A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice
Escribano-Díaz, Cristina, Orthwein, Alexandre, Fradet-Turcotte, Amélie, Xing, Mengtan, Young, Jordan T.F., Tkáč, Ján, Cook, Michael A., Rosebrock, Adam P., Munro, Meagan, Canny, Marella D., Xu, Dongyi, Durocher, Daniel
Published in Molecular cell (07.03.2013)
Published in Molecular cell (07.03.2013)
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Journal Article
HELB Is a Feedback Inhibitor of DNA End Resection
Tkáč, Ján, Xu, Guotai, Adhikary, Hemanta, Young, Jordan T.F., Gallo, David, Escribano-Díaz, Cristina, Krietsch, Jana, Orthwein, Alexandre, Munro, Meagan, Sol, Wendy, Al-Hakim, Abdallah, Lin, Zhen-Yuan, Jonkers, Jos, Borst, Piet, Brown, Grant W., Gingras, Anne-Claude, Rottenberg, Sven, Masson, Jean-Yves, Durocher, Daniel
Published in Molecular cell (04.02.2016)
Published in Molecular cell (04.02.2016)
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The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination
O'Donnell, Lara, Panier, Stephanie, Wildenhain, Jan, Tkach, Johnny M., Al-Hakim, Abdallah, Landry, Marie-Claude, Escribano-Diaz, Cristina, Szilard, Rachel K., Young, Jordan T.F., Munro, Meagan, Canny, Marella D., Kolas, Nadine K., Zhang, Wei, Harding, Shane M., Ylanko, Jarkko, Mendez, Megan, Mullin, Michael, Sun, Thomas, Habermann, Bianca, Datti, Alessandro, Bristow, Robert G., Gingras, Anne-Claude, Tyers, Michael D., Brown, Grant W., Durocher, Daniel
Published in Molecular cell (24.11.2010)
Published in Molecular cell (24.11.2010)
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Journal Article
Profound synthetic lethality between SMARCAL1 and FANCM
Feng, Sumin, Liu, Kaiwen, Shang, Jinfeng, Hoeg, Lisa, Pastore, Graziana, Yang, William, Roy, Sabrina, Sastre-Moreno, Guillermo, Young, Jordan T.F., Wu, Wei, Xu, Dongyi, Durocher, Daniel
Published in Molecular cell (01.11.2024)
Published in Molecular cell (01.11.2024)
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Journal Article
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel
Published in Nature (London) (28.04.2022)
Published in Nature (London) (28.04.2022)
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Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T F, Roulston, Anne, Zinda, Michael
Published in Cell reports (Cambridge) (12.07.2022)
Published in Cell reports (Cambridge) (12.07.2022)
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Guiding ATR and PARP inhibitor combinations with chemogenomic screens
Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T.F., Roulston, Anne, Zinda, Michael
Published in Cell reports (Cambridge) (12.07.2022)
Published in Cell reports (Cambridge) (12.07.2022)
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RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors
Roulston, Anne, Zimmermann, Michal, Papp, Robert, Skeldon, Alexander, Pellerin, Charles, Dumas-Bérube, Émilie, Dumais, Valerie, Dorich, Stéphane, Fader, Lee D, Fournier, Sara, Li, Li, Leclaire, Marie-Eve, Yin, Shou Yun, Chefson, Amandine, Alam, Hunain, Yang, William, Fugère-Desjardins, Chloe, Vignini-Hammond, Sabrina, Skorey, Kathryn, Mulani, Amina, Rimkunas, Victoria, Veloso, Artur, Hamel, Martine, Stocco, Rino, Mamane, Yael, Li, Zuomei, Young, Jordan T F, Zinda, Michael, Black, W Cameron
Published in Molecular cancer therapeutics (01.02.2022)
Published in Molecular cancer therapeutics (01.02.2022)
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The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer
Adam, Salomé, Rossi, Silvia Emma, Moatti, Nathalie, De Marco Zompit, Mara, Xue, Yibo, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Yin, Shou Yun, Papp, Robert, Young, Jordan T F, Zinda, Michael, Stucki, Manuel, Durocher, Daniel
Published in Nature cancer (01.12.2021)
Published in Nature cancer (01.12.2021)
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Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease
Álvarez-Quilón, Alejandro, Wojtaszek, Jessica L., Mathieu, Marie-Claude, Patel, Tejas, Appel, C. Denise, Hustedt, Nicole, Rossi, Silvia Emma, Wallace, Bret D., Setiaputra, Dheva, Adam, Salomé, Ohashi, Yota, Melo, Henrique, Cho, Tiffany, Gervais, Christian, Muñoz, Ivan M., Grazzini, Eric, Young, Jordan T.F., Rouse, John, Zinda, Michael, Williams, R. Scott, Durocher, Daniel
Published in Molecular cell (18.06.2020)
Published in Molecular cell (18.06.2020)
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Journal Article
LSD1 is required for euchromatic origin firing and replication timing
Wang, Yue, Huang, Yunchao, Cheng, Edith, Liu, Xinhua, Zhang, Yu, Yang, Jianguo, Young, Jordan T. F., Brown, Grant W., Yang, Xiaohan, Shang, Yongfeng
Published in Signal transduction and targeted therapy (13.04.2022)
Published in Signal transduction and targeted therapy (13.04.2022)
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Simultaneous exposure of Xenopus A6 kidney epithelial cells to concurrent mild sodium arsenite and heat stress results in enhanced hsp30 and hsp70 gene expression and the acquisition of thermotolerance
Young, Jordan T.F., Gauley, Julie, Heikkila, John J.
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01.08.2009)
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01.08.2009)
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