Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells
Young, Jessica E., Boulanger-Weill, Jonathan, Williams, Daniel A., Woodruff, Grace, Buen, Floyd, Revilla, Arra C., Herrera, Cheryl, Israel, Mason A., Yuan, Shauna H., Edland, Steven D., Goldstein, Lawrence S.B.
Published in Cell stem cell (02.04.2015)
Published in Cell stem cell (02.04.2015)
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Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
Israel, Mason A., Yuan, Shauna H., Bardy, Cedric, Reyna, Sol M., Mu, Yangling, Herrera, Cheryl, Hefferan, Michael P., Van Gorp, Sebastiaan, Nazor, Kristopher L., Boscolo, Francesca S., Carson, Christian T., Laurent, Louise C., Marsala, Martin, Gage, Fred H., Remes, Anne M., Koo, Edward H., Goldstein, Lawrence S. B.
Published in Nature (London) (09.02.2012)
Published in Nature (London) (09.02.2012)
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The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells
Woodruff, Grace, Young, Jessica E., Martinez, Fernando J., Buen, Floyd, Gore, Athurva, Kinaga, Jennifer, Li, Zhe, Yuan, Shauna H., Zhang, Kun, Goldstein, Lawrence S.B.
Published in Cell reports (Cambridge) (27.11.2013)
Published in Cell reports (Cambridge) (27.11.2013)
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The Role of PERK in Understanding Development of Neurodegenerative Diseases
Smedley, Garrett Dalton, Walker, Keenan E., Yuan, Shauna H.
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells
Yuan, Shauna H, Martin, Jody, Elia, Jeanne, Flippin, Jessica, Paramban, Rosanto I, Hefferan, Mike P, Vidal, Jason G, Mu, Yangling, Killian, Rhiannon L, Israel, Mason A, Emre, Nil, Marsala, Silvia, Marsala, Martin, Gage, Fred H, Goldstein, Lawrence S B, Carson, Christian T
Published in PloS one (02.03.2011)
Published in PloS one (02.03.2011)
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A high efficiency precision genome editing method with CRISPR in iPSCs
Singh, Avinash, Smedley, G. Dalton, Rose, Jamee-Grace, Fredriksen, Kristina, Zhang, Ying, Li, Ling, Yuan, Shauna H.
Published in Scientific reports (30.04.2024)
Published in Scientific reports (30.04.2024)
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Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation
Reilly, Patrick, Winston, Charisse N, Baron, Kelsey, Trejo, Margarita, Rockenstein, Edward M, Akers, Johnny C, Kfoury, Najla, Diamond, Marc, Masliah, Eliezer, Rissman, Robert A, Yuan, Shauna H
Published in Neurobiology of disease (01.10.2017)
Published in Neurobiology of disease (01.10.2017)
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Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1
ORDONEZ, M. Paulina, ROBERTS, Elizabeth A, KIDWELL, Chelsea U, YUAN, Shauna H, PLAISTED, Warren C, GOLDSTEIN, Lawrence S. B
Published in Human molecular genetics (15.06.2012)
Published in Human molecular genetics (15.06.2012)
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TOX3 regulates calcium-dependent transcription in neurons
Yuan, Shauna H, Qiu, Zilong, Ghosh, Anirvan
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
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Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons
Podvin, Sonia, Jones, Alexander, Liu, Qing, Aulston, Brent, Mosier, Charles, Ames, Janneca, Winston, Charisse, Lietz, Christopher B, Jiang, Zhenze, O’Donoghue, Anthony J, Ikezu, Tsuneya, Rissman, Robert A, Yuan, Shauna H, Hook, Vivian
Published in ACS omega (25.05.2021)
Published in ACS omega (25.05.2021)
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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
Mertens, Jerome, Herdy, Joseph R., Traxler, Larissa, Schafer, Simon T., Schlachetzki, Johannes C.M., Böhnke, Lena, Reid, Dylan A., Lee, Hyungjun, Zangwill, Dina, Fernandes, Diana P., Agarwal, Ravi K., Lucciola, Raffaella, Zhou-Yang, Lucia, Karbacher, Lukas, Edenhofer, Frank, Stern, Shani, Horvath, Steve, Paquola, Apua C.M., Glass, Christopher K., Yuan, Shauna H., Ku, Manching, Szücs, Attila, Goldstein, Lawrence S.B., Galasko, Douglas, Gage, Fred H.
Published in Cell stem cell (02.09.2021)
Published in Cell stem cell (02.09.2021)
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Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo
Winston, Charisse N, Aulston, Brent, Rockenstein, Edward M, Adame, Anthony, Prikhodko, Olga, Dave, Kishan N, Mishra, Priyanka, Rissman, Robert A, Yuan, Shauna H
Published in Journal of Alzheimer's disease (01.01.2019)
Published in Journal of Alzheimer's disease (01.01.2019)
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A Case of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FET) With Corticobasal Features and Language Deficits
Goodwill, Vanessa, Coughlin, David, Pizzo, Donald, Galasko, Douglas, Hansen, Lawrence A, Yuan, Shauna H, Hiniker, Annie
Published in Journal of neuropathology and experimental neurology (27.09.2021)
Published in Journal of neuropathology and experimental neurology (27.09.2021)
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Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress
Yuan, Shauna H, Hiramatsu, Nobuhiko, Liu, Qing, Sun, Xuehan Victoria, Lenh, David, Chan, Priscilla, Chiang, Karen, Koo, Edward H, Kao, Aimee W, Litvan, Irene, Lin, Jonathan H
Published in Human molecular genetics (15.11.2018)
Published in Human molecular genetics (15.11.2018)
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Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers
Liu, Qing, Waltz, Shannon, Woodruff, Grace, Ouyang, Joe, Israel, Mason A, Herrera, Cheryl, Sarsoza, Floyd, Tanzi, Rudolph E, Koo, Edward H, Ringman, John M, Goldstein, Lawrence S B, Wagner, Steven L, Yuan, Shauna H
Published in JAMA neurology (01.12.2014)
Published in JAMA neurology (01.12.2014)
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Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial
Rafii, Michael S, Sol, Olivier, Mobley, William C, Delpretti, Saskia, Skotko, Brian G, Burke, Anna D, Sabbagh, Marwan N, Yuan, Shauna H, Rissman, Robert A, Pulsifer, Margaret, Evans, Casey, Evans, A Carol, Beth, Gregory, Fournier, Nicolas, Gray, Julian A, Dos Santos, Antonio Melo, Hliva, Valerie, Vukicevic, Marija, Kosco-Vilbois, Marie, Streffer, Johannes, Pfeifer, Andrea, Feldman, Howard H
Published in Archives of neurology (Chicago) (01.06.2022)
Published in Archives of neurology (Chicago) (01.06.2022)
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