A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
Ding, Ning, Yu, Ruth T., Subramaniam, Nanthakumar, Sherman, Mara H., Wilson, Caroline, Rao, Renuka, Leblanc, Mathias, Coulter, Sally, He, Mingxiao, Scott, Christopher, Lau, Sue L., Atkins, Annette R., Barish, Grant D., Gunton, Jenny E., Liddle, Christopher, Downes, Michael, Evans, Ronald M.
Published in Cell (25.04.2013)
Published in Cell (25.04.2013)
Get full text
Journal Article
Insights into Negative Regulation by the Glucocorticoid Receptor from Genome-wide Profiling of Inflammatory Cistromes
Uhlenhaut, N. Henriette, Barish, Grant D., Yu, Ruth T., Downes, Michael, Karunasiri, Malith, Liddle, Christopher, Schwalie, Petra, Hübner, Norbert, Evans, Ronald M.
Published in Molecular cell (10.01.2013)
Published in Molecular cell (10.01.2013)
Get full text
Journal Article
Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
Mihaylova, Maria M., Vasquez, Debbie S., Ravnskjaer, Kim, Denechaud, Pierre-Damien, Yu, Ruth T., Alvarez, Jacqueline G., Downes, Michael, Evans, Ronald M., Montminy, Marc, Shaw, Reuben J.
Published in Cell (13.05.2011)
Published in Cell (13.05.2011)
Get full text
Journal Article
FXR Regulates Intestinal Cancer Stem Cell Proliferation
Fu, Ting, Coulter, Sally, Yoshihara, Eiji, Oh, Tae Gyu, Fang, Sungsoon, Cayabyab, Fritz, Zhu, Qiyun, Zhang, Tong, Leblanc, Mathias, Liu, Sihao, He, Mingxiao, Waizenegger, Wanda, Gasser, Emanuel, Schnabl, Bernd, Atkins, Annette R., Yu, Ruth T., Knight, Rob, Liddle, Christopher, Downes, Michael, Evans, Ronald M.
Published in Cell (21.02.2019)
Published in Cell (21.02.2019)
Get full text
Journal Article
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Shalapour, Shabnam, Lin, Xue-Jia, Bastian, Ingmar N, Brain, John, Burt, Alastair D, Aksenov, Alexander A, Vrbanac, Alison F, Li, Weihua, Perkins, Andres, Matsutani, Takaji, Zhong, Zhenyu, Dhar, Debanjan, Navas-Molina, Jose A, Xu, Jun, Loomba, Rohit, Downes, Michael, Yu, Ruth T, Evans, Ronald M, Dorrestein, Pieter C, Knight, Rob, Benner, Christopher, Anstee, Quentin M, Karin, Michael
Published in Nature (London) (16.11.2017)
Published in Nature (London) (16.11.2017)
Get full text
Journal Article
Immune-evasive human islet-like organoids ameliorate diabetes
Yoshihara, Eiji, O'Connor, Carolyn, Gasser, Emanuel, Wei, Zong, Oh, Tae Gyu, Tseng, Tiffany W, Wang, Dan, Cayabyab, Fritz, Dai, Yang, Yu, Ruth T, Liddle, Christopher, Atkins, Annette R, Downes, Michael, Evans, Ronald M
Published in Nature (London) (22.10.2020)
Published in Nature (London) (22.10.2020)
Get full text
Journal Article
ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells
Yoshihara, Eiji, Wei, Zong, Lin, Chun Shi, Fang, Sungsoon, Ahmadian, Maryam, Kida, Yasuyuki, Tseng, Tiffany, Dai, Yang, Yu, Ruth T., Liddle, Christopher, Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Published in Cell metabolism (12.04.2016)
Published in Cell metabolism (12.04.2016)
Get full text
Journal Article
BRD4 is a novel therapeutic target for liver fibrosis
Ding, Ning, Hah, Nasun, Yu, Ruth T., Sherman, Mara H., Benner, Chris, Leblanc, Mathias, He, Mingxiao, Liddle, Christopher, Downes, Michael, Evans, Ronald M.
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (22.12.2015)
Get full text
Journal Article
Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice
Hartmann, Phillipp, Hochrath, Katrin, Horvath, Angela, Chen, Peng, Seebauer, Caroline T., Llorente, Cristina, Wang, Lirui, Alnouti, Yazen, Fouts, Derrick E., Stärkel, Peter, Loomba, Rohit, Coulter, Sally, Liddle, Christopher, Yu, Ruth T., Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Downes, Michael, Evans, Ronald M., Brenner, David A., Schnabl, Bernd
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Get full text
Journal Article
Depletion of fat-resident Treg cells prevents age-associated insulin resistance
Bapat, Sagar P, Myoung Suh, Jae, Fang, Sungsoon, Liu, Sihao, Zhang, Yang, Cheng, Albert, Zhou, Carmen, Liang, Yuqiong, LeBlanc, Mathias, Liddle, Christopher, Atkins, Annette R, Yu, Ruth T, Downes, Michael, Evans, Ronald M, Zheng, Ye
Published in Nature (London) (03.12.2015)
Published in Nature (London) (03.12.2015)
Get full text
Journal Article
ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency
Kida, Yasuyuki S., Kawamura, Teruhisa, Wei, Zong, Sogo, Takahiro, Jacinto, Sandra, Shigeno, Asako, Kushige, Hiroko, Yoshihara, Eiji, Liddle, Christopher, Ecker, Joseph R., Yu, Ruth T., Atkins, Annette R., Downes, Michael, Evans, Ronald M.
Published in Cell stem cell (07.05.2015)
Published in Cell stem cell (07.05.2015)
Get full text
Journal Article
Metabolic control of regulatory T cell (Treg) survival and function by Lkb1
He, Nanhai, Fan, Weiwei, Henriquez, Brian, Yu, Ruth T., Atkins, Annette R., Liddle, Christopher, Zheng, Ye, Downes, Michael, Evans, Ronald M.
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
Get full text
Journal Article
Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
Fang, Sungsoon, Suh, Jae Myoung, Reilly, Shannon M, Yu, Elizabeth, Osborn, Olivia, Lackey, Denise, Yoshihara, Eiji, Perino, Alessia, Jacinto, Sandra, Lukasheva, Yelizaveta, Atkins, Annette R, Khvat, Alexander, Schnabl, Bernd, Yu, Ruth T, Brenner, David A, Coulter, Sally, Liddle, Christopher, Schoonjans, Kristina, Olefsky, Jerrold M, Saltiel, Alan R, Downes, Michael, Evans, Ronald M
Published in Nature medicine (01.02.2015)
Published in Nature medicine (01.02.2015)
Get full text
Journal Article
A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis
Oh, Tae Gyu, Kim, Susy M., Caussy, Cyrielle, Fu, Ting, Guo, Jian, Bassirian, Shirin, Singh, Seema, Madamba, Egbert V., Bettencourt, Ricki, Richards, Lisa, Yu, Ruth T., Atkins, Annette R., Huan, Tao, Brenner, David A., Sirlin, Claude B., Downes, Michael, Evans, Ronald M., Loomba, Rohit
Published in Cell metabolism (03.11.2020)
Published in Cell metabolism (03.11.2020)
Get full text
Journal Article
Vitamin D Switches BAF Complexes to Protect β Cells
Wei, Zong, Yoshihara, Eiji, He, Nanhai, Hah, Nasun, Fan, Weiwei, Pinto, Antonio F.M., Huddy, Timothy, Wang, Yuhao, Ross, Brittany, Estepa, Gabriela, Dai, Yang, Ding, Ning, Sherman, Mara H., Fang, Sungsoon, Zhao, Xuan, Liddle, Christopher, Atkins, Annette R., Yu, Ruth T., Downes, Michael, Evans, Ronald M.
Published in Cell (17.05.2018)
Published in Cell (17.05.2018)
Get full text
Journal Article
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
CHO, Han, XUAN ZHAO, LIDDLE, Christopher, AUWERX, Johan, DOWNES, Michael, PANDA, Satchidananda, EVANS, Ronald M, HATORI, Megumi, YU, Ruth T, BARISH, Grant D, LAM, Michael T, CHONG, Ling-Wa, DITACCHIO, Luciano, ATKINS, Annette R, GLASS, Christopher K
Published in Nature (London) (03.05.2012)
Published in Nature (London) (03.05.2012)
Get full text
Journal Article
β3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity
Valentine, Joseph M, Ahmadian, Maryam, Keinan, Omer, Abu-Odeh, Mohammad, Zhao, Peng, Zhou, Xin, Keller, Mark P, Gao, Hui, Yu, Ruth T, Liddle, Christopher, Downes, Michael, Zhang, Jin, Lusis, Aldons J, Attie, Alan D, Evans, Ronald M, Rydén, Mikael, Saltiel, Alan R
Published in The Journal of clinical investigation (18.01.2022)
Published in The Journal of clinical investigation (18.01.2022)
Get full text
Journal Article
PPARδ Promotes Running Endurance by Preserving Glucose
Fan, Weiwei, Waizenegger, Wanda, Lin, Chun Shi, Sorrentino, Vincenzo, He, Ming-Xiao, Wall, Christopher E., Li, Hao, Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Auwerx, Johan, Downes, Michael, Evans, Ronald M.
Published in Cell metabolism (02.05.2017)
Published in Cell metabolism (02.05.2017)
Get full text
Journal Article