Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cells
Hong, Seung-Woo, Shin, Jae-Sik, Moon, Jai-Hee, Jung, Soo-A, Koh, Dong-In, Ryu, Yeaseong, Park, Yoon Sun, Kim, Do Yeon, Park, Sang-Soo, Hong, Jun Ki, Kim, Eun Ho, Kim, Mi Jin, Jeong, Hong-Rae, Bae, In Hwan, Ahn, Young-Gil, Suh, Kwee Hyun, Cho, Ig-Jun, Kang, Jong-Soon, Hong, Yong Sang, Lee, Jung Shin, Jin, Dong-Hoon, Kim, Tae Won
Published in Investigational new drugs (01.12.2020)
Published in Investigational new drugs (01.12.2020)
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Abstract 1142: A novel and potent EZH1/2 dual inhibitor, HM97662, demonstrates antitumor activity in malignant tumors
Jung, Seung Hyun, Hong, DongJin, Hwang, Jiyoung, Park, Somin, Byun, Jooyun, Lee, Miyoung, Koo, Kyounghwa, Lee, Gunwoo, Kim, Yu-Yon, Bak, Yesol, Ahn, Young Gil, Kim, YoungHoon, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Synthesis and biological evaluation of novel thienopyrimidine derivatives as diacylglycerol acyltransferase 1 (DGAT-1) inhibitors
Hong, Dong Jin, Jung, Seung Hyun, Kim, Jisook, Jung, Danbee, Ahn, Young Gil, Suh, Kwee Hyun, Min, Kyung Hoon
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel
Kwak, Jin-Oh, Lee, Sung Hee, Lee, Gwan Sun, Kim, Maeng Sup, Ahn, Young-Gil, Lee, Ji Hyun, Kim, So Won, Kim, Kyung Hwan, Lee, Min Goo
Published in European journal of pharmacology (10.02.2010)
Published in European journal of pharmacology (10.02.2010)
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Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice
Lee, Sang-Hyun, Kim, YoungSoo, Kim, Hye Yun, Kim, Young Hoon, Kim, Maeng Sup, Kong, Jae Yang, Lee, Mun-Han, Kim, Dong Jin, Ahn, Young Gil
Published in PloS one (23.04.2014)
Published in PloS one (23.04.2014)
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Discovery of 2,6-Naphthyridine Analogues as Selective FGFR4 Inhibitors for Hepatocellular Carcinoma
Oh, Heesook, Kim, Jisook, Jung, Seung Hyun, Ha, Tae Hee, Ahn, Young Gil, Nam, Gibeom, Moon, Kyeongwon, Singh, Pargat, Kim, In Su
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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A Novel and Potent EZH1/2 Dual Inhibitor, HM97662 Demonstrated a Wide Spectrum of Therapeutic Potential for Hematological Malignancies
Jung, Seung Hyun, Byun, Jooyun, Kim, Yu-Yon, Han, Seon Yeong, Lee, Miyoung, Lee, Gunwoo, Park, Junghwa, Ahn, Young Gil, Kim, Young Hoon, Suh, Kwee Hyun, Koh, Youngil
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model
Kim, Yu-Yon, Park, Hyunjin, Song, Taehun, Choi, Kyungjin, Dolton, Michael, Mao, Jialin, Kim, Jisook, Ahn, Young Gil, Suh, Kwee Hyun, Kim, Young Hoon
Published in Clinical & experimental metastasis (01.04.2023)
Published in Clinical & experimental metastasis (01.04.2023)
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Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
Jeon, Jiyoung, Jang, Sun Young, Kwak, Eun Joo, Lee, Sun Hoe, Byun, Joo-Yun, Kim, Yu-Yon, Ahn, Young Gil, Singh, Pargat, Moon, Kyeongwon, Kim, In Su
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Abstract 1474: Antitumor activity of belvarafenib in melanoma brain metastasis and NRAS mutation melanoma models
Bae, Inhwan, Kim, Yu-Yon, Kim, Jisook, Park, Hyunjin, Song, Taehyun, Byun, Joo-Yun, Lim, Semi, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1257: HM43239, a novel FLT3 inhibitor, has the potential to inhibit mutations resistant to FLT3 inhibitors
Bae, Inhwan, Choi, Jaeyul, Song, Jiyoung, Byun, Joo-Yun, Lee, Eunyoung, Song, Taehun, Kim, Yu-Yon, Bak, Yesol, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1704: Discovery and characterization of a novel triple A1/A2a/A2b adenosine receptor antagonist for cancer immunotherapy
Jang, Sunyoung, Jun, Seunah, Lee, Hosun, Lee, Yongtaek, Byun, Joo-Yun, Park, Junghwa, Kim, Yu-Yon, Ahn, Young Gil, Kim, YoungHoon, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Design, synthesis and biological evaluation of new bivalent quinazoline analogues as IAP antagonists
Bae, Inhwan, Kim, Daejin, Choi, Jaeyul, Kim, Jisook, Kim, Minjeong, Park, Bokyung, Kim, Young Hoon, Ahn, Young Gil, Hyung Kim, Ha, Kim, Dae Kyong
Published in Bioorganic & medicinal chemistry letters (15.02.2021)
Published in Bioorganic & medicinal chemistry letters (15.02.2021)
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Abstract 1135: Antitumor activity of novel reversible LSD1 inhibitors in preclinical models of AML and SCLC
Byun, Joo-Yun, Lee, Won Jong, Kim, Won jung, Kim, Minjeong, Bae, Inhwan, Hong, Seokhyun, Kim, Yu-Yon, Park, Hyunjin, Kim, Eunyoung, Kim, Young Hoon, Ahn, Young Gil, Suh, Kwee Hyun
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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A new synthesis of aziridine-2-carboxylates: Reaction of hexahydro-1,3,5-triazines or N-methoxymethylanilines with alkyl diazoacetates in the presence of lewis acid
Ha, Hyun-Joon, Suh, Jang-Min, Kang, Kyung-Ho, Ahn, Young-Gil, Han, Oksoo
Published in Tetrahedron (29.01.1998)
Published in Tetrahedron (29.01.1998)
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Practical synthesis of Taxol side chain
Ha, Hyun-Joon, Park, Gha-Seung, Ahn, Young-Gil, Lee, Gwan Sun
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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