Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes
HONGMEI ZHAO, PRZYBYLSKA, Malgorzata, WU, I-Huan, JINHUA ZHANG, SIEGEL, Craig, KOMARNITSKY, Svetlana, YEW, Nelson S, CHENG, Seng H
Published in Diabetes (New York, N.Y.) (01.05.2007)
Published in Diabetes (New York, N.Y.) (01.05.2007)
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Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine
Leger, Andrew J, Altobelli, Allison, Mosquea, Leocadia M, Belanger, Adam J, Song, Antonius, Cheng, Seng H, Jiang, Canwen, Yew, Nelson S
Published in Journal of bone and mineral metabolism (01.09.2010)
Published in Journal of bone and mineral metabolism (01.09.2010)
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Increased Hepatic Insulin Action in Diet-Induced Obese Mice Following Inhibition of Glucosylceramide Synthase
Yew, Nelson S, Zhao, Hongmei, Hong, Eun-Gyoung, Wu, I-Huan, Przybylska, Malgorzata, Siegel, Craig, Shayman, James A, Arbeeny, Cynthia M, Kim, Jason K, Jiang, Canwen, Cheng, Seng H
Published in PloS one (21.06.2010)
Published in PloS one (21.06.2010)
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Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs
Yew, Nelson S., Zhao, Hongmei, Wu, I-Huan, Song, Antonius, Tousignant, Jennifer D., Przybylska, Malgorzata, Cheng, Seng H.
Published in Molecular therapy (01.03.2000)
Published in Molecular therapy (01.03.2000)
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Contribution of Toll-like Receptor 9 Signaling to the Acute Inflammatory Response to Nonviral Vectors
Zhao, Hongmei, Hemmi, Hiraoki, Akira, Shizuo, Cheng, Seng H, Scheule, Ronald K, Yew, Nelson S
Published in Molecular therapy (01.02.2004)
Published in Molecular therapy (01.02.2004)
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Comparison of Microflow and Analytical Flow Liquid Chromatography Coupled to Mass Spectrometry Global Metabolomics Methods Using a Urea Cycle Disorder Mouse Model
Geller, Sarah, Lieberman, Harvey, Belanger, Adam J, Yew, Nelson S, Kloss, Alla, Ivanov, Alexander R
Published in Journal of proteome research (07.01.2022)
Published in Journal of proteome research (07.01.2022)
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Excretion of excess nitrogen and increased survival by loss of SLC6A19 in a mouse model of ornithine transcarbamylase deficiency
Belanger, Adam J., Gefteas, Estelle, Przybylska, Malgorzata, Geller, Sarah, Anarat‐Cappillino, Gülbenk, Kloss, Alla, Yew, Nelson S.
Published in Journal of inherited metabolic disease (01.01.2023)
Published in Journal of inherited metabolic disease (01.01.2023)
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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
Hyde, Stephen C, Pringle, Ian A, Abdullah, Syahril, Lawton, Anna E, Davies, Lee A, Varathalingam, Anusha, Nunez-Alonso, Graciela, Green, Anne-Marie, Bazzani, Reto P, Sumner-Jones, Stephanie G, Chan, Mario, Li, Hongyu, Yew, Nelson S, Cheng, Seng H, Christopher Boyd, A, Davies, Jane C, Griesenbach, Uta, Porteous, David J, Sheppard, David N, Munkonge, Felix M, Alton, Eric W F W, Gill, Deborah R
Published in Nature biotechnology (01.05.2008)
Published in Nature biotechnology (01.05.2008)
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Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice
Zhao, Hongmei, Przybylska, Malgorzata, Wu, I‐Huan, Zhang, Jinhua, Maniatis, Panagiotis, Pacheco, Joshua, Piepenhagen, Peter, Copeland, Diane, Arbeeny, Cynthia, Shayman, James A., Aerts, Johannes M., Jiang, Canwen, Cheng, Seng H., Yew, Nelson S.
Published in Hepatology (Baltimore, Md.) (01.07.2009)
Published in Hepatology (Baltimore, Md.) (01.07.2009)
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Inhibiting neutral amino acid transport for the treatment of phenylketonuria
Belanger, Adam M, Przybylska, Malgorzata, Gefteas, Estelle, Furgerson, Matthew, Geller, Sarah, Kloss, Alla, Cheng, Seng H, Zhu, Yunxiang, Yew, Nelson S
Published in JCI insight (26.07.2018)
Published in JCI insight (26.07.2018)
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Correction of the nonlinear dose response improves the viability of adenoviral vectors for gene therapy of Fabry disease
Ziegler, Robin J, Li, Chester, Cherry, Maribeth, Zhu, Yunxiang, Hempel, Donna, van Rooijen, Nico, Ioannou, Yiannis A, Desnick, Robert J, Goldberg, Mark A, Yew, Nelson S, Cheng, Seng H
Published in Human gene therapy (20.05.2002)
Published in Human gene therapy (20.05.2002)
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AAV8-mediated expression of N-acetylglucosamine-1-phosphate transferase attenuates bone loss in a mouse model of mucolipidosis II
Ko, Ah-Ra, Jin, Dong-Kyu, Cho, Sung Yoon, Park, Sung Won, Przybylska, Malgorzata, Yew, Nelson S., Cheng, Seng H., Kim, Jung-Sun, Kwak, Min Jung, Kim, Su Jin, Sohn, Young Bae
Published in Molecular genetics and metabolism (01.04.2016)
Published in Molecular genetics and metabolism (01.04.2016)
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Erythrocytes encapsulated with phenylalanine hydroxylase exhibit improved pharmacokinetics and lowered plasma phenylalanine levels in normal mice
Yew, Nelson S., Dufour, Emmanuelle, Przybylska, Malgorzata, Putelat, Julie, Crawley, Cristin, Foster, Meta, Gentry, Sarah, Reczek, David, Kloss, Alla, Meyzaud, Aurélien, Horand, Françoise, Cheng, Seng H., Godfrin, Yann
Published in Molecular genetics and metabolism (01.08.2013)
Published in Molecular genetics and metabolism (01.08.2013)
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Adeno-associated virus-mediated expression of acid sphingomyelinase decreases atherosclerotic lesion formation in apolipoprotein E−/− mice
Leger, Andrew J., Mosquea, Leocadia M., Li, Lingyun, Chuang, WeiLien, Pacheco, Joshua, Taylor, Kristin, Luo, Zhengyu, Piepenhagen, Peter, Ziegler, Robin, Moreland, Rod, Urabe, Akihiro, Jiang, Canwen, Cheng, Seng H., Yew, Nelson S.
Published in The journal of gene medicine (01.06.2011)
Published in The journal of gene medicine (01.06.2011)
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