Clinical Relevance of Liquid Chromatography Tandem Mass Spectrometry as an Analytical Method in Microdose Clinical Studies
Yamane, Naoe, Tozuka, Zenzaburo, Kusama, Makiko, Maeda, Kazuya, Ikeda, Toshihiko, Sugiyama, Yuichi
Published in Pharmaceutical research (01.08.2011)
Published in Pharmaceutical research (01.08.2011)
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P-GLYCOPROTEIN PLAYS A MAJOR ROLE IN THE EFFLUX OF FEXOFENADINE IN THE SMALL INTESTINE AND BLOOD-BRAIN BARRIER, BUT ONLY A LIMITED ROLE IN ITS BILIARY EXCRETION
TAHARA, Harunobu, KUSUHARA, Hiroyuki, FUSE, Eiichi, SUGIYAMA, Yuichi
Published in Drug metabolism and disposition (01.07.2005)
Published in Drug metabolism and disposition (01.07.2005)
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Vectorial Transport of Enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in Rat and Human Livers
Liu, Lichuan, Cui, Yunhai, Chung, Alfred Y, Shitara, Yoshihisa, Sugiyama, Yuichi, Keppler, Dietrich, Pang, K Sandy
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Positron emission tomography studies using (15R)-16-m-[11C]tolyl-17,18,19,20-tetranorisocarbacyclin methyl ester for the evaluation of hepatobiliary transport
Takashima, Tadayuki, Nagata, Hiroko, Nakae, Takahiro, Cui, Yilong, Wada, Yasuhiro, Kitamura, Satoshi, Doi, Hisashi, Suzuki, Masaaki, Maeda, Kazuya, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Watanabe, Yasuyoshi
Published in The Journal of pharmacology and experimental therapeutics (01.11.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2010)
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Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain
Kusuhara, Hiroyuki, Sekine, Takashi, Utsunomiya-Tate, Naoko, Tsuda, Minoru, Kojima, Ryoji, Cha, Seok Ho, Sugiyama, Yuichi, Kanai, Yoshikatsu, Endou, Hitoshi
Published in The Journal of biological chemistry (07.05.1999)
Published in The Journal of biological chemistry (07.05.1999)
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Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [ 11C]celecoxib and its major metabolite [ 11C]SC-62807 and in vivo PET evaluation
Takashima-Hirano, Misato, Takashima, Tadayuki, Katayama, Yumiko, Wada, Yasuhiro, Sugiyama, Yuichi, Watanabe, Yasuyoshi, Doi, Hisashi, Suzuki, Masaaki
Published in Bioorganic & medicinal chemistry (01.05.2011)
Published in Bioorganic & medicinal chemistry (01.05.2011)
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Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine
Rost, Daniel, Mahner, Sven, Sugiyama, Yuichi, Stremmel, Wolfgang
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2002)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.04.2002)
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Involvement of Breast Cancer Resistance Protein (BCRP/ABCG2) in the Biliary Excretion and Intestinal Efflux of Troglitazone Sulfate, the Major Metabolite of Troglitazone with a Cholestatic Effect
ENOKIZONO, Junichi, KUSUHARA, Hiroyuki, SUGIYAMA, Yuichi
Published in Drug metabolism and disposition (01.02.2007)
Published in Drug metabolism and disposition (01.02.2007)
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Effect of Genetic Polymorphism of OATP-C (SLCO1B1) on Lipid-Lowering Response to HMG-CoA Reductase Inhibitors
Tachibana-Iimori, Rieko, Tabara, Yasuharu, Kusuhara, Hiroyuki, Kohara, Katsuhiko, Kawamoto, Ryuichi, Nakura, Jun, Tokunaga, Katsushi, Kondo, Ikuko, Sugiyama, Yuichi, Miki, Tetsuro
Published in DRUG METABOLISM AND PHARMACOKINETICS (2004)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2004)
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Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure
Endo, Seiko, Fukahori, Aiko, Tokuhiro, Shinya, Shinagawa, Akira, Walker, Joseph, Yoshihara, Kazutaka, Ishizuka, Hitoshi, Ieiri, Ichiro, Sugiyama, Yuichi
Published in Journal of human genetics (01.08.2012)
Published in Journal of human genetics (01.08.2012)
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Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans
Kitamura, Satoshi, Maeda, Kazuya, Sugiyama, Yuichi
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2008)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.06.2008)
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Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta
Cha, Seok Ho, Sekine, Takashi, Kusuhara, Hiroyuki, Yu, Erkang, Kim, Ju Young, Kim, Do Kyung, Sugiyama, Yuichi, Kanai, Yoshikatsu, Endou, Hitoshi
Published in The Journal of biological chemistry (11.02.2000)
Published in The Journal of biological chemistry (11.02.2000)
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