Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2 -deficient Mesothelioma
Tang, Tracy T, Konradi, Andrei W, Feng, Ying, Peng, Xiao, Ma, Mingyue, Li, Jian, Yu, Fa-Xing, Guan, Kun-Liang, Post, Leonard
Published in Molecular cancer therapeutics (01.06.2021)
Published in Molecular cancer therapeutics (01.06.2021)
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Differential regulation of mTORC1 by leucine and glutamine
Jewell, Jenna L., Kim, Young Chul, Russell, Ryan C., Yu, Fa-Xing, Park, Hyun Woo, Plouffe, Steven W., Tagliabracci, Vincent S., Guan, Kun-Liang
Published in Science (American Association for the Advancement of Science) (09.01.2015)
Published in Science (American Association for the Advancement of Science) (09.01.2015)
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A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
Moroishi, Toshiro, Park, Hyun Woo, Qin, Baodong, Chen, Qian, Meng, Zhipeng, Plouffe, Steven W, Taniguchi, Koji, Yu, Fa-Xing, Karin, Michael, Pan, Duojia, Guan, Kun-Liang
Published in Genes & development (15.06.2015)
Published in Genes & development (15.06.2015)
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Two Hippo signaling modules orchestrate liver size and tumorigenesis
Qi, Sixian, Zhong, Zhenxing, Zhu, Yuwen, Wang, Yebin, Ma, Mingyue, Wang, Yu, Liu, Xincheng, Jin, Ruxin, Jiao, Zhihan, Zhu, Rui, Sha, Zhao, Dang, Kyvan, Liu, Ying, Lim, Dae‐Sik, Mao, Junhao, Zhang, Lei, Yu, Fa‐Xing
Published in The EMBO journal (01.06.2023)
Published in The EMBO journal (01.06.2023)
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Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
Mo, Jung-Soon, Yu, Fa-Xing, Gong, Rui, Brown, Joan Heller, Guan, Kun-Liang
Published in Genes & development (01.10.2012)
Published in Genes & development (01.10.2012)
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MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
Meng, Zhipeng, Moroishi, Toshiro, Mottier-Pavie, Violaine, Plouffe, Steven W, Hansen, Carsten G, Hong, Audrey W, Park, Hyun Woo, Mo, Jung-Soon, Lu, Wenqi, Lu, Shicong, Flores, Fabian, Yu, Fa-Xing, Halder, Georg, Guan, Kun-Liang
Published in Nature communications (05.10.2015)
Published in Nature communications (05.10.2015)
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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Yu, Fa-Xing, Zhao, Bin, Panupinthu, Nattapon, Jewell, Jenna L., Lian, Ian, Wang, Lloyd H., Zhao, Jiagang, Yuan, Haixin, Tumaneng, Karen, Li, Hairi, Fu, Xiang-Dong, Mills, Gordon B., Guan, Kun-Liang
Published in Cell (17.08.2012)
Published in Cell (17.08.2012)
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Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis
Fu, Lina, Hu, Yuqiong, Song, Moshi, Liu, Zunpeng, Zhang, Weiqi, Yu, Fa-Xing, Wu, Jun, Wang, Si, Izpisua Belmonte, Juan Carlos, Chan, Piu, Qu, Jing, Tang, Fuchou, Liu, Guang-Hui
Published in PLoS biology (01.04.2019)
Published in PLoS biology (01.04.2019)
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Proteolytic activation of angiomotin by DDI2 promotes angiogenesis
Wang, Yu, Zhu, Yuwen, Wang, Yebin, Chang, Yue, Geng, Fang, Ma, Mingyue, Gu, Yuan, Yu, Aijuan, Zhu, Rui, Yu, Pengcheng, Sha, Zhao, Qi, Sixian, Li, Jian, Zhao, Wencao, Pan, Weijun, Zhang, Ruilin, Yu, Fa‐Xing
Published in The EMBO journal (01.08.2023)
Published in The EMBO journal (01.08.2023)
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Journal Article
Hippo Pathway Regulation of Gastrointestinal Tissues
Yu, Fa-Xing, Meng, Zhipeng, Plouffe, Steven W, Guan, Kun-Liang
Published in Annual review of physiology (01.01.2015)
Published in Annual review of physiology (01.01.2015)
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STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis
Shen, Ying, Wang, Xiaohong, Liu, Yi, Singhal, Mahak, Gürkaşlar, Can, Valls, Aida Freire, Lei, Yi, Hu, Wenjie, Schermann, Géza, Adler, Heike, Yu, Fa-Xing, Fischer, Tamás, Zhu, Yi, Augustin, Hellmut G, Schmidt, Thomas, de Almodóvar, Carmen Ruiz
Published in Science signaling (07.12.2021)
Published in Science signaling (07.12.2021)
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USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer
Pan, Beiqing, Yang, Yi, Li, Jian, Wang, Yu, Fang, Chuantao, Yu, Fa-Xing, Xu, Yanhui
Published in Protein & cell (01.02.2020)
Published in Protein & cell (01.02.2020)
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Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
Yu, Fa-Xing, Zhang, Yifan, Park, Hyun Woo, Jewell, Jenna L, Chen, Qian, Deng, Yaoting, Pan, Duojia, Taylor, Susan S, Lai, Zhi-Chun, Guan, Kun-Liang
Published in Genes & development (01.06.2013)
Published in Genes & development (01.06.2013)
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Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis
Zhou, Beiyun, Flodby, Per, Luo, Jiao, Castillo, Dan R, Liu, Yixin, Yu, Fa-Xing, McConnell, Alicia, Varghese, Bino, Li, Guanglei, Chimge, Nyam-Osor, Sunohara, Mitsuhiro, Koss, Michael N, Elatre, Wafaa, Conti, Peter, Liebler, Janice M, Yang, Chenchen, Marconett, Crystal N, Laird-Offringa, Ite A, Minoo, Parviz, Guan, Kunliang, Stripp, Barry R, Crandall, Edward D, Borok, Zea
Published in The Journal of clinical investigation (01.03.2018)
Published in The Journal of clinical investigation (01.03.2018)
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