Comparative hepatotoxicity of a herbicide, epyrifenacil, in humans and rodents by comparing the dynamics and kinetics of its causal metabolite
Matsunaga, Kohei, Fukunaga, Satoki, Abe, Jun, Takeuchi, Hayato, Kitamoto, Sachiko, Tomigahara, Yoshitaka
Published in Journal of Pesticide Science (20.11.2021)
Published in Journal of Pesticide Science (20.11.2021)
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Journal Article
Lack of human relevance for rat developmental toxicity of flumioxazin is revealed by comparative heme synthesis assay using embryonic erythroid cells derived from human and rat pluripotent stem cells
Asano, Koji, Takahashi, Yasuhiko, Ueno, Manako, Fukuda, Takako, Otani, Mitsuhiro, Kitamoto, Sachiko, Tomigahara, Yoshitaka
Published in Journal of toxicological sciences (01.01.2022)
Published in Journal of toxicological sciences (01.01.2022)
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Journal Article
Identification of Metabolism and Excretion Differences of Procymidone between Rats and Humans Using Chimeric Mice: Implications for Differential Developmental Toxicity
Abe, Jun, Tomigahara, Yoshitaka, Tarui, Hirokazu, Omori, Rie, Kawamura, Satoshi
Published in Journal of agricultural and food chemistry (28.02.2018)
Published in Journal of agricultural and food chemistry (28.02.2018)
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Journal Article
Metabolism of (Z)‑(1R,3R)‑Profluthrin in Rats
Abe, Jun, Nagahori, Hirohisa, Omori, Rie, Mikata, Kazuki, Kurosawa, Motohiro, Tomigahara, Yoshitaka, Isobe, Naohiko
Published in Journal of agricultural and food chemistry (07.10.2015)
Published in Journal of agricultural and food chemistry (07.10.2015)
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Journal Article
Lack of human relevance for procymidone’s developmental toxicity attributable to species difference in its kinetics and metabolism
Tomigahara, Yoshitaka, Tarui, Hirokazu, Matsui, Masayoshi, Kurosawa, Motohiro, Kawamura, Satoshi, Isobe, Naohiko
Published in Journal of Pesticide Science (20.05.2018)
Published in Journal of Pesticide Science (20.05.2018)
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Journal Article
Cooperativity between DNA Methyltransferases in the Maintenance Methylation of Repetitive Elements
Liang, Gangning, Chan, Matilda F., Tomigahara, Yoshitaka, Tsai, Yvonne C., Gonzales, Felicidad A., Li, En, Laird, Peter W., Jones, Peter A.
Published in Molecular and Cellular Biology (01.01.2002)
Published in Molecular and Cellular Biology (01.01.2002)
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Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation
Deguchi, Yoshihito, Yamada, Tomoya, Hirose, Yukihiro, Nagahori, Hirohisa, Kushida, Masahiko, Sumida, Kayo, Sukata, Tokuo, Tomigahara, Yoshitaka, Nishioka, Kazuhiko, Uwagawa, Satoshi, Kawamura, Satoshi, Okuno, Yasuyoshi
Published in Toxicological sciences (01.03.2009)
Published in Toxicological sciences (01.03.2009)
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Journal Article
Anti-androgenic activity of procymidone and its metabolites
Tomigahara, Yoshitaka, Suzuki, Noriyuki, Tarui, Hirokazu, Saito, Koichi, Kaneko, Hideo
Published in Journal of Pesticide Science (01.01.2014)
Published in Journal of Pesticide Science (01.01.2014)
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Journal Article
Metabolism of Procymidone Derivatives in Female Rats
Tarui, Hirokazu, Abe, Jun, Tomigahara, Yoshitaka, Kawamura, Satoshi, Kaneko, Hideo
Published in Journal of agricultural and food chemistry (25.11.2009)
Published in Journal of agricultural and food chemistry (25.11.2009)
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Journal Article
Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes
Hirose, Yukihiro, Nagahori, Hirohisa, Yamada, Tomoya, Deguchi, Yoshihito, Tomigahara, Yoshitaka, Nishioka, Kazuhiko, Uwagawa, Satoshi, Kawamura, Satoshi, Isobe, Naohiko, Lake, Brian G, Okuno, Yasuyoshi
Published in Toxicology (Amsterdam) (05.04.2009)
Published in Toxicology (Amsterdam) (05.04.2009)
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Journal Article
Metabolism of Pyridalyl in Rats
NAGAHORI, Hirohisa, SAITO, Koichi, TOMIGAHARA, Yoshitaka, ISOBE, Naohiko, KANEKO, Hideo
Published in Drug metabolism and disposition (01.12.2009)
Published in Drug metabolism and disposition (01.12.2009)
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Journal Article
Metabolism of 2,6-Dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl Ether (Pyridalyl) in Rats after Repeated Oral Administration and a Simple Physiologically Based Pharmacokinetic Modeling in Brown and White Adipose Tissues
NAGAHORI, Hirohisa, MATSUNAGA, Haruyuki, TOMIGAHARA, Yoshitaka, ISOBE, Naohiko, KANEKO, Hideo
Published in Drug metabolism and disposition (01.05.2010)
Published in Drug metabolism and disposition (01.05.2010)
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Journal Article
Species differences in the developmental toxicity of procymidone: Remarkable variation in pharmacokinetics, metabolism, and excretion
Tomigahara, Yoshitaka, Tarui, Hirokazu, Nagahori, Hirohisa, Sugimoto, Kenji, Mogi, Masayuki, Nishioka, Kazuhiko, Kawamura, Satoshi, Isobe, Naohiko, Okuno, Yasuyoshi, Kaneko, Hideo
Published in Journal of Pesticide Science (01.01.2015)
Published in Journal of Pesticide Science (01.01.2015)
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Journal Article
Metabolism of Flufenpyr-ethyl in Rats and Mice
Nagahori, Hirohisa, Matsunaga, Haruyuki, Tomigahara, Yoshitaka, Isobe, Naohiko, Kaneko, Hideo
Published in Journal of agricultural and food chemistry (10.06.2009)
Published in Journal of agricultural and food chemistry (10.06.2009)
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Journal Article
Species differences in the developmental toxicity of procymidone—Placental transfer of procymidone in pregnant rats, rabbits, and monkeys
Tarui, Hirokazu, Tomigahara, Yoshitaka, Nagahori, Hirohisa, Sugimoto, Kenji, Mogi, Masayuki, Kawamura, Satoshi, Isobe, Naohiko, Kaneko, Hideo
Published in Journal of Pesticide Science (20.05.2018)
Published in Journal of Pesticide Science (20.05.2018)
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Journal Article
Metabolism of Furametpyr. 1. Identification of Metabolites and in Vitro Biotransformation in Rats and Humans
Nagahori, Hirohisa, Yoshino, Hiromi, Tomigahara, Yoshitaka, Isobe, Naohiko, Kaneko, Hideo, Nakatsuka, Iwao
Published in Journal of agricultural and food chemistry (01.11.2000)
Published in Journal of agricultural and food chemistry (01.11.2000)
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Journal Article
O3F-1-5 A novel small compound that promotes nuclear translocation of YB-1 suppresses experimental hepatic fibrosis in mice
Kiyoshi Higashi, Yoshitaka Tomigahara, Hiroaki Shiraki, Kazuhiko Nishioka, Kaori Miyata, Toshiyuki Mikami, Toru Kimura, Yutaka Inagaki, Hideo Kaneko
Published in Journal of Pharmacological Sciences (2010)
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Published in Journal of Pharmacological Sciences (2010)
Journal Article
Metabolism of metofluthrin in rats: I. Identification of metabolites
Abe, Jun, Nagahori, Hirohisa, Tarui, Hirokazu, Tomigahara, Yoshitaka, Isobe, Naohiko
Published in Xenobiotica (01.02.2018)
Published in Xenobiotica (01.02.2018)
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