NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity
Moriyama, Takaya, Nishii, Rina, Perez-Andreu, Virginia, Yang, Wenjian, Klussmann, Federico Antillon, Zhao, Xujie, Lin, Ting-Nien, Hoshitsuki, Keito, Nersting, Jacob, Kihira, Kentaro, Hofmann, Ute, Komada, Yoshihiro, Kato, Motohiro, McCorkle, Robert, Li, Lie, Koh, Katsuyoshi, Najera, Cesar Rolando, Kham, Shirley Kow-Yin, Isobe, Tomoya, Chen, Zhiwei, Chiew, Edwynn Kean-Hui, Bhojwani, Deepa, Jeffries, Cynthia, Lu, Yan, Schwab, Matthias, Inaba, Hiroto, Pui, Ching-Hon, Relling, Mary V, Manabe, Atsushi, Hori, Hiroki, Schmiegelow, Kjeld, Yeoh, Allen E J, Evans, William E, Yang, Jun J
Published in Nature genetics (01.04.2016)
Published in Nature genetics (01.04.2016)
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Identifying IGH disease clones for MRD monitoring in childhood B-cell acute lymphoblastic leukemia using RNA-Seq
Li, Zhenhua, Jiang, Nan, Lim, Evelyn Huizi, Chin, Winnie Hui Ni, Lu, Yi, Chiew, Kean Hui, Kham, Shirley Kow Yin, Yang, Wentao, Quah, Thuan Chong, Lin, Hai Peng, Tan, Ah Moy, Ariffin, Hany, Yang, Jun J., Yeoh, Allen Eng-Juh
Published in Leukemia (01.09.2020)
Published in Leukemia (01.09.2020)
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Minimal Residual Disease–Guided Treatment Deintensification for Children With Acute Lymphoblastic Leukemia: Results From the Malaysia-Singapore Acute Lymphoblastic Leukemia 2003 Study
ENG JUH YEOH, Allen, ARIFFIN, Hany, LEE AI CHONG, AH MOY TAN, HAI PENG LIN, THUAN CHONG QUAH, LI GENG CHAI, Elaine, SZE NGA KWOK, Cecilia, YIONG HUAK CHAN, PONNUDURAI, Kuperan, CAMPANA, Dario, POH LIN TAN, MEI YOKE CHAN, KOW YIN KHAM, Shirley
Published in Journal of clinical oncology (01.07.2012)
Published in Journal of clinical oncology (01.07.2012)
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Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP
Qian, Maoxiang, Zhang, Hui, Kham, Shirley Kow-Yin, Liu, Shuguang, Jiang, Chuang, Zhao, Xujie, Lu, Yi, Goodings, Charnise, Lin, Ting-Nien, Zhang, Ranran, Moriyama, Takaya, Yin, Zhaohong, Li, Zhenhua, Quah, Thuan Chong, Ariffin, Hany, Tan, Ah Moy, Shen, Shuhong, Bhojwani, Deepa, Hu, Shaoyan, Chen, Suning, Zheng, Huyong, Pui, Ching-Hon, Yeoh, Allen Eng-Juh, Yang, Jun J
Published in Genome research (01.02.2017)
Published in Genome research (01.02.2017)
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Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse
Garg, Manoj, Nagata, Yasunobu, Kanojia, Deepika, Mayakonda, Anand, Yoshida, Kenichi, Haridas Keloth, Sreya, Zang, Zhi Jiang, Okuno, Yusuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Ding, Ling-Wen, Alpermann, Tamara, Sun, Qiao-Yang, Lin, De-Chen, Chien, Wenwen, Madan, Vikas, Liu, Li-Zhen, Tan, Kar-Tong, Sampath, Abhishek, Venkatesan, Subhashree, Inokuchi, Koiti, Wakita, Satoshi, Yamaguchi, Hiroki, Chng, Wee Joo, Kham, Shirley-Kow Yin, Yeoh, Allen Eng-Juh, Sanada, Masashi, Schiller, Joanna, Kreuzer, Karl-Anton, Kornblau, Steven M., Kantarjian, Hagop M., Haferlach, Torsten, Lill, Michael, Kuo, Ming-Chung, Shih, Lee-Yung, Blau, Igor-Wolfgang, Blau, Olga, Yang, Henry, Ogawa, Seishi, Koeffler, H. Phillip
Published in Blood (26.11.2015)
Published in Blood (26.11.2015)
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FLT3 mutation and expression did not adversely affect clinical outcome of childhood acute leukaemia-a study of 531 Southeast Asian children by the Ma-Spore study group
Leow, Shuangjie, Kham, Shirley Kow-Yin, Ariffin, Hany, Quah, Thuan Chong, Yeoh, Allen Eng-Juh
Published in Hematological oncology (01.12.2011)
Published in Hematological oncology (01.12.2011)
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Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations
Hu, Shaoyan, Qian, Maoxiang, Zhang, Hui, Guo, Yu, Yang, Jin, Zhao, Xujie, He, Hailong, Lu, Jun, Pan, Jian, Chang, Meimei, Du, Guoqing, Lin, Ting-Nien, Kham, Shirley Kow-Yin, Quah, Thuan Chong, Ariffin, Hany, Tan, Ah-Moy, Cheng, Yong, Li, Chunliang, Yeoh, Allen Eng-Juh, Pui, Ching-Hon, Skanderup, Anders Jacobsen, Yang, Jun J.
Published in Blood (15.06.2017)
Published in Blood (15.06.2017)
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Journal Article
RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia
Koschut, David, Ray, Debleena, Li, Zhenhua, Giarin, Emanuela, Groet, Jürgen, Alić, Ivan, Kham, Shirley Kow-Yin, Chng, Wee Joo, Ariffin, Hany, Weinstock, David M., Yeoh, Allen Eng-Juh, Basso, Giuseppe, Nižetić, Dean
Published in Oncogene (28.01.2021)
Published in Oncogene (28.01.2021)
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Practical Considerations for Using RNA Sequencing in Management of B-Lymphoblastic Leukemia: Malaysia-Singapore Acute Lymphoblastic Leukemia 2020 Implementation Strategy
Ni Chin, Winnie Hui, Li, Zhenhua, Jiang, Nan, Lim, Evelyn Huizi, Suang Lim, Joshua Yew, Lu, Yi, Chiew, Kean Hui, Yin Kham, Shirley Kow, Zhi Oh, Bernice Ling, Tan, Ah Moy, Ariffin, Hany, Yang, Jun J, Eng-Juh Yeoh, Allen
Published in The Journal of molecular diagnostics : JMD (01.10.2021)
Published in The Journal of molecular diagnostics : JMD (01.10.2021)
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Journal Article
RUNX1 point mutations potentially identify a subset of early immature T-cell acute lymphoblastic leukaemia that may originate from differentiated T-cells
Mok, Michelle Meng Huang, Du, Linsen, Wang, Chelsia Qiuxia, Tergaonkar, Vinay, Liu, Te Chih, Yin Kham, Shirley Kow, Sanda, Takaomi, Yeoh, Allen Eng-Juh, Osato, Motomi
Published in Gene (15.07.2014)
Published in Gene (15.07.2014)
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Journal Article
Identification of prognostic protein biomarkers in childhood acute lymphoblastic leukemia (ALL)
Jiang, Nan, Kham, Shirley Kow Yin, Koh, Grace Shimin, Suang Lim, Joshua Yew, Ariffin, Hany, Chew, Fook Tim, Yeoh, Allen Eng Juh
Published in Journal of proteomics (16.05.2011)
Published in Journal of proteomics (16.05.2011)
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Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: Results from the Malaysia-Singapore ALL Study Group
Yeoh, Allen Eng-Juh, Lu, Yi, Chan, Jason Yong-Sheng, Chan, Yiong Huak, Ariffin, Hany, Kham, Shirley Kow-Yin, Quah, Thuan Chong
Published in Leukemia research (01.03.2010)
Published in Leukemia research (01.03.2010)
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Journal Article
Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore
Kham, Shirley Kow Yin, Soh, Chin Kok, Liu, Te Chih, Chan, Yiong Huak, Ariffin, Hany, Tan, Poh Lin, Yeoh, Allen Eng Juh
Published in European journal of clinical pharmacology (01.04.2008)
Published in European journal of clinical pharmacology (01.04.2008)
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Journal Article
Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and transporters using a customized oligonucleotide array
Lu, Yi, Kow-Yin Kham, Shirley, Foo, Toon-Chai, Hany, Ariffin, Quah, Thuan-Chong, Eng-Juh Yeoh, Allen
Published in Analytical biochemistry (2007)
Published in Analytical biochemistry (2007)
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Journal Article
Corrigendum to “Genotyping of eight polymorphic genes encoding drug-metabolizing enzymes and transporters using a customized oligonucleotide array” [Anal. Biochem. 360 (2007) 105–113]
Lu, Yi, Kham, Shirley Kow-Yin, Foo, Toon-Chai, Ariffin, Hany, Quah, Thuan-Chong, Yeoh, Allen Eng-Juh
Published in Analytical biochemistry (01.06.2008)
Published in Analytical biochemistry (01.06.2008)
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Journal Article
Intensifying Treatment of Childhood B-Lymphoblastic Leukemia With IKZF1 Deletion Reduces Relapse and Improves Overall Survival: Results of Malaysia-Singapore ALL 2010 Study
Yeoh, Allen Eng Juh, Lu, Yi, Chin, Winnie Hui Ni, Chiew, Edwynn Kean Hui, Lim, Evelyn Huizi, Li, Zhenhua, Kham, Shirley Kow Yin, Chan, Yiong Huak, Abdullah, Wan Ariffin, Lin, Hai Peng, Chan, Lee Lee, Lam, Joyce Ching Mei, Tan, Poh Lin, Quah, Thuan Chong, Tan, Ah Moy, Ariffin, Hany
Published in Journal of clinical oncology (10.09.2018)
Published in Journal of clinical oncology (10.09.2018)
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Journal Article
Digital PCR for Minimal Residual Disease Quantitation Using Immunoglobulin/T-Cell Receptor Gene Rearrangements in Acute Lymphoblastic Leukemia
Lu, Yi, Li, Zhenhua, Lim, Evelyn Huizi, Huan, Pei Tee, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh
Published in The Journal of molecular diagnostics : JMD (01.06.2022)
Published in The Journal of molecular diagnostics : JMD (01.06.2022)
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Journal Article
Anthracycline-Free Protocol for Favorable-Risk Childhood ALL: A Noninferiority Comparison Between Malaysia-Singapore ALL 2003 and ALL 2010 Studies
Ariffin, Hany, Chiew, Edwynn Kean Hui, Oh, Bernice Ling Zhi, Lee, Shawn Hsien Ren, Lim, Evelyn Huizi, Kham, Shirley Kow Yin, Abdullah, Wan Ariffin, Chan, Lee Lee, Foo, Koon Mian, Lam, Joyce Ching Mei, Chan, Yiong Huak, Lin, Hai Peng, Quah, Thuan Chong, Tan, Ah Moy, Yeoh, Allen Eng Juh
Published in Journal of clinical oncology (10.07.2023)
Published in Journal of clinical oncology (10.07.2023)
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Journal Article
Digital PCR for Minimal Residual Disease Quantitation Using Immunoglobulin/T-Cell Receptor Gene Rearrangements in Acute Lymphoblastic Leukemia: A Proposed Analytic Algorithm
Lu, Yi, Li, Zhenhua, Lim, Evelyn Huizi, Huan, Pei Tee, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh
Published in The Journal of molecular diagnostics : JMD (01.06.2022)
Published in The Journal of molecular diagnostics : JMD (01.06.2022)
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