Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate‑1 Receptor
Buzard, Daniel J, Kim, Sun Hee, Lopez, Luis, Kawasaki, Andrew, Zhu, Xiuwen, Moody, Jeanne, Thoresen, Lars, Calderon, Imelda, Ullman, Brett, Han, Sangdon, Lehmann, Juerg, Gharbaoui, Tawfik, Sengupta, Dipanjan, Calvano, Lorene, Montalban, Antonio Garrido, Ma, You-An, Sage, Carleton, Gao, Yinghong, Semple, Graeme, Edwards, Jeff, Barden, Jeremy, Morgan, Michael, Chen, Weichao, Usmani, Khawja, Chen, Chuan, Sadeque, Abu, Christopher, Ronald J, Thatte, Jayant, Fu, Lixia, Solomon, Michelle, Mills, David, Whelan, Kevin, Al-Shamma, Hussien, Gatlin, Joel, Le, Minh, Gaidarov, Ibragim, Anthony, Todd, Unett, David J, Blackburn, Anthony, Rueter, Jaimie, Stirn, Scott, Behan, Dominic P, Jones, Robert M
Published in ACS medicinal chemistry letters (11.12.2014)
Published in ACS medicinal chemistry letters (11.12.2014)
Get full text
Journal Article
An Efficient Scale-Up Process for the Preparation of the APD334 Precursor 4‑Chloromethyl-1-cyclopentyl-2-(trifluoromethyl)benzene
Sengupta, Dipanjan, Gharbaoui, Tawfik, Krishnan, Ashwin, Buzard, Daniel J, Jones, Robert M, Ma, You-An, Burda, Robert, Garrido Montalban, Antonio, Semple, Graeme
Published in Organic process research & development (19.06.2015)
Published in Organic process research & development (19.06.2015)
Get full text
Journal Article
Design and Synthesis of Human Immunodeficiency Virus Entry Inhibitors: Sulfonamide as an Isostere for the α-Ketoamide Group
Lu, Rong-Jian, Tucker, John A, Zinevitch, Tatiana, Kirichenko, Olga, Konoplev, Vitalii, Kuznetsova, Svetlana, Sviridov, Sergey, Pickens, Jason, Tandel, Sagun, Brahmachary, Enugurthi, Yang, Yang, Wang, Jian, Freel, Stephanie, Fisher, Shelly, Sullivan, Alana, Zhou, Jiying, Stanfield-Oakley, Sherry, Greenberg, Michael, Bolognesi, Dani, Bray, Brian, Koszalka, Barney, Jeffs, Peter, Khasanov, Alisher, Ma, You-An, Jeffries, Cynthia, Liu, Changhui, Proskurina, Tatiana, Zhu, Tong, Chucholowski, Alexander, Li, Rongshi, Sexton, Connie
Published in Journal of medicinal chemistry (27.12.2007)
Published in Journal of medicinal chemistry (27.12.2007)
Get full text
Journal Article
Heterobiaryl Human Immunodeficiency Virus Entry Inhibitors
Lu, Rong-Jian, Tucker, John A, Pickens, Jason, Ma, You-An, Zinevitch, Tatiana, Kirichenko, Olga, Konoplev, Vitalii, Kuznetsova, Svetlana, Sviridov, Sergey, Brahmachary, Enugurthi, Khasanov, Alisher, Mikel, Charles, Yang, Yang, Liu, Changhui, Wang, Jian, Freel, Stephanie, Fisher, Shelly, Sullivan, Alana, Zhou, Jiying, Stanfield-Oakley, Sherry, Baker, Brian, Sailstad, Jeff, Greenberg, Michael, Bolognesi, Dani, Bray, Brian, Koszalka, Barney, Jeffs, Peter, Jeffries, Cynthia, Chucholowski, Alexander, Sexton, Connie
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
Get full text
Journal Article
One-pot syntheses of 6-mercaptopurines (6MP) from 4,5-diamino-6-chloro-pyrimidines
Tandel, Sagun, Bliznets, Igor, Ebinger, Katalin, Ma, You-An, Bhumralkar, Dilip, Thiruvazhi, Mohan
Published in Tetrahedron letters (08.03.2004)
Published in Tetrahedron letters (08.03.2004)
Get full text
Journal Article
Enzymatic Mechanism of Thyroxine Biosynthesis. Identification of the “Lost Three-Carbon Fragment”
Ma, You-An, Sih, Charles J, Harms, Amy
Published in Journal of the American Chemical Society (29.09.1999)
Published in Journal of the American Chemical Society (29.09.1999)
Get full text
Journal Article
SELECTIVE MONOPHENYLATION OF AN ACTIVE METHYLENE COMPOUND
ODONNELL, MJ, BENNETT, WD, JACOBSEN, WN, MA, YA, HUFFMAN, JC
Published in Tetrahedron letters (01.01.1989)
Published in Tetrahedron letters (01.01.1989)
Get more information
Journal Article
Enzymatic oxidative coupling of hydroxyphenylglycine derivatives
Guo, Zhi-Wei, Machiya, Koji, Ma, You-An, Sih, Charles J.
Published in Tetrahedron letters (06.08.1998)
Published in Tetrahedron letters (06.08.1998)
Get full text
Journal Article
MOLYBDENUM-CATALYZED ALLYLIC AMINATION
SRIVASTAVA, A, MA, YA, PANKAYATSELVAN, R, DINGES, W, NICHOLAS, KM
Published in Journal of the Chemical Society. Chemical communications (1992)
Published in Journal of the Chemical Society. Chemical communications (1992)
Get full text
Journal Article
One-Pot Syntheses of 6-Mercaptopurines (6MP) from 4,5-Diamino-6-chloro-pyrimidines
Tandel, Sagun, Bliznets, Igor, Ebinger, Katalin, Ma, You-An, Bhumralkar, Dilip, Thiruvazhi, Mohan
Published in ChemInform (22.06.2004)
Published in ChemInform (22.06.2004)
Get full text
Journal Article
Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders
Blackburn, Anthony C, Shakya, Sagar Raj, Carlos, Marlon, Hadd, Mark A, Castro, Ryan O, Ma, You-An, Rueter, Jaimie Karyn, Selvey, Lee Alani, Montalban, Antonio Garrido
Year of Publication 25.07.2024
Get full text
Year of Publication 25.07.2024
Patent
CRYSTALLINE L-ARGININE SALT OF (R)-2-(7-(4-CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)-1,2,3, 4-TETRAHYDROCYCLO-PENTA [B]INDOL-3-YL)ACETIC ACID(COMPOUND1) FOR USE IN SIPI RECEPTOR-ASSOCIATED DISORDERS
Blackburn, Anthony C, Hadd, Mark Allen, Shakya, Sagar Raj, Carlos, Marlon, Castro, Ryan O, Ma, You-An, Rueter, Jaimie Karyn, Selvey, Lee Alani, Montalban, Antonio Garrido
Year of Publication 02.05.2024
Get full text
Year of Publication 02.05.2024
Patent
Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders
Blackburn, Anthony C, Hadd, Mark Allen, Shakya, Sagar Raj, Carlos, Marlon, Castro, Ryan O, Ma, You-An, Rueter, Jaimie Karyn, Selvey, Lee Alani, Montalban, Antonio Garrido
Year of Publication 30.01.2024
Get full text
Year of Publication 30.01.2024
Patent
Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
Blackburn, Anthony C, Shakya, Sagar Raj, Carlos, Marlon, Hadd, Mark A, Castro, Ryan O, Ma, You-An, Rueter, Jaimie Karyn, Selvey, Lee Alani, Montalban, Antonio Garrido
Year of Publication 22.12.2023
Get full text
Year of Publication 22.12.2023
Patent
Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in S1P1 receptor-associated disorders
Blackburn, Anthony C, Shakya, Sagar Raj, Carlos, Marlon, Hadd, Mark A, Castro, Ryan O, Ma, You-An, Rueter, Jaimie Karyn, Selvey, Lee Alani, Montalban, Antonio Garrido
Year of Publication 23.03.2023
Get full text
Year of Publication 23.03.2023
Patent