Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
Faust, Tyler B., Yoon, Hojong, Nowak, Radosław P., Donovan, Katherine A., Li, Zhengnian, Cai, Quan, Eleuteri, Nicholas A., Zhang, Tinghu, Gray, Nathanael S., Fischer, Eric S.
Published in Nature chemical biology (01.01.2020)
Published in Nature chemical biology (01.01.2020)
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Journal Article
Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor
Yoon, Hojong, Shin, Injae, Nam, Yunju, Kim, Nam Doo, Lee, Kyung-Bok, Sim, Taebo
Published in European journal of medicinal chemistry (05.01.2017)
Published in European journal of medicinal chemistry (05.01.2017)
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Journal Article
Asymmetric Synthesis of (-)-6-Desmethyl-Fluvirucinine A₁ via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions
Moon, Hyunyoung, Yoon, Hojong, Lim, Changjin, Jang, Jaebong, Yi, Jong-Jae, Lee, Jae Kyun, Lee, Jeeyeon, Na, Younghwa, Son, Woo Sung, Kim, Seok-Ho, Suh, Young-Ger
Published in Molecules (Basel, Switzerland) (14.09.2018)
Published in Molecules (Basel, Switzerland) (14.09.2018)
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Journal Article
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein
Zou, Charles, Yoon, Hojong, Park, Paul M.C., Patten, J.J., Pellman, Jesse, Carreiro, Jeannie, Tsai, Jonathan M., Li, Yen-Der, Roy Burman, Shourya S., Donovan, Katherine A., Gasser, Jessica, Sperling, Adam S., Nowak, Radosław P., Fischer, Eric S., Davey, Robert A., Ebert, Benjamin L., Słabicki, Mikołaj
Published in iScience (19.05.2023)
Published in iScience (19.05.2023)
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Journal Article
Small-molecule-induced polymerization triggers degradation of BCL6
Słabicki, Mikołaj, Yoon, Hojong, Koeppel, Jonas, Nitsch, Lena, Roy Burman, Shourya S., Di Genua, Cristina, Donovan, Katherine A., Sperling, Adam S., Hunkeler, Moritz, Tsai, Jonathan M., Sharma, Rohan, Guirguis, Andrew, Zou, Charles, Chudasama, Priya, Gasser, Jessica A., Miller, Peter G., Scholl, Claudia, Fröhling, Stefan, Nowak, Radosław P., Fischer, Eric S., Ebert, Benjamin L.
Published in Nature (London) (03.12.2020)
Published in Nature (London) (03.12.2020)
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Journal Article
Induced protein degradation for therapeutics: past, present, and future
Yoon, Hojong, Rutter, Justine C, Li, Yen-Der, Ebert, Benjamin L
Published in The Journal of clinical investigation (01.01.2024)
Published in The Journal of clinical investigation (01.01.2024)
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Journal Article
A Pyrazolo[3,4‑d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants
Yoon, Hojong, Kwak, Yeonui, Choi, Seunghye, Cho, Hanna, Kim, Nam Doo, Sim, Taebo
Published in Journal of medicinal chemistry (14.01.2016)
Published in Journal of medicinal chemistry (14.01.2016)
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Journal Article
Exploring the target scope of KEAP1 E3 ligase-based PROTACs
Du, Guangyan, Jiang, Jie, Henning, Nathaniel J, Safaee, Nozhat, Koide, Eriko, Nowak, Radosław P, Donovan, Katherine A, Yoon, Hojong, You, Inchul, Yue, Hong, Eleuteri, Nicholas A, He, Zhixiang, Li, Zhengnian, Huang, Hubert T, Che, Jianwei, Nabet, Behnam, Zhang, Tinghu, Fischer, Eric S, Gray, Nathanael S
Published in Cell chemical biology (20.10.2022)
Published in Cell chemical biology (20.10.2022)
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Journal Article
Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3
Cho, Hanna, Shin, Injae, Yoon, Hojong, Jeon, Eunhye, Lee, Jiwon, Kim, Younghoon, Ryu, Seong Shick, Song, Chiman, Kwon, Nam Hoon, Moon, Youngji, Kim, Sunghoon, Kim, Nam Doo, Choi, Hwan Geun, Sim, Taebo
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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Journal Article
Polymerization of ZBTB transcription factors regulates chromatin occupancy
Park, Paul M.C., Park, Jiho, Brown, Jared, Hunkeler, Moritz, Roy Burman, Shourya S., Donovan, Katherine A., Yoon, Hojong, Nowak, Radosław P., Słabicki, Mikołaj, Ebert, Benjamin L., Fischer, Eric S.
Published in Molecular cell (11.07.2024)
Published in Molecular cell (11.07.2024)
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Journal Article
Template-assisted covalent modification underlies activity of covalent molecular glues
Li, Yen-Der, Ma, Michelle W, Hassan, Muhammad Murtaza, Hunkeler, Moritz, Teng, Mingxing, Puvar, Kedar, Rutter, Justine C, Lumpkin, Ryan J, Sandoval, Brittany, Jin, Cyrus Y, Schmoker, Anna M, Ficarro, Scott B, Cheong, Hakyung, Metivier, Rebecca J, Wang, Michelle Y, Xu, Shawn, Byun, Woong Sub, Groendyke, Brian J, You, Inchul, Sigua, Logan H, Tavares, Isidoro, Zou, Charles, Tsai, Jonathan M, Park, Paul M C, Yoon, Hojong, Majewski, Felix C, Sperling, Haniya T, Marto, Jarrod A, Qi, Jun, Nowak, Radosław P, Donovan, Katherine A, Słabicki, Mikołaj, Gray, Nathanael S, Fischer, Eric S, Ebert, Benjamin L
Published in Nature chemical biology (29.07.2024)
Published in Nature chemical biology (29.07.2024)
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Journal Article
Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors
Cho, Hanna, Shin, Injae, Cho, Kyungseon, Yoon, Hojong, Yoo, Eun Kyung, Kim, Mi-Jin, Park, Sungmi, Lee, In-Kyu, Kim, Nam Doo, Sim, Taebo
Published in Journal of medicinal chemistry (26.09.2019)
Published in Journal of medicinal chemistry (26.09.2019)
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Journal Article
Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface
Teng, Mingxing, Ficarro, Scott B., Yoon, Hojong, Che, Jianwei, Zhou, Jing, Fischer, Eric S., Marto, Jarrod A., Zhang, Tinghu, Gray, Nathanael S.
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Journal Article
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence
Wu, Gongwei, Yoshida, Noriaki, Liu, Jihe, Zhang, Xiaoyang, Xiong, Yuan, Heavican-Foral, Tayla B, Mandato, Elisa, Liu, Huiyun, Nelson, Geoffrey M, Yang, Lu, Chen, Renee, Donovan, Katherine A, Jones, Marcus K, Roshal, Mikhail, Zhang, Yanming, Xu, Ran, Nirmal, Ajit J, Jain, Salvia, Leahy, Catharine, Jones, Kristen L, Stevenson, Kristen E, Galasso, Natasha, Ganesan, Nivetha, Chang, Tiffany, Wu, Wen-Chao, Louissaint, Abner, Debaize, Lydie, Yoon, Hojong, Dal Cin, Paola, Chan, Wing C, Ho Sui, Shannan J, Ng, Samuel Y, Feldman, Andrew L, Horwitz, Steven M, Adelman, Karen, Fischer, Eric S, Chen, Chun-Wei, Weinstock, David M, Brown, Myles
Published in Science translational medicine (20.09.2023)
Published in Science translational medicine (20.09.2023)
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Journal Article
BTBBCL6 dimers as building blocks for reversible drug-induced protein oligomerization
Nitsch, Lena, Jensen, Patrizia, Yoon, Hojong, Koeppel, Jonas, Burman, Shourya Sonkar Roy, Fischer, Eric Sebastian, Scholl, Claudia, Fröhling, Stefan, Słabicki, Mikołaj
Published in Cell reports methods (25.04.2022)
Published in Cell reports methods (25.04.2022)
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Journal Article
In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3
Hwang, Gyoyeon, Kim, Hyeonhye, Yoon, Hojong, Song, Chiman, Lim, Dong-Kwon, Sim, Taebo, Lee, Jiyeon
Published in International journal of nanomedicine (01.01.2017)
Published in International journal of nanomedicine (01.01.2017)
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