G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program
Yim, Christina Y, Sekula, David J, Hever-Jardine, Mary P, Liu, Xi, Warzecha, Joshua M, Tam, Janice, Freemantle, Sarah J, Dmitrovsky, Ethan, Spinella, Michael J
Published in Cancer research (Chicago, Ill.) (01.03.2016)
Published in Cancer research (Chicago, Ill.) (01.03.2016)
Get full text
Journal Article
Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine
Albany, Costantine, Hever-Jardine, Mary P, von Herrmann, Katherine M, Yim, Christina Y, Tam, Janice, Warzecha, Joshua M, Shin, Leah, Bock, Sarah E, Curran, Brian S, Chaudhry, Aneeq S, Kim, Fred, Sandusky, George E, Taverna, Pietro, Freemantle, Sarah J, Christensen, Brock C, Einhorn, Lawrence H, Spinella, Michael J
Published in Oncotarget (10.01.2017)
Published in Oncotarget (10.01.2017)
Get full text
Journal Article
MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia
Brown, Fiona C, Still, Eric, Koche, Richard P, Yim, Christina Y, Takao, Sumiko, Cifani, Paolo, Reed, Casie, Gunasekera, Shehana, Ficarro, Scott B, Romanienko, Peter, Mark, Willie, McCarthy, Craig, de Stanchina, Elisa, Gonen, Mithat, Seshan, Venkatraman, Bhola, Patrick, O'Donnell, Conor, Spitzer, Barbara, Stutzke, Crystal, Lavallée, Vincent-Philippe, Hébert, Josée, Krivtsov, Andrei V, Melnick, Ari, Paietta, Elisabeth M, Tallman, Martin S, Letai, Anthony, Sauvageau, Guy, Pouliot, Gayle, Levine, Ross, Marto, Jarrod A, Armstrong, Scott A, Kentsis, Alex
Published in Cancer discovery (01.04.2018)
Published in Cancer discovery (01.04.2018)
Get full text
Journal Article
Mood Disorders and Obesity: Understanding Inflammation as a Pathophysiological Nexus
Soczynska, Joanna K., Kennedy, Sidney H., Woldeyohannes, Hanna O., Liauw, Samantha S., Alsuwaidan, Mohammad, Yim, Christina Y., McIntyre, Roger S.
Published in Neuromolecular medicine (01.06.2011)
Published in Neuromolecular medicine (01.06.2011)
Get full text
Journal Article
1106 Molecular mechanisms of immunogenic cell death driven by PT-112
Guilbaud, Emma, Yamazaki, Takahiro, Congenie, Maria, Yim, Christina, Ames, Tyler, Galluzzi, Lorenzo
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer
Yim, Christina Y, Bikorimana, Emmanuel, Khan, Ema, Warzecha, Joshua M, Shin, Leah, Rodriguez, Jennifer, Dmitrovsky, Ethan, Freemantle, Sarah J, Spinella, Michael J
Published in Cell cycle (Georgetown, Tex.) (01.01.2017)
Published in Cell cycle (Georgetown, Tex.) (01.01.2017)
Get full text
Journal Article
PT-112 Induces Mitochondrial Stress and Immunogenic Cell Death, Targeting Tumor Cells with Mitochondrial Deficiencies
Soler-Agesta, Ruth, Marco-Brualla, Joaquín, Minjárez-Sáenz, Martha, Yim, Christina Y, Martínez-Júlvez, Marta, Price, Matthew R, Moreno-Loshuertos, Raquel, Ames, Tyler D, Jimeno, José, Anel, Alberto
Published in Cancers (01.08.2022)
Published in Cancers (01.08.2022)
Get full text
Journal Article
Mood Disorders and Obesity: Understanding Inflammation as a Pathophysiological Nexus
Soczynska, Joanna K., Kennedy, Sidney H., Woldeyohannes, Hanna O., Liauw, Samantha S., Alsuwaidan, Mohammad, Yim, Christina Y., McIntyre, Roger S.
Published in Neuromolecular medicine (01.06.2011)
Published in Neuromolecular medicine (01.06.2011)
Get full text
Journal Article
1118 Immunologically relevant effects of PT-112 on cancer cell mitochondria
Yamazaki, Takahiro, Galluzzi, Lorenzo, Yim, Christina, Ames, Tyler
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
Get full text
Journal Article
A phase 2 study of immunogenic cell death inducer PT-112 in patients with metastatic castration-resistant prostate cancer
Bryce, Alan Haruo, Karp, Daniel D., Tagawa, Scott T., Nordquist, Luke T., Rathkopf, Dana E., Adra, Nabil, Dorff, Tanya B., Baeck, Johan, O'Donnell, Joseph Francis, Ames, Tyler David, Yim, Christina Y., Price, Matthew, Scher, Howard I.
Published in Journal of clinical oncology (20.02.2023)
Published in Journal of clinical oncology (20.02.2023)
Get full text
Journal Article
A Phase I Dose Escalation Study of PT-112 in Patients with Relapsed or Refractory Multiple Myeloma
Kourelis, Taxiarchis, Ailawadhi, Sikander, Vogl, Dan T., Cooper, Dennis, Ames, Tyler D, Yim, Christina Y, Price, Matthew R, Jimeno, Jose J, Bergsagel, P. Leif
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article
A phase 1b study of novel immunogenic cell death inducer PT-112 plus PD-L1 inhibitor avelumab in metastatic castrate-resistant prostate cancer (mCRPC) patients
Bryce, Alan Haruo, Dronca, Roxana Stefania, Costello, Brian Addis, Aparicio, Ana, Subudhi, Sumit Kumar, O'Donnell, Joseph F., Jimeno, Jose, Yim, Christina Yeaeun, Ames, Tyler David, Price, Matthew, Karp, Daniel D.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Abstract C128: PT-112, a novel immunogenic cell death inducer, causes ribosomal biogenesis inhibition and organelle stress in cancer cells
Yim, Christina Y., Congenie, Maria T., Johnson, Hannah L., Mancini, Maureen G., Stossi, Fabio, Mancini, Michael A., Azofeifa, Joey, Price, Matthew R., Baeck, Johan, Ames, Tyler D.
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
Get full text
Journal Article
Abstract 1115: PT-112 induces potent mitochondrial stress and immunogenic cell death in human prostate cancer cell lines
Soler-Agesta, Ruth, Ames, Tyler D., Price, Matthew, Jimeno, José, Yim, Christina Y., Moreno-Loshuertos, Raquel, Anel, Alberto
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer
Yim, Christina Y., Bikorimana, Emmanuel, Khan, Ema, Warzecha, Joshua M., Shin, Leah, Rodriguez, Jennifer, Dmitrovsky, Ethan, Freemantle, Sarah J., Spinella, Michael J.
Published in Cell Cycle (02.11.2017)
Published in Cell Cycle (02.11.2017)
Get full text
Report