The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer
López‐Plana, Anna, Fernández‐Nogueira, Patricia, Muñoz‐Guardiola, Pau, Solé‐Sánchez, Sònia, Megías‐Roda, Elisabet, Pérez‐Montoyo, Héctor, Jauregui, Patricia, Yeste‐Velasco, Marc, Gómez‐Ferreria, Mariana, Erazo, Tatiana, Ametller, Elisabet, Recalde‐Percaz, Leire, Moragas‐Garcia, Núria, Noguera‐Castells, Aleix, Mancino, Mario, Morán, Teresa, Nadal, Ernest, Alfón, José, Domènech, Carles, Gascon, Pere, Lizcano, Jose M., Fuster, Gemma, Bragado, Paloma
Published in International journal of cancer (15.08.2020)
Published in International journal of cancer (15.08.2020)
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Journal Article
ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models
Polonio‐Alcalá, Emma, Solé‐Sánchez, Sònia, Muñoz‐Guardiola, Pau, Megías‐Roda, Elisabet, Perez‐Montoyo, Héctor, Yeste‐Velasco, Marc, Alfón, Jose, Lizcano, Jose Miguel, Domènech, Carles, Ruiz‐Martínez, Santiago, Puig, Teresa
Published in Cancer communications (London, England) (01.06.2022)
Published in Cancer communications (London, England) (01.06.2022)
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ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer
Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muñoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana
Published in BMC cancer (22.07.2024)
Published in BMC cancer (22.07.2024)
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Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer
Felip, Isidre, Moiola, Cristian Pablo, Megino-Luque, Cristina, Lopez-Gil, Carlos, Cabrera, Silvia, Solé-Sánchez, Sonia, Muñoz-Guardiola, Pau, Megias-Roda, Elisabet, Pérez-Montoyo, Héctor, Alfon, José, Yeste-Velasco, Marc, Santacana, María, Dolcet, Xavier, Reques, Armando, Oaknin, Ana, Rodríguez-Freixinos, Victor, Lizcano, José Miguel, Domènech, Carles, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Colas, Eva, Eritja, Nuria
Published in Gynecologic oncology (01.05.2019)
Published in Gynecologic oncology (01.05.2019)
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Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer
Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muéoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana
Published in BMC cancer (29.07.2024)
Published in BMC cancer (29.07.2024)
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Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models
Mancini, Andrea, Colapietro, Alessandro, Cristiano, Loredana, Rossetti, Alessandra, Mattei, Vincenzo, Gravina, Giovanni Luca, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Festuccia, Claudio
Published in Frontiers in oncology (02.11.2022)
Published in Frontiers in oncology (02.11.2022)
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Journal Article
Identification of ZDHHC14 as a novel human tumour suppressor gene
Yeste-Velasco, Marc, Mao, Xueying, Grose, Richard, Kudahetti, Sakunthala C, Lin, Dongmei, Marzec, Jacek, Vasiljević, Natasa, Chaplin, Tracy, Xue, Liyan, Xu, Maojia, Foster, Julie M, Karnam, Santi S, James, Sharon Y, Chioni, Athina-Myrto, Gould, David, Lorincz, Attila T, Oliver, R Tim D, Chelala, Claude, Thomas, Gareth M, Shipley, Janet M, Mather, Stephen J, Berney, Daniel M, Young, Bryan D, Lu, Yong-Jie
Published in The Journal of pathology (01.04.2014)
Published in The Journal of pathology (01.04.2014)
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Journal Article
The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers
Noel, Elodie E, Yeste-Velasco, Marc, Mao, Xueying, Perry, Jackie, Kudahetti, Sakunthala C, Li, Ningfeng F, Sharp, Swee, Chaplin, Tracy, Xue, Liyan, McIntyre, Alan, Shan, Ling, Powles, Thomas, Oliver, R. Tim D, Young, Bryan D, Shipley, Janet, Berney, Daniel M, Joel, Simon P, Lu, Yong-Jie
Published in The American journal of pathology (01.06.2010)
Published in The American journal of pathology (01.06.2010)
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Journal Article
Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer
Stankiewicz, Elzbieta, Mao, Xueying, Mangham, D. Chas, Xu, Lei, Yeste-Velasco, Marc, Fisher, Gabrielle, North, Bernard, Chaplin, Tracy, Young, Bryan, Wang, Yuqin, Kaur Bansal, Jasmin, Kudahetti, Sakunthala, Spencer, Lucy, Foster, Christopher S., Møller, Henrik, Scardino, Peter, Oliver, R. Tim, Shamash, Jonathan, Cuzick, Jack, Cooper, Colin S., Berney, Daniel M., Lu, Yong-Jie
Published in Scientific reports (11.07.2017)
Published in Scientific reports (11.07.2017)
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The antiproliferative activity of melatonin in B65 rat dopaminergic neuroblastoma cells is related to the downregulation of cell cycle-related genes
Pizarro, Javier G., Yeste-Velasco, Marc, Esparza, José Luis, Verdaguer, Ester, Pallàs, Mercè, Camins, Antoni, Folch, Jaume
Published in Journal of pineal research (01.08.2008)
Published in Journal of pineal research (01.08.2008)
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Journal Article
Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the Atm/p53/E2F-1 path in cerebellar granule neurons
Alvira, Daniel, Yeste-Velasco, Marc, Folch, Jaume, Casadesús, Gemma, Smith, Mark A., Pallàs, Mercè, Camins, Antoni
Published in Journal of neuroscience research (01.11.2007)
Published in Journal of neuroscience research (01.11.2007)
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Journal Article
Neuroprotective effects of SB‐415286 on hydrogen peroxide‐induced cell death in B65 rat neuroblastoma cells and neurons
Pizarro, Javier G., Yeste‐Velasco, Marc, Rimbau, Victor, Casadesús, Gemma, Smith, Mark A., Pallàs, Mercè, Folch, Jaume, Camins, Antoni
Published in International journal of developmental neuroscience (01.05.2008)
Published in International journal of developmental neuroscience (01.05.2008)
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암의 치료를 위한 약제학적 조합
YESTE VELASCO MARC, PEREZ MONTOYO HECTOR, ALFON CORIAT JOSE ALBERTO, YOLDI SALINAS GUILLERMO, MUNOZ GUARDIOLA PAU, LIZCANO DE LA VEGA JOSE MIGUEL, FESTUCCIA CLAUDIO, DOMENECH GARCIA CARLES, PARIS CODERCH LAIA, SEGURA GUINARD MIGUEL FRANCISCO
Year of Publication 18.10.2022
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Year of Publication 18.10.2022
Patent
Protein S-palmitoylation and cancer
Yeste-Velasco, Marc, Linder, Maurine E., Lu, Yong-Jie
Published in Biochimica et biophysica acta (01.08.2015)
Published in Biochimica et biophysica acta (01.08.2015)
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Journal Article
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells
Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M
Published in Autophagy (03.06.2021)
Published in Autophagy (03.06.2021)
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Journal Article
Abstract 1805: ABTL0812, a Phase 2 clinical stage pro-autophagy anticancer drug exhibits immunomodulatory effects that modify tumor microenvironment in pancreatic cancer models
Yoldi, Guillermo, Munoz-Guardiola, Pau, Megias, Elisabet, Perez-Montoyo, Hector, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Lizcano, Jose Miguel
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Phase 2 clinical trial of the proautophagic drug ABTL0812 combined with paclitaxel and carboplatin in first-line patients with advanced squamous non-small cell lung carcinoma
Bosch-Barrera, Joaquim, Moran, Teresa, Estévez-García, Purificación, Martín-Martorell, Paloma, Sabatier, Renaud, Nadal, Ernest, Lizcano, Jose M., Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domenech, Carles, Alfon, Jose Alberto
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Correction: ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancer : Alexandra Leary
Leary, Alexandra, Estévez-García, Purificación, Sabatier, Renaud, Ray-Coquard, Isabelle, Romeo, Margarita, Barretina-Ginesta, Pilar, Gil-Martin, Marta, Garralda, Elena, Bosch-Barrera, Joaquim, Morán, Teresa, Martin-Martorell, Paloma, Nadal, Ernest, Gascón, Pere, Rodon, Jordi, Lizcano, Jose M, Muñoz-Guardiola, Pau, Fierro-Durán, Gemma, Pedrós-Gámez, Oriol, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Cortal, Marc, Pérez-Campos, Antonio, Alfon, Jose, Domenech, Carles, Pérez-Fidalgo, Alejandro, Oaknin, Ana
Published in BMC cancer (29.07.2024)
Published in BMC cancer (29.07.2024)
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A first-in-human phase I/Ib dose-escalation clinical trial of the autophagy inducer ABTL0812 in patients with advanced solid tumours
Vidal, Laura, Victoria, Ivan, Gaba, Lydia, Martín, Marta Gil, Brunet, Mercè, Colom, Helena, Cortal, Marc, Gómez-Ferrería, Mariana, Yeste-Velasco, Marc, Perez, Antonio, Rodon, Jordi, Sohal, Davendra P.S., Lizcano, José Miguel, Domènech, Carles, Alfón, José, Gascón, Pere
Published in European journal of cancer (1990) (01.03.2021)
Published in European journal of cancer (1990) (01.03.2021)
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