The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
Murphy, James M., Czabotar, Peter E., Hildebrand, Joanne M., Lucet, Isabelle S., Zhang, Jian-Guo, Alvarez-Diaz, Silvia, Lewis, Rowena, Lalaoui, Najoua, Metcalf, Donald, Webb, Andrew I., Young, Samuel N., Varghese, Leila N., Tannahill, Gillian M., Hatchell, Esme C., Majewski, Ian J., Okamoto, Toru, Dobson, Renwick C.J., Hilton, Douglas J., Babon, Jeffrey J., Nicola, Nicos A., Strasser, Andreas, Silke, John, Alexander, Warren S.
Published in Immunity (Cambridge, Mass.) (19.09.2013)
Published in Immunity (Cambridge, Mass.) (19.09.2013)
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Journal Article
Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity
Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.
Published in Immunity (Cambridge, Mass.) (24.02.2012)
Published in Immunity (Cambridge, Mass.) (24.02.2012)
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Journal Article
Presynaptic voltage-gated calcium channels in the auditory brainstem
Young, Samuel M., Veeraraghavan, Priyadharishini
Published in Molecular and cellular neuroscience (01.04.2021)
Published in Molecular and cellular neuroscience (01.04.2021)
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Journal Article
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
Samson, Andre L., Zhang, Ying, Geoghegan, Niall D., Gavin, Xavier J., Davies, Katherine A., Mlodzianoski, Michael J., Whitehead, Lachlan W., Frank, Daniel, Garnish, Sarah E., Fitzgibbon, Cheree, Hempel, Anne, Young, Samuel N., Jacobsen, Annette V., Cawthorne, Wayne, Petrie, Emma J., Faux, Maree C., Shield-Artin, Kristy, Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Rogers, Kelly L., Lessene, Guillaume, Hawkins, Edwin D., Murphy, James M.
Published in Nature communications (19.06.2020)
Published in Nature communications (19.06.2020)
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Journal Article
Thermodynamic Stability and Anion Ordering of Perovskite Oxynitrides
Young, Samuel D., Chen, Jiadong, Sun, Wenhao, Goldsmith, Bryan R., Pilania, Ghanshyam
Published in Chemistry of materials (08.08.2023)
Published in Chemistry of materials (08.08.2023)
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Journal Article
Presynaptic Mitochondria Volume and Abundance Increase during Development of a High-Fidelity Synapse
Thomas, Connon I, Keine, Christian, Okayama, Satoko, Satterfield, Rachel, Musgrove, Morgan, Guerrero-Given, Debbie, Kamasawa, Naomi, Young, Jr, Samuel M
Published in The Journal of neuroscience (09.10.2019)
Published in The Journal of neuroscience (09.10.2019)
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Journal Article
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
Hildebrand, Joanne M., Tanzer, Maria C., Lucet, Isabelle S., Young, Samuel N., Spall, Sukhdeep K., Sharma, Pooja, Pierotti, Catia, Garnier, Jean-Marc, Dobson, Renwick C.J., Webb, Andrew I., Tripaydonis, Anne, Babon, Jeffrey J., Mulcair, Mark D., Scanlon, Martin J., Alexander, Warren S., Wilks, Andrew F., Czabotar, Peter E., Lessene, Guillaume, Murphy, James M., Silke, John
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.10.2014)
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Journal Article
Ca V 2.1 α 1 Subunit Expression Regulates Presynaptic Ca V 2.1 Abundance and Synaptic Strength at a Central Synapse
Lübbert, Matthias, Goral, R Oliver, Keine, Christian, Thomas, Connon, Guerrero-Given, Debbie, Putzke, Travis, Satterfield, Rachel, Kamasawa, Naomi, Young, Jr, Samuel M
Published in Neuron (Cambridge, Mass.) (16.01.2019)
Published in Neuron (Cambridge, Mass.) (16.01.2019)
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Journal Article
Ca2+ channel to synaptic vesicle distance accounts for the readily releasable pool kinetics at a functionally mature auditory synapse
Chen, Zuxin, Das, Brati, Nakamura, Yukihiro, DiGregorio, David A, Young, Jr, Samuel M
Published in The Journal of neuroscience (04.02.2015)
Published in The Journal of neuroscience (04.02.2015)
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Journal Article
The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse
Chen, Zuxin, Cooper, Benjamin, Kalla, Stefan, Varoqueaux, Frederique, Young, Jr, Samuel M
Published in The Journal of neuroscience (08.05.2013)
Published in The Journal of neuroscience (08.05.2013)
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Journal Article
Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts
Rodriguez, Anthony B., Peske, J. David, Woods, Amber N., Leick, Katie M., Mauldin, Ileana S., Meneveau, Max O., Young, Samuel J., Lindsay, Robin S., Melssen, Marit M., Cyranowski, Salwador, Parriott, Geoffrey, Conaway, Mark R., Fu, Yang-Xin, Slingluff, Craig L., Engelhard, Victor H.
Published in Cell reports (Cambridge) (20.07.2021)
Published in Cell reports (Cambridge) (20.07.2021)
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Journal Article
Synaptotagmin 2 Is the Fast Ca2+ Sensor at a Central Inhibitory Synapse
Chen, Chong, Arai, Itaru, Satterfield, Rachel, Young, Samuel M., Jonas, Peter
Published in Cell reports (Cambridge) (17.01.2017)
Published in Cell reports (Cambridge) (17.01.2017)
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