Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease
Litvinchuk, Alexandra, Wan, Ying-Wooi, Swartzlander, Dan B., Chen, Fading, Cole, Allysa, Propson, Nicholas E., Wang, Qian, Zhang, Bin, Liu, Zhandong, Zheng, Hui
Published in Neuron (Cambridge, Mass.) (19.12.2018)
Published in Neuron (Cambridge, Mass.) (19.12.2018)
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Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides
Sztainberg, Yehezkel, Chen, Hong-mei, Swann, John W., Hao, Shuang, Tang, Bin, Wu, Zhenyu, Tang, Jianrong, Wan, Ying-Wooi, Liu, Zhandong, Rigo, Frank, Zoghbi, Huda Y.
Published in Nature (London) (03.12.2015)
Published in Nature (London) (03.12.2015)
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TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading
Martini-Stoica, Heidi, Cole, Allysa L, Swartzlander, Daniel B, Chen, Fading, Wan, Ying-Wooi, Bajaj, Lakshya, Bader, David A, Lee, Virginia M Y, Trojanowski, John Q, Liu, Zhandong, Sardiello, Marco, Zheng, Hui
Published in The Journal of experimental medicine (03.09.2018)
Published in The Journal of experimental medicine (03.09.2018)
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Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors
Patel, Akash J., Wan, Ying-Wooi, Al-Ouran, Rami, Revelli, Jean-Pierre, Cardenas, Maria F., Oneissi, Mazen, Xi, Liu, Jalali, Ali, Magnotti, John F., Muzny, Donna M., Doddapaneni, HarshaVardhan, Sebastian, Sherly, Heck, Kent A., Goodman, J. Clay, Gopinath, Shankar P., Liu, Zhandong, Rao, Ganesh, Plon, Sharon E., Yoshor, Daniel, Wheeler, David A., Zoghbi, Huda Y., Klisch, Tiemo J.
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2019)
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Serine catabolism regulates mitochondrial redox control during hypoxia
Ye, Jiangbin, Fan, Jing, Venneti, Sriram, Wan, Ying-Wooi, Pawel, Bruce R, Zhang, Ji, Finley, Lydia W S, Lu, Chao, Lindsten, Tullia, Cross, Justin R, Qing, Guoliang, Liu, Zhandong, Simon, M Celeste, Rabinowitz, Joshua D, Thompson, Craig B
Published in Cancer discovery (01.12.2014)
Published in Cancer discovery (01.12.2014)
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Digital sorting of complex tissues for cell type-specific gene expression profiles
Zhong, Yi, Wan, Ying-Wooi, Pang, Kaifang, Chow, Lionel M L, Liu, Zhandong
Published in BMC bioinformatics (07.03.2013)
Published in BMC bioinformatics (07.03.2013)
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MATR3 pathogenic variants differentially impair its cryptic splicing repression function
Khan, Mashiat, Chen, Xiao Xiao Lily, Dias, Michelle, Santos, Jhune Rizsan, Kour, Sukhleen, You, Justin, Bruggen, Rebekah, Youssef, Mohieldin M. M., Wan, Ying‐Wooi, Liu, Zhandong, Rosenfeld, Jill A., Tan, Qiumin, Pandey, Udai Bhan, Yalamanchili, Hari Krishna, Park, Jeehye
Published in FEBS letters (01.02.2024)
Published in FEBS letters (01.02.2024)
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Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation
Sun, Jialin, Osenberg, Sivan, Irwin, Austin, Ma, Li-Hua, Lee, Nigel, Xiang, Yangfei, Li, Feng, Wan, Ying-Wooi, Park, In-Hyun, Maletic-Savatic, Mirjana, Ballas, Nurit
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism
Rousseaux, Maxime W.C., Tschumperlin, Tyler, Lu, Hsiang-Chih, Lackey, Elizabeth P., Bondar, Vitaliy V., Wan, Ying-Wooi, Tan, Qiumin, Adamski, Carolyn J., Friedrich, Jillian, Twaroski, Kirk, Chen, Weili, Tolar, Jakub, Henzler, Christine, Sharma, Ajay, Bajić, Aleksandar, Lin, Tao, Duvick, Lisa, Liu, Zhandong, Sillitoe, Roy V., Zoghbi, Huda Y., Orr, Harry T.
Published in Neuron (Cambridge, Mass.) (21.03.2018)
Published in Neuron (Cambridge, Mass.) (21.03.2018)
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Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity
Pohodich, Amy E, Yalamanchili, Hari, Raman, Ayush T, Wan, Ying-Wooi, Gundry, Michael, Hao, Shuang, Jin, Haijing, Tang, Jianrong, Liu, Zhandong, Zoghbi, Huda Y
Published in eLife (23.03.2018)
Published in eLife (23.03.2018)
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Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1
Lee, Won‐Seok, Lavery, Laura, Rousseaux, Maxime W C, Rutledge, Eric B, Jang, Youjin, Wan, Ying‐Wooi, Wu, Sih‐Rong, Kim, Wonho, Al‐Ramahi, Ismael, Rath, Smruti, Adamski, Carolyn J, Bondar, Vitaliy V, Tewari, Ambika, Soleimani, Shirin, Mota, Samantha, Yalamanchili, Hari K, Orr, Harry T, Liu, Zhandong, Botas, Juan, Zoghbi, Huda Y
Published in The EMBO journal (01.04.2021)
Published in The EMBO journal (01.04.2021)
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Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models
Tan, Qiumin, Yalamanchili, Hari Krishna, Park, Jeehye, De Maio, Antonia, Lu, Hsiang-Chih, Wan, Ying-Wooi, White, Joshua J, Bondar, Vitaliy V, Sayegh, Layal S, Liu, Xiuyun, Gao, Yan, Sillitoe, Roy V, Orr, Harry T, Liu, Zhandong, Zoghbi, Huda Y
Published in Human molecular genetics (01.12.2016)
Published in Human molecular genetics (01.12.2016)
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Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus–CA3 projection
Zhou, Wenjun, He, Yanlin, Rehman, Atteeq U, Kong, Yan, Hong, Sungguan, Ding, Guolian, Yalamanchili, Hari Krishna, Wan, Ying-Wooi, Paul, Basil, Wang, Chuhan, Gong, Yingyun, Zhou, Wenxian, Liu, Hao, Dean, John, Scalais, Emmanuel, O’Driscoll, Mary, Morton, Jenny E. V, Hou, Xinguo, Wu, Qi, Tong, Qingchun, Liu, Zhandong, Liu, Pengfei, Xu, Yong, Sun, Zheng
Published in Nature neuroscience (01.02.2019)
Published in Nature neuroscience (01.02.2019)
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Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome
Lavery, Laura A, Ure, Kerstin, Wan, Ying-Wooi, Luo, Chongyuan, Trostle, Alexander J, Wang, Wei, Jin, Haijing, Lopez, Joanna, Lucero, Jacinta, Durham, Mark A, Castanon, Rosa, Nery, Joseph R, Liu, Zhandong, Goodell, Margaret, Ecker, Joseph R, Behrens, M Margarita, Zoghbi, Huda Y
Published in eLife (11.03.2020)
Published in eLife (11.03.2020)
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Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations
Raman, Ayush T., Pohodich, Amy E., Wan, Ying-Wooi, Yalamanchili, Hari Krishna, Lowry, William E., Zoghbi, Huda Y., Liu, Zhandong
Published in Nature communications (13.08.2018)
Published in Nature communications (13.08.2018)
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MicroRNA, mRNA, and Proteomics Biomarkers and Therapeutic Targets for Improving Lung Cancer Treatment Outcomes
Ye, Qing, Raese, Rebecca, Luo, Dajie, Cao, Shu, Wan, Ying-Wooi, Qian, Yong, Guo, Nancy Lan
Published in Cancers (14.04.2023)
Published in Cancers (14.04.2023)
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