Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma
McDonald, Michelle M., Reagan, Michaela R., Youlten, Scott E., Mohanty, Sindhu T., Seckinger, Anja, Terry, Rachael L., Pettitt, Jessica A., Simic, Marija K., Cheng, Tegan L., Morse, Alyson, Le, Lawrence M.T., Abi-Hanna, David, Kramer, Ina, Falank, Carolyne, Fairfield, Heather, Ghobrial, Irene M., Baldock, Paul A., Little, David G., Kneissel, Michaela, Vanderkerken, Karin, Bassett, J.H.Duncan, Williams, Graham R., Oyajobi, Babatunde O., Hose, Dirk, Phan, Tri G., Croucher, Peter I.
Published in Blood (29.06.2017)
Published in Blood (29.06.2017)
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Accelerating functional gene discovery in osteoarthritis
Butterfield, Natalie C., Curry, Katherine F., Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S., Adoum, Anne-Tounsia, Leitch, Victoria D., Logan, John G., Waung, Julian A., Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E., Wilkinson, J. Mark, McAninch, Elizabeth A., Vancollie, Valerie E., Kussy, Fiona, White, Jacqueline K., Lelliott, Christopher J., Adams, David J., Jacques, Richard, Bianco, Antonio C., Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan
Published in Nature communications (20.01.2021)
Published in Nature communications (20.01.2021)
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A universal molecular control for DNA, mRNA and protein expression
Gunter, Helen M., Youlten, Scott E., Reis, Andre L. M., McCubbin, Tim, Madala, Bindu Swapna, Wong, Ted, Stevanovski, Igor, Cipponi, Arcadi, Deveson, Ira W., Santini, Nadia S., Kummerfeld, Sarah, Croucher, Peter I., Marcellin, Esteban, Mercer, Tim R.
Published in Nature communications (20.03.2024)
Published in Nature communications (20.03.2024)
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Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease
Bergen, Dylan J M, Tong, Qiao, Shukla, Ankit, Newham, Elis, Zethof, Jan, Lundberg, Mischa, Ryan, Rebecca, Youlten, Scott E, Frysz, Monika, Croucher, Peter I, Flik, Gert, Richardson, Rebecca J, Kemp, John P, Hammond, Chrissy L, Metz, Juriaan R
Published in BMC biology (21.01.2022)
Published in BMC biology (21.01.2022)
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Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes
Gregson, Celia L., Newell, Felicity, Leo, Paul J., Clark, Graeme R., Paternoster, Lavinia, Marshall, Mhairi, Forgetta, Vincenzo, Morris, John A., Ge, Bing, Bao, Xiao, Duncan Bassett, J.H., Williams, Graham R., Youlten, Scott E., Croucher, Peter I., Davey Smith, George, Evans, David M., Kemp, John P., Brown, Matthew A., Tobias, Jon H., Duncan, Emma L.
Published in Bone (New York, N.Y.) (01.09.2018)
Published in Bone (New York, N.Y.) (01.09.2018)
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Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing
Gunter, Helen M., Youlten, Scott E., Madala, Bindu Swapna, Reis, Andre L. M., Stevanovski, Igor, Wong, Ted, Kummerfield, Sarah K., Deveson, Ira W., Santini, Nadia S., Marcellin, Esteban, Mercer, Tim R.
Published in Nature communications (28.10.2022)
Published in Nature communications (28.10.2022)
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Journal Article
Publisher Correction: Accelerating functional gene discovery in osteoarthritis
Butterfield, Natalie C., Curry, Katherine F., Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S., Adoum, Anne-Tounsia, Leitch, Victoria D., Logan, John G., Waung, Julian A., Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E., Wilkinson, J. Mark, McAninch, Elizabeth A., Vancollie, Valerie E., Kussy, Fiona, White, Jacqueline K., Lelliott, Christopher J., Adams, David J., Jacques, Richard, Bianco, Antonio C., Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan
Published in Nature communications (28.05.2021)
Published in Nature communications (28.05.2021)
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An atlas of genetic influences on osteoporosis in humans and mice
Morris, John A., Kemp, John P., Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan C., Vulpescu, Nicholas A., Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu T., Sergio, C. Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee-Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide S. K., Pollard, Andrea S., Dewhurst, Hannah F., Hassall, Thomas A. D., Beltejar, Michael-John G., Adams, Douglas J., Vaillancourt, Suzanne M., Kaptoge, Stephen, Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia E., Evangelou, Evangelos, Ohlsson, Claes, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas P., Tobias, Jonathan H., Gregson, Celia L., Harvey, Nicholas C., Grundberg, Elin, Goltzman, David, Adams, David J., Lelliott, Christopher J., Hinds, David A., Ackert-Bicknell, Cheryl L., Hsu, Yi-Hsiang, Maurano, Matthew T., Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan, Evans, David M., Richards, J. Brent
Published in Nature genetics (01.02.2019)
Published in Nature genetics (01.02.2019)
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Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, Michelle M., Khoo, Weng Hua, Ng, Pei Ying, Xiao, Ya, Zamerli, Jad, Thatcher, Peter, Kyaw, Wunna, Pathmanandavel, Karrnan, Grootveld, Abigail K., Moran, Imogen, Butt, Danyal, Nguyen, Akira, Corr, Alexander, Warren, Sean, Biro, Maté, Butterfield, Natalie C., Guilfoyle, Siobhan E., Komla-Ebri, Davide, Dack, Michael R.G., Dewhurst, Hannah F., Logan, John G., Li, Yongxiao, Mohanty, Sindhu T., Byrne, Niall, Terry, Rachael L., Simic, Marija K., Chai, Ryan, Quinn, Julian M.W., Youlten, Scott E., Pettitt, Jessica A., Abi-Hanna, David, Jain, Rohit, Weninger, Wolfgang, Lundberg, Mischa, Sun, Shuting, Ebetino, Frank H., Timpson, Paul, Lee, Woei Ming, Baldock, Paul A., Rogers, Michael J., Brink, Robert, Williams, Graham R., Bassett, J.H. Duncan, Kemp, John P., Pavlos, Nathan J., Croucher, Peter I., Phan, Tri Giang
Published in Cell (04.03.2021)
Published in Cell (04.03.2021)
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Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
Kemp, John P, Morris, John A, Medina-Gomez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M, Youlten, Scott E, Zheng, Jie, Gregson, Celia L, Grundberg, Elin, Trajanoska, Katerina, Logan, John G, Pollard, Andrea S, Sparkes, Penny C, Ghirardello, Elena J, Allen, Rebecca, Leitch, Victoria D, Butterfield, Natalie C, Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F, White, Jacqueline K, Kussy, Fiona, Greenlaw, Keelin M, Xu, Changjiang, Harvey, Nicholas C, Cooper, Cyrus, Adams, David J, Greenwood, Celia M T, Maurano, Matthew T, Kaptoge, Stephen, Rivadeneira, Fernando, Tobias, Jonathan H, Croucher, Peter I, Ackert-Bicknell, Cheryl L, Bassett, J H Duncan, Williams, Graham R, Richards, J Brent, Evans, David M
Published in Nature genetics (01.10.2017)
Published in Nature genetics (01.10.2017)
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Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy
Yam, Andrew O, Bailey, Jacqueline, Lin, Francis, Jakovija, Arnolda, Youlten, Scott E, Counoupas, Claudio, Gunzer, Matthias, Bald, Tobias, Woodruff, Trent M, Triccas, James A, Goldstein, Leonard D, Gallego-Ortega, David, Grey, Shane T, Chtanova, Tatyana
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Youlten, Scott E., Kemp, John P., Logan, John G., Ghirardello, Elena J., Sergio, Claudio M., Dack, Michael R. G., Guilfoyle, Siobhan E., Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Chai, Ryan C., Corr, Alexander P., Smith, James T., Mohanty, Sindhu T., Morris, John A., McDonald, Michelle M., Quinn, Julian M. W., McGlade, Amelia R., Bartonicek, Nenad, Jansson, Matt, Hatzikotoulas, Konstantinos, Irving, Melita D., Beleza-Meireles, Ana, Rivadeneira, Fernando, Duncan, Emma, Richards, J. Brent, Adams, David J., Lelliott, Christopher J., Brink, Robert, Phan, Tri Giang, Eisman, John A., Evans, David M., Zeggini, Eleftheria, Baldock, Paul A., Bassett, J. H. Duncan, Williams, Graham R., Croucher, Peter I.
Published in Nature communications (05.05.2021)
Published in Nature communications (05.05.2021)
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Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue
Venkat, Aarthi, Carlino, Maximillian J, Lawton, Betty R, Prasad, Manju L, Amodio, Matthew, Gibson, Courtney E, Zeiss, Caroline J, Youlten, Scott E, Krishnaswamy, Smita, Krause, Diane S
Published in Genome research (01.06.2024)
Published in Genome research (01.06.2024)
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Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
McDonald, Michelle M., Khoo, Weng Hua, Ng, Pei Ying, Xiao, Ya, Zamerli, Jad, Thatcher, Peter, Kyaw, Wunna, Pathmanandavel, Karrnan, Grootveld, Abigail K., Moran, Imogen, Butt, Danyal, Nguyen, Akira, Corr, Alexander, Warren, Sean, Biro, Maté, Butterfield, Natalie C., Guilfoyle, Siobhan E., Komla-Ebri, Davide, Dack, Michael R.G., Dewhurst, Hannah F., Logan, John G., Li, Yongxiao, Mohanty, Sindhu T., Byrne, Niall, Terry, Rachael L., Simic, Marija K., Chai, Ryan, Quinn, Julian M.W., Youlten, Scott E., Pettitt, Jessica A., Abi-Hanna, David, Jain, Rohit, Weninger, Wolfgang, Lundberg, Mischa, Sun, Shuting, Ebetino, Frank H., Timpson, Paul, Lee, Woei Ming, Baldock, Paul A., Rogers, Michael J., Brink, Robert, Williams, Graham R., Bassett, J.H. Duncan, Kemp, John P., Pavlos, Nathan J., Croucher, Peter I., Phan, Tri Giang
Published in Cell (01.04.2021)
Published in Cell (01.04.2021)
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Single-cell multi-modal GAN reveals spatial patterns in single-cell data from triple-negative breast cancer
Amodio, Matthew, Youlten, Scott E., Venkat, Aarthi, San Juan, Beatriz P., Chaffer, Christine L., Krishnaswamy, Smita
Published in Patterns (New York, N.Y.) (09.09.2022)
Published in Patterns (New York, N.Y.) (09.09.2022)
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Author Correction: An atlas of genetic influences on osteoporosis in humans and mice
Morris, John A., Kemp, John P., Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan C., Vulpescu, Nicholas A., Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu T., Sergio, C. Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee-Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide S. K., Pollard, Andrea S., Dewhurst, Hannah F., Hassall, Thomas A. D., Beltejar, Michael-John G., Adams, Douglas J., Vaillancourt, Suzanne M., Kaptoge, Stephen, Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia E., Evangelou, Evangelos, Ohlsson, Claes, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas P., Tobias, Jonathan H., Gregson, Celia L., Harvey, Nicholas C., Grundberg, Elin, Goltzman, David, Adams, David J., Lelliott, Christopher J., Hinds, David A., Ackert-Bicknell, Cheryl L., Hsu, Yi-Hsiang, Maurano, Matthew T., Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan, Evans, David M., Richards, J. Brent
Published in Nature genetics (01.05.2019)
Published in Nature genetics (01.05.2019)
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Novel cell states arise in embryonic cells devoid of key reprogramming factors
Youlten, Scott E, Miao, Liyun, Hoppe, Caroline, Boswell, Curtis W, Musaev, Damir, Abdelmessih, Mario, Krishnaswamy, Smita, Tornini, Valerie A, Giraldez, Antonio J
Published in bioRxiv (15.05.2024)
Published in bioRxiv (15.05.2024)
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Journal Article
The transcriptome of regenerating zebrafish scales identifies genes involved in human bone disease
Bergen, Dylan Jm, Qiao Tong, Shukla, Ankit, Newman, Elis, Zethof, Jan, Lundberg, Mischa, Ryan, Rebecca, Youlten, Scott E, Zeggini, Eleftheria, Croucher, Peter I, Flik, Gert, Richardson, Rebecca J, Kemp, John P, Hammond, Chrissy L, Metz, Juriaan R
Published in bioRxiv (09.10.2020)
Published in bioRxiv (09.10.2020)
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