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Published in Clinical science (1979) (01.01.2010)
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dipeptidyl peptidase IV family in cancer and cell biology
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High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)
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Published in Biochemical pharmacology (01.09.2014)
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Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen
Cheung, Leanna, Yu, Denise M.T., Neiron, Zillan, Failes, Tim W., Arndt, Greg M., Fletcher, Jamie I.
Published in Biochemical pharmacology (01.02.2015)
Published in Biochemical pharmacology (01.02.2015)
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Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas
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Published in Nature communications (12.02.2021)
Published in Nature communications (12.02.2021)
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Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
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Published in Science translational medicine (30.01.2019)
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MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells
Gana, Christine C., Hanssen, Kimberley M., Yu, Denise M.T., Flemming, Claudia L., Wheatley, Madeleine S., Conseil, Gwenaëlle, Cole, Susan P.C., Norris, Murray D., Haber, Michelle, Fletcher, Jamie I.
Published in Biochemical pharmacology (01.10.2019)
Published in Biochemical pharmacology (01.10.2019)
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Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition
Khan, Aaminah, Valli, Emanuele, Lam, Hayley, Scott, David A., Murray, Jayne, Hanssen, Kimberley M., Eden, Georgina, Gamble, Laura D., Pandher, Rupinder, Flemming, Claudia L., Allan, Sophie, Osterman, Andrei L., Haber, Michelle, Norris, Murray D., Fletcher, Jamie I., Yu, Denise M. T.
Published in Oncogene (23.04.2020)
Published in Oncogene (23.04.2020)
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GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators
Hanssen, Kimberley M., Wheatley, Madeleine S., Yu, Denise M. T., Conseil, Gwenaëlle, Norris, Murray D., Haber, Michelle, Cole, Susan P. C., Fletcher, Jamie I.
Published in The FEBS journal (01.07.2022)
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High level, tissue-specific expression of a modified calcitonin/calcitonin gene-related peptide promoter in a human medullary thyroid carcinoma cell line
Messina, Marinella, Yu, Denise M.T, Learoyd, Diana L, Both, Gerald W, Molloy, Peter L, Robinson, Bruce G
Published in Molecular and cellular endocrinology (01.06.2000)
Published in Molecular and cellular endocrinology (01.06.2000)
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CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth
Huynh, Tony, Murray, Jayne, Flemming, Claudia L., Kamili, Alvin, Hofmann, Ute, Cheung, Leanna, Roundhill, Elizabeth A., Yu, Denise M.T., Webber, Hannah T., Schwab, Matthias, Henderson, Michelle J., Haber, Michelle, Norris, Murray D., Fletcher, Jamie I.
Published in Biochemical pharmacology (01.02.2020)
Published in Biochemical pharmacology (01.02.2020)
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ABC Transporters and Neuroblastoma
Yu, Denise M T, Huynh, Tony, Truong, Alan M, Haber, Michelle, Norris, Murray D
Published in ABC Transporters and Cancer (2015)
Published in ABC Transporters and Cancer (2015)
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Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo
Murray, Jayne, Valli, Emanuele, Yu, Denise M.T., Truong, Alan M., Gifford, Andrew J., Eden, Georgina L., Gamble, Laura D., Hanssen, Kimberley M., Flemming, Claudia L., Tan, Alvin, Tivnan, Amanda, Allan, Sophie, Saletta, Federica, Cheung, Leanna, Ruhle, Michelle, Schuetz, John D., Henderson, Michelle J., Byrne, Jennifer A., Norris, Murray D., Haber, Michelle, Fletcher, Jamie I.
Published in European journal of cancer (1990) (01.09.2017)
Published in European journal of cancer (1990) (01.09.2017)
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Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality
Gall, Margaret G, Chen, Yiqian, Vieira de Ribeiro, Ana Julia, Zhang, Hui, Bailey, Charles G, Spielman, Derek S, Yu, Denise M T, Gorrell, Mark D
Published in PloS one (06.11.2013)
Published in PloS one (06.11.2013)
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The pro‐fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride‐induced experimental liver injury
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Published in Immunology and cell biology (01.05.2017)
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MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
Xue, Chengyuan, Yu, Denise M T, Gherardi, Samuele, Koach, Jessica, Milazzo, Giorgio, Gamble, Laura, Liu, Bing, Valli, Emanuele, Russell, Amanda J, London, Wendy B, Liu, Tao, Cheung, Belamy B, Marshall, Glenn M, Perini, Giovanni, Haber, Michelle, Norris, Murray D
Published in Oncotarget (23.08.2016)
Published in Oncotarget (23.08.2016)
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Published in World journal of gastroenterology : WJG (21.05.2013)
Published in World journal of gastroenterology : WJG (21.05.2013)
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Characterization of Cysteine Cathepsin Expression in the Central Nervous System of Aged Wild-Type and Cathepsin-Deficient Mice
Yu, Denise M. T., Dauth, Stephanie, Margineanu, Michael B., Snetkova, Valentina, Rehders, Maren, Jordans, Silvia, Brix, Klaudia
Published in Applied sciences (01.03.2022)
Published in Applied sciences (01.03.2022)
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