Super-Enhancers in the Control of Cell Identity and Disease
Hnisz, Denes, Abraham, Brian J., Lee, Tong Ihn, Lau, Ashley, Saint-André, Violaine, Sigova, Alla A., Hoke, Heather A., Young, Richard A.
Published in Cell (07.11.2013)
Published in Cell (07.11.2013)
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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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A Phase Separation Model for Transcriptional Control
Hnisz, Denes, Shrinivas, Krishna, Young, Richard A., Chakraborty, Arup K., Sharp, Phillip A.
Published in Cell (23.03.2017)
Published in Cell (23.03.2017)
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Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Lovén, Jakob, Hoke, Heather A., Lin, Charles Y., Lau, Ashley, Orlando, David A., Vakoc, Christopher R., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Lin, Charles Y., Lovén, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published in Cell (28.09.2012)
Published in Cell (28.09.2012)
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Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers
Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Weintraub, Abraham S., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Published in Molecular cell (16.04.2015)
Published in Molecular cell (16.04.2015)
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Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
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Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
Chaffer, Christine L., Marjanovic, Nemanja D., Lee, Tony, Bell, George, Kleer, Celina G., Reinhardt, Ferenc, D’Alessio, Ana C., Young, Richard A., Weinberg, Robert A.
Published in Cell (03.07.2013)
Published in Cell (03.07.2013)
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3D Chromosome Regulatory Landscape of Human Pluripotent Cells
Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Published in Cell stem cell (04.02.2016)
Published in Cell stem cell (04.02.2016)
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Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency
Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Published in Cell stem cell (02.10.2014)
Published in Cell stem cell (02.10.2014)
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Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
Chapuy, Bjoern, McKeown, Michael R., Lin, Charles Y., Monti, Stefano, Roemer, Margaretha G.M., Qi, Jun, Rahl, Peter B., Sun, Heather H., Yeda, Kelly T., Doench, John G., Reichert, Elaine, Kung, Andrew L., Rodig, Scott J., Young, Richard A., Shipp, Margaret A., Bradner, James E.
Published in Cancer cell (09.12.2013)
Published in Cancer cell (09.12.2013)
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Journal Article
RNA in formation and regulation of transcriptional condensates
Sharp, Phillip A, Chakraborty, Arup K, Henninger, Jonathan E, Young, Richard A
Published in RNA (Cambridge) (01.01.2022)
Published in RNA (Cambridge) (01.01.2022)
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Journal Article
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
Guo, Yang Eric, Manteiga, John C., Henninger, Jonathan E., Sabari, Benjamin R., Dall’Agnese, Alessandra, Hannett, Nancy M., Spille, Jan-Hendrik, Afeyan, Lena K., Zamudio, Alicia V., Shrinivas, Krishna, Abraham, Brian J., Boija, Ann, Decker, Tim-Michael, Rimel, Jenna K., Fant, Charli B., Lee, Tong Ihn, Cisse, Ibrahim I., Sharp, Phillip A., Taatjes, Dylan J., Young, Richard A.
Published in Nature (London) (01.08.2019)
Published in Nature (London) (01.08.2019)
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Journal Article
Revisiting Global Gene Expression Analysis
Lovén, Jakob, Orlando, David A., Sigova, Alla A., Lin, Charles Y., Rahl, Peter B., Burge, Christopher B., Levens, David L., Lee, Tong Ihn, Young, Richard A.
Published in Cell (26.10.2012)
Published in Cell (26.10.2012)
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Journal Article
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Weintraub, Abraham S., Li, Charles H., Zamudio, Alicia V., Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Jaenisch, Rudolf, Bradner, James E., Gray, Nathanael S., Young, Richard A.
Published in Cell (14.12.2017)
Published in Cell (14.12.2017)
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Journal Article
Coactivator condensation at super-enhancers links phase separation and gene control
Sabari, Benjamin R, Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A, Coffey, Eliot L, Shrinivas, Krishna, Abraham, Brian J, Hannett, Nancy M, Zamudio, Alicia V, Manteiga, John C, Li, Charles H, Guo, Yang E, Day, Daniel S, Schuijers, Jurian, Vasile, Eliza, Malik, Sohail, Hnisz, Denes, Lee, Tong Ihn, Cisse, Ibrahim I, Roeder, Robert G, Sharp, Phillip A, Chakraborty, Arup K, Young, Richard A
Published in Science (American Association for the Advancement of Science) (27.07.2018)
Published in Science (American Association for the Advancement of Science) (27.07.2018)
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Journal Article
Transcription factor trapping by RNA in gene regulatory elements
Sigova, Alla A., Abraham, Brian J., Ji, Xiong, Molinie, Benoit, Hannett, Nancy M., Guo, Yang Eric, Jangi, Mohini, Giallourakis, Cosmas C., Sharp, Phillip A., Young, Richard A.
Published in Science (American Association for the Advancement of Science) (20.11.2015)
Published in Science (American Association for the Advancement of Science) (20.11.2015)
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