Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats
Zhou, Xin, Rougée, Luc R A, Bedwell, David W, Cramer, Jeff W, Mohutsky, Michael A, Calvert, Nathan A, Moulton, Richard D, Cassidy, Kenneth C, Yumibe, Nathan P, Adams, Lisa A, Ruterbories, Kenneth J
Published in Drug metabolism and disposition (01.08.2016)
Published in Drug metabolism and disposition (01.08.2016)
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In Vivo Metabolism-Based Discovery of a Potent Cholesterol Absorption Inhibitor, SCH58235, in the Rat and Rhesus Monkey through the Identification of the Active Metabolites of SCH48461
Van Heek, M, France, C F, Compton, D S, McLeod, R L, Yumibe, N P, Alton, K B, Sybertz, E J, Davis, Jr, H R
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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The use of in vitro metabolic stability for rapid selection of compounds in early discovery based on their expected hepatic extraction ratios
YAU YI LAU, KRISHNA, Gopal, YUMIBE, Nathan P, GROTZ, Diane E, SAPIDOU, Elpida, NORTON, Laura, INHOU CHU, CHEN, Cliff, SOARES, A. D, LIN, Chin-Chung
Published in Pharmaceutical research (01.11.2002)
Published in Pharmaceutical research (01.11.2002)
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Syn and anti bent hydrazine radical cations. Effect of .sigma.,.pi. mixing on spectral properties
Nelsen, Stephen F, Blackstock, Silas C, Yumibe, Nathan P, Frigo, Timothy B, Carpenter, John E, Weinhold, Frank
Published in Journal of the American Chemical Society (01.01.1985)
Published in Journal of the American Chemical Society (01.01.1985)
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Design and Synthesis of a Potent and Selective Triazolone-Based Peroxisome Proliferator-Activated Receptor α Agonist
Xu, Yanping, Mayhugh, Daniel, Saeed, Ashraf, Wang, Xiaodong, Thompson, Richard C, Dominianni, Samuel J, Kauffman, Raymond F, Singh, Jaipal, Bean, James S, Bensch, William R, Barr, Robert J, Osborne, John, Montrose-Rafizadeh, Chahrzad, Zink, Richard W, Yumibe, Nathan P, Huang, Naijia, Luffer-Atlas, Debra, Rungta, Deepa, Maise, Dale E, Mantlo, Nathan B
Published in Journal of medicinal chemistry (20.11.2003)
Published in Journal of medicinal chemistry (20.11.2003)
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