Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion
Yu, Yi-Ru, Imrichova, Hana, Wang, Haiping, Chao, Tung, Xiao, Zhengtao, Gao, Min, Rincon-Restrepo, Marcela, Franco, Fabien, Genolet, Raphael, Cheng, Wan-Chen, Jandus, Camilla, Coukos, George, Jiang, Yi-Fan, Locasale, Jason W., Zippelius, Alfred, Liu, Pu-Ste, Tang, Li, Bock, Christoph, Vannini, Nicola, Ho, Ping-Chih
Published in Nature immunology (01.12.2020)
Published in Nature immunology (01.12.2020)
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Journal Article
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity
Di Conza, Giusy, Tsai, Chin-Hsien, Gallart-Ayala, Hector, Yu, Yi-Ru, Franco, Fabien, Zaffalon, Lea, Xie, Xin, Li, Xiaoyun, Xiao, Zhengtao, Raines, Lydia N., Falquet, Maryline, Jalil, Antoine, Locasale, Jason W., Percipalle, Piergiorgio, Masson, David, Huang, Stanley Ching-Cheng, Martinon, Fabio, Ivanisevic, Julijana, Ho, Ping-Chih
Published in Nature immunology (01.11.2021)
Published in Nature immunology (01.11.2021)
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Journal Article
Context‐specific roles of diphthamide deficiency in hepatocellular carcinogenesis
Tu, Wei‐Ling, Chih, Yu‐Chan, Shih, Ya‐Tung, Yu, Yi‐Ru, You, Li‐Ru, Chen, Chun‐Ming
Published in The Journal of pathology (01.10.2022)
Published in The Journal of pathology (01.10.2022)
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Journal Article
A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking units
Cui, Peng-Fei, Zhuang, Wan-Ru, Hu, Xi, Xing, Lei, Yu, Ru-Yi, Qiao, Jian-Bin, He, Yu-Jing, Li, Fangyuan, Ling, Daishun, Jiang, Hu-Lin
Published in Chemical communications (Cambridge, England) (2018)
Published in Chemical communications (Cambridge, England) (2018)
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A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts
Krasny, Lukas, Bland, Philip, Burns, Jessica, Lima, Nadia Carvalho, Harrison, Peter T, Pacini, Laura, Elms, Mark L, Ning, Jian, Martinez, Victor Garcia, Yu, Yi-Ru, Acton, Sophie E, Ho, Ping-Chih, Calvo, Fernando, Swain, Amanda, Howard, Beatrice A, Natrajan, Rachael C, Huang, Paul H
Published in Disease models & mechanisms (14.07.2020)
Published in Disease models & mechanisms (14.07.2020)
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Journal Article
Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome
Yu, Yi-Ru, You, Li-Ru, Yan, Yu-Ting, Chen, Chun-Ming
Published in Human molecular genetics (01.11.2014)
Published in Human molecular genetics (01.11.2014)
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Journal Article
1019 Dysfunctional mitochondria promotes T cell exhaustion and DNA damage responses in CD8+ T cells
Kao, Kung-Chi, Yu, Yi-Ru, Ho, Ping-Chih
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Regulating the Golgi apparatus by co-delivery of a COX-2 inhibitor and Brefeldin A for suppression of tumor metastasis
Yu, Ru-Yi, Xing, Lei, Cui, Peng-Fei, Qiao, Jian-Bin, He, Yu-Jing, Chang, Xin, Zhou, Tian-Jiao, Jin, Qing-Ri, Jiang, Hu-Lin, Xiao, Yanyu
Published in Biomaterials science (01.08.2018)
Published in Biomaterials science (01.08.2018)
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Journal Article
Silencing miRNA-324-3p protects against cerebral ischemic injury via regulation of the GATA2/A1R axis
Zhang, An-Qi, Wang, Lu, Wang, Yi-Xiu, Hong, Shan-Shan, Zhong, Yu-Shan, Yu, Ru-Yi, Wu, Xin-Lu, Zhou, Bing-Bing, Yu, Qi-Min, Fu, Hai-Feng, Chen, Shuang-Dong, Mo, Yun-Chang, Dai, Qin-Xue, Wang, Jun-Lu
Published in Neural regeneration research (01.11.2022)
Published in Neural regeneration research (01.11.2022)
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Journal Article
836 A novel PD-L1 antibody-IL10 fusion protein, PTL011, exhibits synergized therapeutic effect in hepatocellular carcinoma mouse model
Tsai, Chin-Hsien, Tzeng, Sheue-Fen, Yu, Yi-Ru, Hsiao, Huey-Wen, Park, Jaeoh, Koni, Pandelakis, Chen, Hung-Kai, Kandalaft, Lana, Lengerke, Claudia, Ho, Ping-Chih
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
1401 PLT012, a monoclonal antibody targeting CD36, unleashes anti-tumor immunity via metabolic reprogramming in tumor microenvironment
Yu, Yi-Ru, Tsai, Chin-Hsien, Hsiao, Huey-Wen, Park, Jaeoh, Koni, Pandelakis, Chen, Hung-Kai, Kandalaft, Lana, Lengerke, Claudia
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
514 Disturbed Mitochondrial Dynamics Rewire the Epigenetic Program for CD8+ TIL Exhaustion
Yu, Yi-Ru, Wang, Haiping, Franco, Fabien, Ho, Ping-Chih
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Metabolic and epigenetic regulation of T-cell exhaustion
Franco, Fabien, Jaccard, Alison, Romero, Pedro, Yu, Yi-Ru, Ho, Ping-Chih
Published in Nature metabolism (01.10.2020)
Published in Nature metabolism (01.10.2020)
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Journal Article
Metabolic programs tailor T cell immunity in viral infection, cancer, and aging
Møller, Sofie Hedlund, Hsueh, Pei-Chun, Yu, Yi-Ru, Zhang, Lianjun, Ho, Ping-Chih
Published in Cell metabolism (01.03.2022)
Published in Cell metabolism (01.03.2022)
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Journal Article
The Wilms’ tumor suppressor Wt1 regulates Coronin 1B expression in the epicardium
Hsu, Wen-Hsin, Yu, Yi-Ru, Hsu, Shih-Han, Yu, Wan-Chun, Chu, Yu-Hsuan, Chen, Yin-Jui, Chen, Chun-Ming, You, Li-Ru
Published in Experimental cell research (10.06.2013)
Published in Experimental cell research (10.06.2013)
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Journal Article
Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis
Ma, Min, Ghosh, Soumitra, Tavernari, Daniele, Katarkar, Atul, Clocchiatti, Andrea, Mazzeo, Luigi, Samarkina, Anastasia, Epiney, Justine, Yu, Yi-Ru, Ho, Ping-Chih, Levesque, Mitchell P, Özdemir, Berna C, Ciriello, Giovanni, Dummer, Reinhard, Dotto, G Paolo
Published in The Journal of experimental medicine (01.02.2021)
Published in The Journal of experimental medicine (01.02.2021)
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Journal Article
Immunoediting instructs tumor metabolic reprogramming to support immune evasion
Tsai, Chin-Hsien, Chuang, Yu-Ming, Li, Xiaoyun, Yu, Yi-Ru, Tzeng, Sheue-Fen, Teoh, Shao Thing, Lindblad, Katherine E., Di Matteo, Mario, Cheng, Wan-Chen, Hsueh, Pei-Chun, Kao, Kung-Chi, Imrichova, Hana, Duan, Likun, Gallart-Ayala, Hector, Hsiao, Pei-Wen, Mazzone, Massimiliano, Ivanesevic, Julijana, Liu, Xiaojing, de Visser, Karin E., Lujambio, Amaia, Lunt, Sophia Y., Kaech, Susan M., Ho, Ping-Chih
Published in Cell metabolism (03.01.2023)
Published in Cell metabolism (03.01.2023)
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Journal Article
Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems
Girotra, Mukul, Chiang, Yi-Hsuan, Charmoy, Melanie, Ginefra, Pierpaolo, Hope, Helen Carrasco, Bataclan, Charles, Yu, Yi-Ru, Schyrr, Frederica, Franco, Fabien, Geiger, Hartmut, Cherix, Stephane, Ho, Ping-Chih, Naveiras, Olaia, Auwerx, Johan, Held, Werner, Vannini, Nicola
Published in Nature aging (01.09.2023)
Published in Nature aging (01.09.2023)
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