Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis
Liu, Xiaoguang, Nie, Litong, Zhang, Yilei, Yan, Yuelong, Wang, Chao, Colic, Medina, Olszewski, Kellen, Horbath, Amber, Chen, Xiong, Lei, Guang, Mao, Chao, Wu, Shiqi, Zhuang, Li, Poyurovsky, Masha V., James You, M., Hart, Traver, Billadeau, Daniel D., Chen, Junjie, Gan, Boyi
Published in Nature cell biology (01.03.2023)
Published in Nature cell biology (01.03.2023)
Get full text
Journal Article
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
Liu, Xiaoguang, Olszewski, Kellen, Zhang, Yilei, Lim, Esther W., Shi, Jiejun, Zhang, Xiaoshan, Zhang, Jie, Lee, Hyemin, Koppula, Pranavi, Lei, Guang, Zhuang, Li, You, M. James, Fang, Bingliang, Li, Wei, Metallo, Christian M., Poyurovsky, Masha V., Gan, Boyi
Published in Nature cell biology (01.04.2020)
Published in Nature cell biology (01.04.2020)
Get full text
Journal Article
SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells
Yan, Yuelong, Teng, Hongqi, Hang, Qinglei, Kondiparthi, Lavanya, Lei, Guang, Horbath, Amber, Liu, Xiaoguang, Mao, Chao, Wu, Shiqi, Zhuang, Li, James You, M., Poyurovsky, Masha V., Ma, Li, Olszewski, Kellen, Gan, Boyi
Published in Nature communications (21.06.2023)
Published in Nature communications (21.06.2023)
Get full text
Journal Article
A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
Yao, Fan, Deng, Yalan, Zhao, Yang, Mei, Ying, Zhang, Yilei, Liu, Xiaoguang, Martinez, Consuelo, Su, Xiaohua, Rosato, Roberto R., Teng, Hongqi, Hang, Qinglei, Yap, Shannon, Chen, Dahu, Wang, Yumeng, Chen, Mei-Ju May, Zhang, Mutian, Liang, Han, Xie, Dong, Chen, Xin, Zhu, Hao, Chang, Jenny C., You, M. James, Sun, Yutong, Gan, Boyi, Ma, Li
Published in Nature communications (17.12.2021)
Published in Nature communications (17.12.2021)
Get full text
Journal Article
Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety
Nguyen, Nhung Thi, Huang, Kai, Zeng, Hongxiang, Jing, Ji, Wang, Rui, Fang, Shaohai, Chen, Joyce, Liu, Xin, Huang, Zixian, You, M. James, Rao, Anjana, Huang, Yun, Han, Gang, Zhou, Yubin
Published in Nature nanotechnology (01.12.2021)
Published in Nature nanotechnology (01.12.2021)
Get full text
Journal Article
Hexokinase 2-Mediated Warburg Effect Is Required for PTEN- and p53-Deficiency-Driven Prostate Cancer Growth
Wang, Lei, Xiong, Hua, Wu, Fengxia, Zhang, Yingjie, Wang, Ji, Zhao, Liyan, Guo, Xiaolan, Chang, Li-Ju, Zhang, Yong, You, M. James, Koochekpour, Shahriar, Saleem, Mohammad, Huang, Haojie, Lu, Junxuan, Deng, Yibin
Published in Cell reports (Cambridge) (11.09.2014)
Published in Cell reports (Cambridge) (11.09.2014)
Get full text
Journal Article
The Role of Tumor-Associated Macrophages in Leukemia
Li, Yueyang, You, M James, Yang, Yaling, Hu, Dongzhi, Tian, Chen
Published in Acta haematologica (01.03.2020)
Published in Acta haematologica (01.03.2020)
Get more information
Journal Article
A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis
Rezaeian, Abdol-Hossein, Li, Chien-Feng, Wu, Ching-Yuan, Zhang, Xian, Delacerda, Jorge, You, M. James, Han, Fei, Cai, Zhen, Jeong, Yun Seong, Jin, Guoxiang, Phan, Liem, Chou, Ping-Chieh, Lee, Mong-Hong, Hung, Mien-Chie, Sarbassov, Dos, Lin, Hui-Kuan
Published in Nature cell biology (01.01.2017)
Published in Nature cell biology (01.01.2017)
Get full text
Journal Article
BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment
Piya, Sujan, Mu, Hong, Bhattacharya, Seemana, Lorenzi, Philip L, Davis, R. Eric, McQueen, Teresa, Ruvolo, Vivian, Baran, Natalia, Wang, Zhiqiang, Qian, Yimin, Crews, Craig M, Konopleva, Marina, Ishizawa, Jo, You, M. James, Kantarjian, Hagop, Andreeff, Michael, Borthakur, Gautam
Published in The Journal of clinical investigation (01.05.2019)
Published in The Journal of clinical investigation (01.05.2019)
Get full text
Journal Article
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia
Lin, S, Tian, L, Shen, H, Gu, Y, Li, J-L, Chen, Z, Sun, X, James You, M, Wu, L
Published in Oncogene (03.10.2013)
Published in Oncogene (03.10.2013)
Get full text
Journal Article
EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis
Yang, Weiwei, Xia, Yan, Cao, Yu, Zheng, Yanhua, Bu, Wen, Zhang, Lin, You, M. James, Koh, Mei Yee, Cote, Gilbert, Aldape, Kenneth, Li, Yi, Verma, Inder M., Chiao, Paul J., Lu, Zhimin
Published in Molecular cell (14.12.2012)
Published in Molecular cell (14.12.2012)
Get full text
Journal Article
Cell-to-cell miRNA transfer: from body homeostasis to therapy
Redis, Roxana S, Calin, Steliana, Yang, Yaling, You, M James, Calin, George A
Published in Pharmacology & therapeutics (Oxford) (01.11.2012)
Published in Pharmacology & therapeutics (Oxford) (01.11.2012)
Get full text
Journal Article
Blastoid high-grade B-cell lymphoma initially presenting in bone marrow: a diagnostic challenge
Khanlari, Mahsa, Medeiros, L. Jeffrey, Lin, Pei, Xu, Jie, You, M. James, Tang, Guilin, Yin, C. Cameron, Wang, Wei, Qiu, Lianqun, Miranda, Roberto N., Bueso-Ramos, Carlos E., Li, Shaoying
Published in Modern pathology (01.03.2022)
Published in Modern pathology (01.03.2022)
Get full text
Journal Article
Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways
Kim, Jongchan, Siverly, Ashley N, Chen, Dahu, Wang, Min, Yuan, Yuan, Wang, Yumeng, Lee, Hyemin, Zhang, Jinsong, Muller, William J, Liang, Han, Gan, Boyi, Yang, Xianbin, Sun, Yutong, You, M James, Ma, Li
Published in Cancer research (Chicago, Ill.) (01.11.2016)
Published in Cancer research (Chicago, Ill.) (01.11.2016)
Get full text
Journal Article
Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia
Ferrajoli, Alessandra, Shanafelt, Tait D., Ivan, Cristina, Shimizu, Masayoshi, Rabe, Kari G., Nouraee, Nazila, Ikuo, Mariko, Ghosh, Asish K., Lerner, Susan, Rassenti, Laura Z., Xiao, Lianchun, Hu, Jianhua, Reuben, James M., Calin, Steliana, You, M. James, Manning, John T., Wierda, William G., Estrov, Zeev, O'Brien, Susan, Kipps, Thomas J., Keating, Michael J., Kay, Neil E., Calin, George A.
Published in Blood (12.09.2013)
Published in Blood (12.09.2013)
Get full text
Journal Article
PD-L1 expression is associated with ALK positivity and STAT3 activation, but not outcome in patients with systemic anaplastic large cell lymphoma
Shen, Jing, Li, Shaoying, Medeiros, L. Jeffrey, Lin, Pei, Wang, Sa A., Tang, Guilin, Yin, C. Cameron, You, M. James, Khoury, Joseph D., Iyer, Swaminathan P., Miranda, Roberto N., Xu, Jie
Published in Modern pathology (01.03.2020)
Published in Modern pathology (01.03.2020)
Get full text
Journal Article
Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL
Piya, Sujan, Yang, Yaling, Bhattacharya, Seemana, Sharma, Priyanka, Ma, Huaxian, Mu, Hong, He, Hua, Ruvolo, Vivian, Baran, Natalia, Davis, R. Eric, Jain, Abhinav K., Konopleava, Marina, Kantarjian, Hagop, Andreeff, Michael, You, M. James, Borthakur, Gautam
Published in Leukemia (01.05.2022)
Published in Leukemia (01.05.2022)
Get full text
Journal Article
miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion
Chen, Dahu, Sun, Yutong, Yuan, Yuan, Han, Zhenbo, Zhang, Peijing, Zhang, Jinsong, You, M James, Teruya-Feldstein, Julie, Wang, Min, Gupta, Sumeet, Hung, Mien-Chie, Liang, Han, Ma, Li
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
Get full text
Journal Article