Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia
Almeida, Afonso, Aguiar Martins Neto, João Luís, Cebola Cachucho, Ana Patrícia, Euzébio, Mayara, Meng, Xiangyu, Kim, Rathana, Fernandes, Marta, Raposo, Beatriz, Oliveira, Mariana L., Silva Ribeiro, Daniel Filipe, Fragoso, Rita, Zenatti, Priscila P., Soares, Tiago, Ramos de Matos, Mafalda, Corrêa, Juliana Ronchi, dos Santos Dias Duque, Mafalda, Roberts, Kathryn G., Gu, Zhaohui, Qu, Chunxu, Pereira, Clara, Pyne, Susan, Pyne, Nigel J., Barreto, Vasco M., Bernard-Pierrot, Isabelle, Clappier, Emannuelle, Mullighan, Charles G., Grosso, Ana R., Yunes, J. Andrés, Barata, João
Published in Nature communications (14.12.2021)
Published in Nature communications (14.12.2021)
Get full text
Journal Article
IL-7 Contributes to the Progression of Human T-cell Acute Lymphoblastic Leukemias
SILVA, Ana, LARANJEIRA, Angelo B. A, MARTINS, Leila R, CARDOSO, Bruno A, DEMENGEOT, Jocelyne, ANDRES YUNES, J, SEDDON, Benedict, BARATA, Joao T
Published in Cancer research (Chicago, Ill.) (15.07.2011)
Published in Cancer research (Chicago, Ill.) (15.07.2011)
Get full text
Journal Article
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
Barata, João T, Zenatti, Priscila P, Ribeiro, Daniel, Li, Wenqing, Zuurbier, Linda, Silva, Milene C, Paganin, Maddalena, Tritapoe, Julia, Hixon, Julie A, Silveira, André B, Cardoso, Bruno A, Sarmento, Leonor M, Correia, Nádia, Toribio, Maria L, Kobarg, Jörg, Horstmann, Martin, Pieters, Rob, Brandalise, Silvia R, Ferrando, Adolfo A, Meijerink, Jules P, Durum, Scott K, Yunes, J Andrés
Published in Nature genetics (01.10.2011)
Published in Nature genetics (01.10.2011)
Get full text
Journal Article
NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling
Pinto, Inês, Duque, Mafalda, Gonçalves, Joana, Akkapeddi, Padma, Oliveira, Mariana L., Cabrita, Rita, Yunes, J. Andrés, Durum, Scott K., Barata, João T., Fragoso, Rita
Published in Oncogene (30.01.2020)
Published in Oncogene (30.01.2020)
Get full text
Journal Article
PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability
Silva, Ana, Yunes, J Andrés, Cardoso, Bruno A, Martins, Leila R, Jotta, Patrícia Y, Abecasis, Miguel, Nowill, Alexandre E, Leslie, Nick R, Cardoso, Angelo A, Barata, Joao T
Published in The Journal of clinical investigation (01.11.2008)
Published in The Journal of clinical investigation (01.11.2008)
Get full text
Journal Article
How to recognize and workaround pitfalls in QSAR studies: a critical review
Scior, T, Medina-Franco, J L, Do, Q-T, Martínez-Mayorga, K, Yunes Rojas, J A, Bernard, P
Published in Current medicinal chemistry (01.11.2009)
Published in Current medicinal chemistry (01.11.2009)
Get more information
Journal Article
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia
Cardoso, Bruno A, Duque, Mafalda, Gírio, Ana, Fragoso, Rita, Oliveira, Mariana L, Allen, James R, Martins, Leila R, Correia, Nádia C, Silveira, André Bortolini, Veloso, Alexandra, Kimura, Shunsuke, Demoen, Lisa, Matthijssens, Filip, Jeha, Sima, Cheng, Cheng, Pui, Ching-Hon, Grosso, Ana R, Neto, João L, De Almeida, Sérgio F, Van Vlieberghe, Pieter, Mullighan, Charles G, Yunes, J Andres, Langenau, David M, Pflumio, Françoise, Barata, João T
Published in Haematologica (Roma) (01.06.2024)
Published in Haematologica (Roma) (01.06.2024)
Get full text
Journal Article
Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and γ-secretase inhibitors
SILVA, Ana, JOTTA, Patricia Y, SILVEIRA, André B, RIBEIRO, Daniel, BRANDALISE, Silvia R, YUNES, J. Andrés, BARATA, João T
Published in Haematologica (Roma) (01.04.2010)
Published in Haematologica (Roma) (01.04.2010)
Get full text
Journal Article
PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events
Mendes, Rui D., Sarmento, Leonor M., Canté-Barrett, Kirsten, Zuurbier, Linda, Buijs-Gladdines, JessicaG.C.A.M., Póvoa, Vanda, Smits, Willem K., Abecasis, Miguel, Yunes, J. Andres, Sonneveld, Edwin, Horstmann, Martin A., Pieters, Rob, Barata, João T., Meijerink, JulesP.P.
Published in Blood (24.07.2014)
Published in Blood (24.07.2014)
Get full text
Journal Article
Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia
Jotta, P Y, Ganazza, M A, Silva, A, Viana, M B, da Silva, M J, Zambaldi, L J G, Barata, J T, Brandalise, S R, Yunes, J A
Published in Leukemia (01.01.2010)
Published in Leukemia (01.01.2010)
Get full text
Journal Article
IGFBP7 participates in the reciprocal interaction between acute lymphoblastic leukemia and BM stromal cells and in leukemia resistance to asparaginase
Laranjeira, A B A, de Vasconcellos, J F, Sodek, L, Spago, M C, Fornazim, M C, Tone, L G, Brandalise, S R, Nowill, A E, Yunes, J A
Published in Leukemia (01.05.2012)
Published in Leukemia (01.05.2012)
Get full text
Journal Article
Antioxidant responses and oxidative stress after microcystin exposure in the hepatopancreas of an estuarine crab species
Pinho, G.L.L., Moura da Rosa, C., Maciel, F.E., Bianchini, A., Yunes, J.S., Proença, L.A.O., Monserrat, J.M.
Published in Ecotoxicology and environmental safety (01.07.2005)
Published in Ecotoxicology and environmental safety (01.07.2005)
Get full text
Journal Article
TAL1 SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells
Cardoso, B A, de Almeida, S F, Laranjeira, A B A, Carmo-Fonseca, M, Yunes, J A, Coffer, P J, Barata, J T
Published in Leukemia (01.10.2011)
Published in Leukemia (01.10.2011)
Get full text
Journal Article
Chimerism interpretation with a highly sensitive quantitative PCR method: 6 months median latency before chimerism drop below 0.1
Vicente, D C, Laranjeira, A B A, Miranda, E C M, Yunes, J A, de Souza, C A
Published in Bone marrow transplantation (Basingstoke) (01.06.2016)
Published in Bone marrow transplantation (Basingstoke) (01.06.2016)
Get full text
Journal Article
Effects of microcystins over short- and long-term memory and oxidative stress generation in hippocampus of rats
Maidana, M., Carlis, V., Galhardi, F.G., Yunes, J.S., Geracitano, L.A., Monserrat, J.M., Barros, D.M.
Published in Chemico-biological interactions (25.02.2006)
Published in Chemico-biological interactions (25.02.2006)
Get full text
Journal Article
Toxic effects of microcystins in the hepatopancreas of the estuarine crab Chasmagnathus granulatus (Decapoda, Grapsidae)
Pinho, G.L.L., Moura da Rosa, C., Yunes, J.S., Luquet, C.M., Bianchini, A., Monserrat, J.M.
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.08.2003)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.08.2003)
Get full text
Journal Article
Acute effects of Microcystis aeruginosa from the Patos Lagoon estuary, southern Brazil, on the Microcrustacean kalliapseudes schubartii (Crustacea: Tanaidacea)
MONTAGNOLLI, W, ZAMBONI, A, LUVIZOTTO-SANTOS, R, YUNES, J. S
Published in Archives of environmental contamination and toxicology (01.05.2004)
Published in Archives of environmental contamination and toxicology (01.05.2004)
Get full text
Journal Article