Repetitive Closed-Skull Traumatic Brain Injury in Mice Causes Persistent Multifocal Axonal Injury and Microglial Reactivity
Shitaka, Yoshitsugu, Tran, Hien T, Bennett, Rachel E, Sanchez, Laura, Levy, Marilyn A, Dikranian, Krikor, Brody, David L
Published in Journal of neuropathology and experimental neurology (01.07.2011)
Published in Journal of neuropathology and experimental neurology (01.07.2011)
Get full text
Journal Article
Oxidative stress accelerates amyloid deposition and memory impairment in a double-transgenic mouse model of Alzheimer's disease
Kanamaru, Takuya, Kamimura, Naomi, Yokota, Takashi, Iuchi, Katsuya, Nishimaki, Kiyomi, Takami, Shinya, Akashiba, Hiroki, Shitaka, Yoshitsugu, Katsura, Ken-ichiro, Kimura, Kazumi, Ohta, Shigeo
Published in Neuroscience letters (05.02.2015)
Published in Neuroscience letters (05.02.2015)
Get full text
Journal Article
Intravenous transplantation of bone marrow-derived mononuclear cells prevents memory impairment in transgenic mouse models of Alzheimer’s disease
Kanamaru, Takuya, Kamimura, Naomi, Yokota, Takashi, Nishimaki, Kiyomi, Iuchi, Katsuya, Lee, Hyunjin, Takami, Shinya, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ueda, Masayuki, Katsura, Ken-ichiro, Kimura, Kazumi, Ohta, Shigeo
Published in Brain research (24.04.2015)
Published in Brain research (24.04.2015)
Get full text
Journal Article
Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models
Kohara, Atsuyuki, Takahashi, Masayasu, Yatsugi, Shin-ichi, Tamura, Seiji, Shitaka, Yoshitsugu, Hayashibe, Satoshi, Kawabata, Shigeki, Okada, Masamichi
Published in Brain research (29.01.2008)
Published in Brain research (29.01.2008)
Get full text
Journal Article
Radioligand Binding Properties and Pharmacological Characterization of 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a High-Affinity, Selective, and Noncompetitive Antagonist of Metabotropic Glutamate Receptor Type 1
Kohara, Atsuyuki, Toya, Takashi, Tamura, Seiji, Watabiki, Tomonari, Nagakura, Yukinori, Shitaka, Yoshitsugu, Hayashibe, Satoshi, Kawabata, Shigeki, Okada, Masamichi
Published in The Journal of pharmacology and experimental therapeutics (01.10.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2005)
Get full text
Journal Article
Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models
Kohara, Atsuyuki, Nagakura, Yukinori, Kiso, Tetsuo, Toya, Takashi, Watabiki, Tomonari, Tamura, Seiji, Shitaka, Yoshitsugu, Itahana, Hirotsune, Okada, Masamichi
Published in European journal of pharmacology (24.09.2007)
Published in European journal of pharmacology (24.09.2007)
Get full text
Journal Article
Differential effects between γ-secretase inhibitors and modulators on cognitive function in amyloid precursor protein-transgenic and nontransgenic mice
Mitani, Yasuyuki, Yarimizu, Junko, Saita, Kyoko, Uchino, Hiroshi, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in The Journal of neuroscience (08.02.2012)
Published in The Journal of neuroscience (08.02.2012)
Get full text
Journal Article
P3J4-3 Amelioration of cognitive deficits in AD-model mice with subchronic treatment of a γ-secretase modulator but not inhibitors
Yasuyuki Mitani, Junko Yarimizu, Kyoko Saita, Hiroki Akashiba, Hiroshi Uchino, Yoshitsugu Shitaka, Nobuya Matsuoka
Published in Journal of Pharmacological Sciences (2011)
Get full text
Published in Journal of Pharmacological Sciences (2011)
Journal Article
P1J4-9 Characterization of cognitive impairments of Tg2576 as a mouse model for Alzheimer's disease and effects of donepezil and memantine
Akira Nagakura, Yoshitsugu Shitaka, Junko Yarimizu, Masayasu Takahashi, Akira Miyake, Keni Ni, Nobuya Matsuoka
Published in Journal of Pharmacological Sciences (2011)
Get full text
Published in Journal of Pharmacological Sciences (2011)
Journal Article
P1O-P5-3 Characterization of cognitive deficits of transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine
Akira Nagakura, Junko Yarimizu, Yoshitsugu Shitaka, Akira Miyake, Nobuya Matsuoka
Published in Journal of Pharmacological Sciences (2009)
Get full text
Published in Journal of Pharmacological Sciences (2009)
Journal Article
P2N-33 Antinociceptive effects of YM-230888, a potent, selective and orally-active antagonist of type 1 metabotropic glutamate receptors, at chronic pain models
Atsuyuki Kohara, Yukinori Nagakura, Tetsuo Kiso, Takashi Toya, Seiji Tamura, Tomonari Watabiki, Yoshitsugu Shitaka, Hirotsune Itahana, Masamichi Okada
Published in Journal of Pharmacological Sciences (2006)
Get full text
Published in Journal of Pharmacological Sciences (2006)
Journal Article
Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble A beta 42 without affecting other A beta pools
Mitani, Yasuyuki, Yarimizu, Junko, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in Journal of neurochemistry (01.05.2013)
Published in Journal of neurochemistry (01.05.2013)
Get full text
Journal Article
Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer's disease, in rodents and nonhuman primates
Mitani, Yasuyuki, Akashiba, Hiroki, Saita, Kyoko, Yarimizu, Junko, Uchino, Hiroshi, Okabe, Mayuko, Asai, Makoto, Yamasaki, Shingo, Nozawa, Takashi, Ishikawa, Noritoshi, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in Neuropharmacology (01.04.2014)
Published in Neuropharmacology (01.04.2014)
Get full text
Journal Article
Amelioration of cognitive deficits in plaque‐bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools
Mitani, Yasuyuki, Yarimizu, Junko, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in Journal of neurochemistry (01.05.2013)
Published in Journal of neurochemistry (01.05.2013)
Get full text
Journal Article
Amelioration of cognitive deficits in plaque‐bearing A lzheimer's disease model mice through selective reduction of nascent soluble A42 without affecting other A pools
Mitani, Yasuyuki, Yarimizu, Junko, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in Journal of neurochemistry (01.05.2013)
Published in Journal of neurochemistry (01.05.2013)
Get full text
Journal Article
Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble A[beta]42 without affecting other A[beta] pools
Mitani, Yasuyuki, Yarimizu, Junko, Akashiba, Hiroki, Shitaka, Yoshitsugu, Ni, Keni, Matsuoka, Nobuya
Published in Journal of neurochemistry (01.05.2013)
Published in Journal of neurochemistry (01.05.2013)
Get full text
Journal Article
P1‐143: Characterization of cognitive functions of Tg2576 mouse model for Alzheimer's disease with multiple cognitive tasks
Nagakura, Akira, Yarimizu, Junko, Takahashi, Masayasu, Shitaka, Yoshitsugu, Miyake, Akira, Matsuoka, Nobuya
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
Get full text
Journal Article
Characterization of cognitive functions of Tg2576 mouse model for Alzheimer's disease with multiple cognitive tasks
Nagakura, Akira, Yarimizu, Junko, Takahashi, Masayasu, Shitaka, Yoshitsugu, Miyake, Akira, Matsuoka, Nobuya
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
Get full text
Journal Article