Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)
Bittenbinder, Mátyás A, Zdenek, Christina N, Op den Brouw, Bianca, Youngman, Nicholas J, Dobson, James S, Naude, Arno, Vonk, Freek J, Fry, Bryan G
Published in Toxins (04.12.2018)
Published in Toxins (04.12.2018)
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Journal Article
Efficacy and Limitations of Chemically Diverse Small-Molecule Enzyme-Inhibitors against the Synergistic Coagulotoxic Activities of Bitis Viper Venoms
Youngman, Nicholas J, Lewin, Matthew R, Carter, Rebecca, Naude, Arno, Fry, Bryan G
Published in Molecules (Basel, Switzerland) (07.03.2022)
Published in Molecules (Basel, Switzerland) (07.03.2022)
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Journal Article
Differential Antivenom and Small-Molecule Inhibition of Novel Coagulotoxic Variations in Atropoides, Cerrophidion, Metlapilcoatlus, and Porthidium American Viperid Snake Venoms
Jones, Lee, Youngman, Nicholas J., Neri-Castro, Edgar, Guadarrama-Martínez, Alid, Lewin, Matthew R., Carter, Rebecca, Frank, Nathaniel, Fry, Bryan G.
Published in Toxins (26.07.2022)
Published in Toxins (26.07.2022)
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Journal Article
A Taxon-Specific and High-Throughput Method for Measuring Ligand Binding to Nicotinic Acetylcholine Receptors
Zdenek, Christina N, Harris, Richard J, Kuruppu, Sanjaya, Youngman, Nicholas J, Dobson, James S, Debono, Jordan, Khan, Muzaffar, Smith, Ian, Yarski, Mike, Harrich, David, Sweeney, Charlotte, Dunstan, Nathan, Allen, Luke, Fry, Bryan G
Published in Toxins (16.10.2019)
Published in Toxins (16.10.2019)
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Journal Article
Assessing the Binding of Venoms from Aquatic Elapids to the Nicotinic Acetylcholine Receptor Orthosteric Site of Different Prey Models
Harris, Richard J, Youngman, Nicholas J, Zdenek, Christina N, Huynh, Tam M, Nouwens, Amanda, Hodgson, Wayne C, Harrich, David, Dunstan, Nathan, Portes-Junior, José A, Fry, Bryan G
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Journal Article
Venomous Landmines: Clinical Implications of Extreme Coagulotoxic Diversification and Differential Neutralization by Antivenom of Venoms within the Viperid Snake Genus Bitis
Youngman, Nicholas J, Debono, Jordan, Dobson, James S, Zdenek, Christina N, Harris, Richard J, Op den Brouw, Bianca, Coimbra, Francisco C P, Naude, Arno, Coster, Kristian, Sundman, Eric, Braun, Ralph, Hendrikx, Iwan, Fry, Bryan G
Published in Toxins (19.07.2019)
Published in Toxins (19.07.2019)
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Journal Article
A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms
Grashof, Dwin, Zdenek, Christina N, Dobson, James S, Youngman, Nicholas J, Coimbra, Francisco, Benard-Valle, Melisa, Alagon, Alejandro, Fry, Bryan G
Published in Toxins (30.01.2020)
Published in Toxins (30.01.2020)
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Journal Article
Anticoagulant activity of black snake (Elapidae: Pseudechis) venoms: Mechanisms, potency, and antivenom efficacy
Zdenek, Christina N., Youngman, Nicholas J., Hay, Chris, Dobson, James, Dunstan, Nathan, Allen, Luke, Milanovic, Leontina, Fry, Bryan G.
Published in Toxicology letters (15.09.2020)
Published in Toxicology letters (15.09.2020)
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Journal Article
Getting stoned: Characterisation of the coagulotoxic and neurotoxic effects of reef stonefish (Synanceia verrucosa) venom
Harris, Richard J., Youngman, Nicholas J., Chan, Weili, Bosmans, Frank, Cheney, Karen L., Fry, Bryan G.
Published in Toxicology letters (01.08.2021)
Published in Toxicology letters (01.08.2021)
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Journal Article
The relative efficacy of chemically diverse small-molecule enzyme-inhibitors against anticoagulant activities of Black Snake (Pseudechis spp.) venoms
Chowdhury, Abhinandan, Youngman, Nicholas J., Liu, Jiaojiao, Lewin, Matthew R., Carter, Rebecca W., Fry, Bryan G.
Published in Toxicology letters (01.08.2022)
Published in Toxicology letters (01.08.2022)
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Journal Article
Cloud serpent coagulotoxicity: The biochemical mechanisms underpinning the anticoagulant actions of Mixcoatlus and Ophryacus venoms
Youngman, Nicholas J., Carlsson, Demi J., Jones, Lee, Neri-Castro, Edgar, Alagón, Alejandro, Fry, Bryan G.
Published in Toxicon (Oxford) (01.05.2022)
Published in Toxicon (Oxford) (01.05.2022)
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Journal Article
Varespladib (LY315920) neutralises phospholipase A2 mediated prothrombinase-inhibition induced by Bitis snake venoms
Youngman, Nicholas J., Walker, Andrew, Naude, Arno, Coster, Kristian, Sundman, Eric, Fry, Bryan G.
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.10.2020)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.10.2020)
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Journal Article
Untangling interactions between Bitis vipers and their prey using coagulotoxicity against diverse vertebrate plasmas
Youngman, Nicholas J., Llinas, Joshua, Haworth, Mark, Gillett, Amber, Jones, Lee, Walker, Andrew A., Fry, Bryan G.
Published in Toxicon (Oxford) (01.09.2022)
Published in Toxicon (Oxford) (01.09.2022)
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Journal Article
Utilising venom activity to infer dietary composition of the Kenyan horned viper (Bitis worthingtoni)
Youngman, Nicholas J., Chowdhury, Abhinandan, Zdenek, Christina N., Coster, Kristian, Sundman, Eric, Braun, Ralph, Fry, Bryan G.
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.02.2021)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.02.2021)
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Journal Article
Trimeresurus albolabris snakebite treatment implications arising from ontogenetic venom comparisons of anticoagulant function, and antivenom efficacy
Bourke, Lachlan A., Youngman, Nicholas J., Zdenek, Christina N., op den Brouw, Bianca, Violette, Aude, Fourmy, Rudy, Fry, Bryan G.
Published in Toxicology letters (01.07.2020)
Published in Toxicology letters (01.07.2020)
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Journal Article
Differential coagulotoxic and neurotoxic venom activity from species of the arboreal viperid snake genus Bothriechis (palm-pitvipers)
Youngman, Nicholas J., Peng, Yin-Hsuan, Harris, Richard J., Jones, Lee, Llinas, Joshua, Haworth, Mark, Gillett, Amber, Fry, Bryan G.
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.06.2022)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.06.2022)
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Journal Article
Anticoagulant Micrurus venoms: Targets and neutralization
Dashevsky, Daniel, Bénard-Valle, Melisa, Neri-Castro, Edgar, Youngman, Nicholas J., Zdenek, Christina N., Alagón, Alejandro, Portes-Junior, José A., Frank, Nathaniel, Fry, Bryan G.
Published in Toxicology letters (01.02.2021)
Published in Toxicology letters (01.02.2021)
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Journal Article
Clinical implications of convergent procoagulant toxicity and differential antivenom efficacy in Australian elapid snake venoms
Zdenek, Christina N., den Brouw, Bianca op, Dashevsky, Daniel, Gloria, Alexandra, Youngman, Nicholas J., Watson, Ebony, Green, Patrick, Hay, Chris, Dunstan, Nathan, Allen, Luke, Fry, Bryan G.
Published in Toxicology letters (01.11.2019)
Published in Toxicology letters (01.11.2019)
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Journal Article
Widespread and Differential Neurotoxicity in Venoms from the Bitis Genus of Viperid Snakes
Youngman, Nicholas J., Harris, Richard J., Huynh, Tam M., Coster, Kristian, Sundman, Eric, Braun, Ralph, Naude, Arno, Hodgson, Wayne C., Fry, Bryan G.
Published in Neurotoxicity research (01.06.2021)
Published in Neurotoxicity research (01.06.2021)
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Journal Article