Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design
Wang, Feng, Jeon, Kyu Ok, Salovich, James M, Macdonald, Jonathan D, Alvarado, Joseph, Gogliotti, Rocco D, Phan, Jason, Olejniczak, Edward T, Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P, Shaw, J Grace, Sai, Jiqing, Rossanese, Olivia W, Tansey, William P, Stauffer, Shaun R, Fesik, Stephen W
Published in Journal of medicinal chemistry (12.07.2018)
Published in Journal of medicinal chemistry (12.07.2018)
Get full text
Journal Article
Discovery of Potent 2‑Aryl-6,7-dihydro‑5H‑pyrrolo[1,2‑a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design
Wang, Feng, Jeon, Kyu Ok, Salovich, James M, Macdonald, Jonathan D, Alvarado, Joseph, Gogliotti, Rocco D, Phan, Jason, Olejniczak, Edward T, Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P, Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W, Tansey, William P, Stauffer, Shaun R, Fesik, Stephen W
Published in Journal of medicinal chemistry (12.07.2018)
Published in Journal of medicinal chemistry (12.07.2018)
Get full text
Journal Article
Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5–MYC Protein–Protein Interaction
Macdonald, Jonathan D, Chacón Simon, Selena, Han, Changho, Wang, Feng, Shaw, J. Grace, Howes, Jennifer E, Sai, Jiqing, Yuh, Joannes P, Camper, Demarco, Alicie, Bethany M, Alvarado, Joseph, Nikhar, Sameer, Payne, William, Aho, Erin R, Bauer, Joshua A, Zhao, Bin, Phan, Jason, Thomas, Lance R, Rossanese, Olivia W, Tansey, William P, Waterson, Alex G, Stauffer, Shaun R, Fesik, Stephen W
Published in Journal of medicinal chemistry (26.12.2019)
Published in Journal of medicinal chemistry (26.12.2019)
Get full text
Journal Article
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy
Nickols, Hilary Highfield, Yuh, Joannes P, Gregory, Karen J, Morrison, Ryan D, Bates, Brittney S, Stauffer, Shaun R, Emmitte, Kyle A, Bubser, Michael, Peng, Weimin, Nedelcovych, Michael T, Thompson, Analisa, Lv, Xiaohui, Xiang, Zixiu, Daniels, J Scott, Niswender, Colleen M, Lindsley, Craig W, Jones, Carrie K, Conn, P Jeffrey
Published in The Journal of pharmacology and experimental therapeutics (01.01.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2016)
Get full text
Journal Article
Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo1,2- aimidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design
Wang, Feng, Jeon, Kyu Ok, Salovich, James M, Macdonald, Jonathan D, Alvarado, Joseph, Gogliotti, Rocco D, Phan, Jason, Olejniczak, Edward T, Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P, Shaw, J Grace, Sai, Jiqing, Rossanese, Olivia W, Tansey, William P, Stauffer, Shaun R, Fesik, Stephen W
Published in Journal of medicinal chemistry (12.07.2018)
Published in Journal of medicinal chemistry (12.07.2018)
Get full text
Journal Article