Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts
Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Diabetes (New York, N.Y.) (01.06.2004)
Published in Diabetes (New York, N.Y.) (01.06.2004)
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Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN
Yang, Yanwu, Petkova, Aneta, Huang, Kun, Xu, Bin, Hua, Qing-xin, Ye, I. Ju, Chu, Ying-Chi, Hu, Shi-Quan, Phillips, Nelson B, Whittaker, Jonathan, Ismail-Beigi, Faramarz, Mackin, Robert B, Katsoyannis, Panayotis G, Tycko, Robert, Weiss, Michael A
Published in The Journal of biological chemistry (02.04.2010)
Published in The Journal of biological chemistry (02.04.2010)
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Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities
Weiss, Michael A., Hua, Qing-Xin, Jia, Wenhua, Nakagawa, Satoe H., Chu, Ying-Chi, Hu, Shi-Quan, Katsoyannis, Panayotis G.
Published in The Journal of biological chemistry (26.10.2001)
Published in The Journal of biological chemistry (26.10.2001)
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Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS
Xu, Bin, Huang, Kun, Chu, Ying-Chi, Hu, Shi-Quan, Nakagawa, Satoe, Wang, Shuhua, Wang, Run-Ying, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (22.05.2009)
Published in The Journal of biological chemistry (22.05.2009)
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Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activity
Liu, Ming, Wan, Zhu-Li, Chu, Ying-Chi, Aladdin, Hassan, Klaproth, Birgit, Choquette, Meredith, Hua, Qing-Xin, Mackin, Robert B, Rao, J Sunil, De Meyts, Pierre, Katsoyannis, Panayotis G, Arvan, Peter, Weiss, Michael A
Published in The Journal of biological chemistry (11.12.2009)
Published in The Journal of biological chemistry (11.12.2009)
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A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE
Huang, Kun, Chan, Shu Jin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Klaproth, Birgit, Jia, Wenhua, Whittaker, Jonathan, De Meyts, Pierre, Nakagawa, Satoe H, Steiner, Donald F, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (30.11.2007)
Published in The Journal of biological chemistry (30.11.2007)
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How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor
Huang, Kun, Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Hua, Qing-Xin, Qu, Yan, Li, Biaoru, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Theede, Anne Mette, Whittaker, Jonathan, De Meyts, Pierre, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (06.08.2004)
Published in Journal of molecular biology (06.08.2004)
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Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama
Wan, Zhu-li, Huang, Kun, Xu, Bin, Hu, Shi-Quan, Wang, Shuhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (05.04.2005)
Published in Biochemistry (Easton) (05.04.2005)
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Journal Article
Diabetes-Associated Mutations in Insulin: Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor
Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Huang, Kun, Nakagawa, Satoe H, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (06.07.2004)
Published in Biochemistry (Easton) (06.07.2004)
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Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing
Hua, Qing-Xin, Chu, Ying-Chi, Jia, Wenhua, Phillips, Nelson F B, Wang, Run-Ying, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (08.11.2002)
Published in The Journal of biological chemistry (08.11.2002)
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Enhancing the Activity of Insulin at the Receptor Interface: Crystal Structure and Photo-Cross-Linking of A8 Analogues
Wan, Zhuli, Xu, Bin, Huang, Kun, Chu, Ying-Chi, Li, Biaoru, Nakagawa, Satoe H, Qu, Yan, Hu, Shi-Quan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (28.12.2004)
Published in Biochemistry (Easton) (28.12.2004)
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Crystal Structure of a “Nonfoldable” Insulin
Liu, Ming, Wan, Zhu-li, Chu, Ying-Chi, Aladdin, Hassan, Klaproth, Birgit, Choquette, Meredith, Hua, Qing-xin, Mackin, Robert B., Rao, J.Sunil, De Meyts, Pierre, Katsoyannis, Panayotis G., Arvan, Peter, Weiss, Michael A.
Published in The Journal of biological chemistry (01.12.2009)
Published in The Journal of biological chemistry (01.12.2009)
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Journal Article
Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning
Xu, Bin, Huang, Kun, Chu, Ying-Chi, Hu, Shi-Quan, Nakagawa, Satoe, Wang, Shuhua, Wang, Run-Ying, Whittaker, Jonathan, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (22.05.2009)
Published in The Journal of biological chemistry (22.05.2009)
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Journal Article
Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue
Xu, Bin, Hua, Qing-xin, Nakagawa, Satoe H, Jia, Wenhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (22.02.2002)
Published in Journal of molecular biology (22.02.2002)
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Journal Article
The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor
Huang, Kun, Chan, Shu Jin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Klaproth, Birgit, Jia, Wenhua, Whittaker, Jonathan, De Meyts, Pierre, Nakagawa, Satoe H., Steiner, Donald F., Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (30.11.2007)
Published in The Journal of biological chemistry (30.11.2007)
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Journal Article
Mapping the Functional Surface of Insulin by Design: Structure and Function of a Novel A-Chain Analogue
Hua, Qing-Xin, Hu, Shi-Quan, Frank, Bruce H., Jia, Wenhua, Chu, Ying-Chi, Wang, Shu-Hua, Burke, G.Thompson, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in Journal of molecular biology (29.11.1996)
Published in Journal of molecular biology (29.11.1996)
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Protein Structure and the Spandrels of San Marco: Insulin's Receptor-Binding Surface Is Buttressed by an Invariant Leucine Essential for Its Stability
Weiss, Michael A, Nakagawa, Satoe H, Jia, Wenhua, Xu, Bin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Katsoyannis, Panayotis G
Published in Biochemistry (Easton) (22.01.2002)
Published in Biochemistry (Easton) (22.01.2002)
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Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor
Weiss, Michael A, Wan, Zhuli, Zhao, Ming, Chu, Ying-Chi, Nakagawa, Satoe H, Burke, G Thomson, Jia, Wenhua, Hellmich, Rosanna, Katsoyannis, Panayotis G
Published in Journal of molecular biology (11.01.2002)
Published in Journal of molecular biology (11.01.2002)
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Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures
Hua, Qing-Xin, Hu, Shi-Quan, Jia, Wenhua, Chu, Ying-Chi, Burke, G.Thompson, Wang, Shu-Hua, Wang, Run-Ying, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in Journal of molecular biology (20.03.1998)
Published in Journal of molecular biology (20.03.1998)
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