, Xu, Tracy, Tara E, Li, Yaqiao, Zhou, Yungui, Wang, Chao, Shirakawa, Kotaro, Minami, S Sakura, Defensor, Erwin, Mok, Sue Ann, Sohn, Peter Dongmin, Schilling, Birgit, Cong, Xin, Ellerby, Lisa, Gibson, Bradford W, Johnson, Jeffrey, Krogan, Nevan, Shamloo, Mehrdad, Gestwicki, Jason, Masliah, Eliezer, Verdin, Eric, Gan, Li
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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Microglial microRNAs mediate sex-specific responses to tau pathology
Kodama, Lay, Guzman, Elmer, Etchegaray, Jon I., Li, Yaqiao, Sayed, Faten A., Zhou, Lu, Zhou, Yungui, Zhan, Lihong, Le, David, Udeochu, Joe C., Clelland, Claire D., Cheng, Zuolin, Yu, Guoqiang, Li, Qingyun, Kosik, Kenneth S., Gan, Li
Published in Nature neuroscience (01.02.2020)
Published in Nature neuroscience (01.02.2020)
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Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy
Sayed, Faten A., Telpoukhovskaia, Maria, Kodama, Lay, Li, Yaqiao, Zhou, Yungui, Le, David, Hauduc, Axel, Ludwig, Connor, Gao, Fuying, Clelland, Claire, Zhan, Lihong, Cooper, Yonatan A., Davalos, Dimitrios, Akassoglou, Katerina, Coppola, Giovanni, Gan, Li
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2018)
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Journal Article
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Min, Sang-Won, Cho, Seo-Hyun, Zhou, Yungui, Schroeder, Sebastian, Haroutunian, Vahram, Seeley, William W., Huang, Eric J., Shen, Yong, Masliah, Eliezer, Mukherjee, Chandrani, Meyers, David, Cole, Philip A., Ott, Melanie, Gan, Li
Published in Neuron (Cambridge, Mass.) (23.09.2010)
Published in Neuron (Cambridge, Mass.) (23.09.2010)
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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
Zhan, Lihong, Krabbe, Grietje, Du, Fei, Jones, Ian, Reichert, Meredith C, Telpoukhovskaia, Maria, Kodama, Lay, Wang, Chao, Cho, Seo-Hyun, Sayed, Faten, Li, Yaqiao, Le, David, Zhou, Yungui, Shen, Yin, West, Brian, Gan, Li
Published in PLoS biology (08.02.2019)
Published in PLoS biology (08.02.2019)
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Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
Tracy, Tara E., Sohn, Peter Dongmin, Minami, S. Sakura, Wang, Chao, Min, Sang-Won, Li, Yaqiao, Zhou, Yungui, Le, David, Lo, Iris, Ponnusamy, Ravikumar, Cong, Xin, Schilling, Birgit, Ellerby, Lisa M., Huganir, Richard L., Gan, Li
Published in Neuron (Cambridge, Mass.) (20.04.2016)
Published in Neuron (Cambridge, Mass.) (20.04.2016)
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CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease
Cho, Seo-Hyun, Sun, Binggui, Zhou, Yungui, Kauppinen, Tiina M., Halabisky, Brian, Wes, Paul, Ransohoff, Richard M., Gan, Li
Published in The Journal of biological chemistry (16.09.2011)
Published in The Journal of biological chemistry (16.09.2011)
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A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
Zhan, Lihong, Fan, Li, Kodama, Lay, Sohn, Peter Dongmin, Wong, Man Ying, Mousa, Gergey Alzaem, Zhou, Yungui, Li, Yaqiao, Gan, Li
Published in eLife (15.10.2020)
Published in eLife (15.10.2020)
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Antiamyloidogenic and Neuroprotective Functions of Cathepsin B: Implications for Alzheimer's Disease
Mueller-Steiner, Sarah, Zhou, Yungui, Arai, Hideaki, Roberson, Erik D., Sun, Binggui, Chen, Jennifer, Wang, Xin, Yu, Guiqiu, Esposito, Luke, Mucke, Lennart, Gan, Li
Published in Neuron (Cambridge, Mass.) (21.09.2006)
Published in Neuron (Cambridge, Mass.) (21.09.2006)
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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
Sanchez-Mejia, Rene O, Newman, John W, Toh, Sandy, Yu, Gui-Qiu, Zhou, Yungui, Halabisky, Brian, Cissé, Moustapha, Scearce-Levie, Kimberly, Cheng, Irene H, Gan, Li, Palop, Jorge J, Bonventre, Joseph V, Mucke, Lennart
Published in Nature neuroscience (01.11.2008)
Published in Nature neuroscience (01.11.2008)
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Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia
Telpoukhovskaia, Maria A., Liu, Kai, Sayed, Faten A., Etchegaray, Jon Iker, Xie, Min, Zhan, Lihong, Li, Yaqiao, Zhou, Yungui, Le, David, Bahr, Ben A., Bogyo, Matthew, Ding, Sheng, Gan, Li
Published in Scientific reports (13.08.2020)
Published in Scientific reports (13.08.2020)
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Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease
Sun, Binggui, Zhou, Yungui, Halabisky, Brian, Lo, Iris, Cho, Seo-Hyun, Mueller-Steiner, Sarah, Devidze, Nino, Wang, Xin, Grubb, Anders, Gan, Li
Published in Neuron (Cambridge, Mass.) (23.10.2008)
Published in Neuron (Cambridge, Mass.) (23.10.2008)
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Selective targeting of microglia by quantum dots
Minami, S Sakura, Sun, Binggui, Popat, Ketul, Kauppinen, Tiina, Pleiss, Mike, Zhou, Yungui, Ward, Michael E, Floreancig, Paul, Mucke, Lennart, Desai, Tejal, Gan, Li
Published in Journal of neuroinflammation (24.01.2012)
Published in Journal of neuroinflammation (24.01.2012)
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Turbine Cavitation State Recognition Based on BP Neural Network
Zhou, Yungui, Liu, Zhong, Zou, Shuyun, Zhang, Xuyang
Published in 2019 International Conference on Robots & Intelligent System (ICRIS) (01.06.2019)
Published in 2019 International Conference on Robots & Intelligent System (ICRIS) (01.06.2019)
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Conference Proceeding
A Founder Mutation in Artemis, an SNM1-Like Protein, Causes SCID in Athabascan-Speaking Native Americans
Li, Lanying, Moshous, Despina, Zhou, Yungui, Wang, Junhua, Xie, Gang, Salido, Eduardo, Hu, Diana, de Villartay, Jean-Pierre, Cowan, Morton J
Published in The Journal of immunology (1950) (15.06.2002)
Published in The Journal of immunology (1950) (15.06.2002)
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Cathepsin B Degrades Amyloid-β in Mice Expressing Wild-type Human Amyloid Precursor Protein
Wang, Chao, Sun, Binggui, Zhou, Yungui, Grubb, Anders, Gan, Li
Published in The Journal of biological chemistry (16.11.2012)
Published in The Journal of biological chemistry (16.11.2012)
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Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tracy, Tara E., Madero-Pérez, Jesus, Swaney, Danielle L., Chang, Timothy S., Moritz, Michelle, Konrad, Csaba, Ward, Michael E., Stevenson, Erica, Hüttenhain, Ruth, Kauwe, Grant, Mercedes, Maria, Sweetland-Martin, Lauren, Chen, Xu, Mok, Sue-Ann, Wong, Man Ying, Telpoukhovskaia, Maria, Min, Sang-Won, Wang, Chao, Sohn, Peter Dongmin, Martin, Jordie, Zhou, Yungui, Luo, Wenjie, Trojanowski, John Q., Lee, Virginia M.Y., Gong, Shiaoching, Manfredi, Giovanni, Coppola, Giovanni, Krogan, Nevan J., Geschwind, Daniel H., Gan, Li
Published in Cell (17.02.2022)
Published in Cell (17.02.2022)
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Journal Article
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β
Cho, Seo-Hyun, Chen, Jason A, Sayed, Faten, Ward, Michael E, Gao, Fuying, Nguyen, Thi A, Krabbe, Grietje, Sohn, Peter Dongmin, Lo, Iris, Minami, Sakura, Devidze, Nino, Zhou, Yungui, Coppola, Giovanni, Gan, Li
Published in The Journal of neuroscience (14.01.2015)
Published in The Journal of neuroscience (14.01.2015)
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