Factor VIII–Mimetic Function of Humanized Bispecific Antibody in Hemophilia A
Shima, Midori, Hanabusa, Hideji, Taki, Masashi, Matsushita, Tadashi, Sato, Tetsuji, Fukutake, Katsuyuki, Fukazawa, Naoki, Yoneyama, Koichiro, Yoshida, Hiroki, Nogami, Keiji
Published in The New England journal of medicine (26.05.2016)
Published in The New England journal of medicine (26.05.2016)
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Journal Article
A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A
Yoneyama, Koichiro, Schmitt, Christophe, Kotani, Naoki, Levy, Gallia G., Kasai, Ryu, Iida, Satofumi, Shima, Midori, Kawanishi, Takehiko
Published in Clinical pharmacokinetics (01.09.2018)
Published in Clinical pharmacokinetics (01.09.2018)
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Journal Article
Long-term safety and efficacy of emicizumab in a phase 1/2 study in patients with hemophilia A with or without inhibitors
Shima, Midori, Hanabusa, Hideji, Taki, Masashi, Matsushita, Tadashi, Sato, Tetsuji, Fukutake, Katsuyuki, Kasai, Ryu, Yoneyama, Koichiro, Yoshida, Hiroki, Nogami, Keiji
Published in Blood advances (10.10.2017)
Published in Blood advances (10.10.2017)
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Journal Article
Relative and Absolute Bioavailability Study of Emicizumab to Bridge Drug Products and Subcutaneous Injection Sites in Healthy Volunteers
Kotani, Naoki, Yoneyama, Koichiro, Kawakami, Nobuhiko, Shimuta, Tohru, Fukase, Hiroyuki, Kawanishi, Takehiko
Published in Clinical pharmacology in drug development (01.08.2019)
Published in Clinical pharmacology in drug development (01.08.2019)
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Journal Article
A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?
Chiba, Koji, Yoshitsugu, Hiroyuki, Kyosaka, Yuto, Iida, Satofumi, Yoneyama, Koichiro, Tanigawa, Takahiko, Fukushima, Takashi, Hiraoka, Masaki
Published in Journal of clinical pharmacology (01.05.2014)
Published in Journal of clinical pharmacology (01.05.2014)
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Journal Article
Characterization of Anti-Emicizumab Antibodies Using Repository Samples Obtained in Clinical Studies of Emicizumab Conducted in Japan
Matsumoto, Naoki, Abe, Hiroto, Kawasaki, Ryohei, Tashiro, Yoshihito, Noguchi-Sasaki, Mariko, Harada, Suguru, Yoneyama, Koichiro, Niino, Tomomi, Soeda, Tetsuhiro, Yoshimura, Yasushi
Published in TH open : companion journal to thrombosis and haemostasis (01.07.2023)
Published in TH open : companion journal to thrombosis and haemostasis (01.07.2023)
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Journal Article
A multicentre, open‐label study of emicizumab given every 2 or 4 weeks in children with severe haemophilia A without inhibitors
Shima, Midori, Nogami, Keiji, Nagami, Sayaka, Yoshida, Seitaro, Yoneyama, Koichiro, Ishiguro, Akira, Suzuki, Takashi, Taki, Masashi
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2019)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2019)
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Journal Article
A Healthy Volunteer-Derived, Factor VIII-Neutralized, Acquired Hemophilia a-Mimetic Plasma Produces Similar Pharmacodynamic Responses of Emicizumab to Those in Patients with Congenital Hemophilia a with or without Inhibitors
Yoneyama, Koichiro, Tokuda, Kazuo, Soeda, Tetsuhiro, Saito, Tomohisa, Shima, Midori
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Quantitative Estimation of the In Vivo Equivalent Factor VIII Activity of NXT007, an Emicizumab-Based, Next-Generation, Activated Factor VIII-Mimetic Bispecific Antibody, from Nonclinical Data
Yoneyama, Koichiro, Soeda, Tetsuhiro, Yamaguchi, Kazuki, Miwa, Takuya, Ishida, Takaaki, Saito, Tomohisa
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
A prospective, multicenter, open-label phase III study of emicizumab prophylaxis in patients with acquired hemophilia A
Shima, Midori, Amano, Kagehiro, Ogawa, Yoshiyuki, Yoneyama, Koichiro, Ozaki, Ryoto, Kobayashi, Ryota, Sakaida, Emiko, Saito, Makoto, Okamura, Takashi, Ito, Toshihiro, Hattori, Norimichi, Higasa, Satoshi, Suzuki, Nobuaki, Seki, Yoshinobu, Nogami, Keiji
Published in Journal of thrombosis and haemostasis (01.03.2023)
Published in Journal of thrombosis and haemostasis (01.03.2023)
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Journal Article
A Model‐Based Framework to Inform the Dose Selection and Study Design of Emicizumab for Pediatric Patients With Hemophilia A
Yoneyama, Koichiro, Schmitt, Christophe, Chang, Tiffany, Dhalluin, Christophe, Nagami, Sayaka, Petry, Claire, Levy, Gallia G.
Published in Journal of clinical pharmacology (01.02.2022)
Published in Journal of clinical pharmacology (01.02.2022)
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Journal Article
An Investigational Dosing Algorithm of Emicizumab for Prophylaxis in Acquired Hemophilia a
Shima, Midori, Nagami, Sayaka, Yoneyama, Koichiro, Nomura, Akira, Ogawa, Yoshiyuki, Amano, Kagehiro, Nogami, Keiji
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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