Studies of Phosphoproteomic Changes Induced by Nucleophosmin-Anaplastic Lymphoma Kinase (ALK) Highlight Deregulation of Tumor Necrosis Factor (TNF)/Fas/TNF-related Apoptosis-induced Ligand Signaling Pathway in ALK-positive Anaplastic Large Cell Lymphoma
Wu, Fang, Wang, Peng, Zhang, Jingdong, Young, Leah C., Lai, Raymond, Li, Liang
Published in Molecular & cellular proteomics (01.07.2010)
Published in Molecular & cellular proteomics (01.07.2010)
Get full text
Journal Article
Functional Characterization of the Kinase Activation Loop in Nucleophosmin (NPM)-Anaplastic Lymphoma Kinase (ALK) Using Tandem Affinity Purification and Liquid Chromatography-Mass Spectrometry
Wang, Peng, Wu, Fang, Ma, Yupo, Li, Liang, Lai, Raymond, Young, Leah C.
Published in The Journal of biological chemistry (01.01.2010)
Published in The Journal of biological chemistry (01.01.2010)
Get full text
Journal Article
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
Mallette, Frédérick A, Mattiroli, Francesca, Cui, Gaofeng, Young, Leah C, Hendzel, Michael J, Mer, Georges, Sixma, Titia K, Richard, Stéphane
Published in The EMBO journal (18.04.2012)
Published in The EMBO journal (18.04.2012)
Get full text
Journal Article
Polycomb repressive complex 2 contributes to DNA double-strand break repair
Campbell, Stuart, Ismail, Ismail Hassan, Young, Leah C, Poirier, Guy G, Hendzel, Michael J
Published in Cell cycle (Georgetown, Tex.) (15.08.2013)
Published in Cell cycle (Georgetown, Tex.) (15.08.2013)
Get full text
Journal Article
Defining the DNA mismatch repair-dependent apoptotic pathway in primary cells: Evidence for p53-independence and involvement of centrosomal caspase 2
Narine, Kelly A.D., Keuling, Angela M., Gombos, Randi, Tron, Victor A., Andrew, Susan E., Young, Leah C.
Published in DNA repair (04.02.2010)
Published in DNA repair (04.02.2010)
Get full text
Journal Article
Ensuring access to innovative therapies for children, adolescents, and young adults across Canada: The single patient study experience
Revon-Riviere, Gabriel, Young, Leah C, Stephenson, Elizabeth A, Brodeur-Robb, Kathy, Cohen-Gogo, Sarah, Deyell, Rebecca, Lacaze-Masmonteil, Thierry, Palmer, Antonia, Parekh, Rulan S, Whitlock, James A, Morgenstern, Daniel A
Published in Paediatrics & child health (01.11.2023)
Published in Paediatrics & child health (01.11.2023)
Get more information
Journal Article
Proteome-Wide Identification of Novel Binding Partners to the Oncogenic Fusion Gene Protein, NPM-ALK, using Tandem Affinity Purification and Mass Spectrometry
Wu, Fang, Wang, Peng, Young, Leah C, Lai, Raymond, Li, Liang
Published in The American journal of pathology (01.02.2009)
Published in The American journal of pathology (01.02.2009)
Get full text
Journal Article
Changes in biomarkers of bone turnover in an aripiprazole add-on or switching study
Lodhi, Rohit J, Masand, Salaj, Malik, Amna, Shivakumar, Kuppuswami, McAllister, Victoria D.M, O'Keane, Veronica, Young, Leah C, Heald, Adrian H, Sherwood, Roy A, Aitchison, Katherine J
Published in Schizophrenia research (01.02.2016)
Published in Schizophrenia research (01.02.2016)
Get full text
Journal Article
IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells
Shi, Ping, Lai, Raymond, Lin, Quan, Iqbal, Abid S., Young, Leah C., Kwak, Larry W., Ford, Richard J., Amin, Hesham M.
Published in Blood (09.07.2009)
Published in Blood (09.07.2009)
Get full text
Journal Article
Fusion Tyrosine Kinase NPM-ALK Deregulates MSH2 and Suppresses DNA Mismatch Repair Function Novel Insights into a Potent Oncoprotein
YOUNG, Leah C, BONE, Kathleen M, LAI, Raymond, PENG WANG, FANG WU, ADAM, Benjamin A, HEGAZY, Samar, GELEBART, Pascal, HOLOVATI, Jelena, LIANG LI, ANDREW, Susan E
Published in The American journal of pathology (01.07.2011)
Published in The American journal of pathology (01.07.2011)
Get full text
Journal Article
Serine phosphorylation of NPM―ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential
PENG WANG, FANG WU, JINGDONG ZHANG, MCMULLEN, Todd, YOUNG, Leah C, INGHAM, Robert J, LIANG LI, LAI, Raymond
Published in Carcinogenesis (New York) (01.02.2011)
Published in Carcinogenesis (New York) (01.02.2011)
Get full text
Journal Article
Fusion Tyrosine Kinase NPM-ALK Deregulates MSH2 and Suppresses DNA Mismatch Repair Function
Young, Leah C, Bone, Kathleen M, Wang, Peng, Wu, Fang, Adam, Benjamin A, Hegazy, Samar, Gelebart, Pascal, Holovati, Jelena, Li, Liang, Andrew, Susan E, Lai, Raymond
Published in The American journal of pathology (2011)
Published in The American journal of pathology (2011)
Get full text
Journal Article
DNA Mismatch Repair Protein Msh6 Is Required for Optimal Levels of Ultraviolet-B-Induced Apoptosis in Primary Mouse Fibroblasts
Young, Leah C., Peters, Anthea C., Maeda, Tomoko, Edelmann, Winfried, Kucherlapati, Raju, Andrew, Susan E., Tron, Victor A.
Published in Journal of investigative dermatology (01.10.2003)
Published in Journal of investigative dermatology (01.10.2003)
Get full text
Journal Article