An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism
Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Román-Fernández, Álvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura C. A., Freckmann, Eva C., McGarry, Lynn, Morton, Jennifer P., Shanks, Emma, Leung, Hing Y., Markert, Elke, Ismail, Shehab, Zanivan, Sara, Blyth, Karen, Bryant, David M.
Published in Nature communications (12.03.2021)
Published in Nature communications (12.03.2021)
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Journal Article
ARL3 activation requires the co-GEF BART and effector-mediated turnover
ElMaghloob, Yasmin, Sot, Begoña, McIlwraith, Michael J, Garcia, Esther, Yelland, Tamas, Ismail, Shehab
Published in eLife (13.01.2021)
Published in eLife (13.01.2021)
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Journal Article
VEGFA, B, C: Implications of the C-Terminal Sequence Variations for the Interaction with Neuropilins
Eldrid, Charles, Zloh, Mire, Fotinou, Constantina, Yelland, Tamas, Yu, Lefan, Mota, Filipa, Selwood, David L, Djordjevic, Snezana
Published in Biomolecules (Basel, Switzerland) (26.02.2022)
Published in Biomolecules (Basel, Switzerland) (26.02.2022)
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Journal Article
Structure of a C. perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
Yelland, Tamas S., Naylor, Claire E., Bagoban, Tannya, Savva, Christos G., Moss, David S., McClane, Bruce A., Blasig, Ingolf E., Popoff, M., Basak, Ajit K.
Published in Journal of molecular biology (09.09.2014)
Published in Journal of molecular biology (09.09.2014)
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Journal Article
The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms
Yelland, Tamas, Garcia, Esther, Samarakoon, Youhani, Ismail, Shehab
Published in Biochemistry (Easton) (29.06.2021)
Published in Biochemistry (Easton) (29.06.2021)
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Journal Article
Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1
Yelland, Tamas, Le, Anh Hoang, Nikolaou, Savvas, Insall, Robert, Machesky, Laura, Ismail, Shehab
Published in Structure (London) (04.03.2021)
Published in Structure (London) (04.03.2021)
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Journal Article
Detailed characterization of the O-linked glycosylation of the neuropilin-1 c/MAM-domain
Windwarder, Markus, Yelland, Tamas, Djordjevic, Snezana, Altmann, Friedrich
Published in Glycoconjugate journal (01.06.2016)
Published in Glycoconjugate journal (01.06.2016)
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Journal Article
Targeting Pf CLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment
Brettell, Skye B, Janha, Omar, Begen, Abbey, Cann, Gillian, Sharma, Saumya, Olaniyan, Niniola, Yelland, Tamas, Hole, Alison J, Alam, Benazir, Mayville, Emily, Gillespie, Ross, Capper, Michael, Fidock, David A, Milligan, Graeme, Clarke, David J, Tobin, Andrew B, Jamieson, Andrew G
Published in Journal of medicinal chemistry (14.11.2024)
Published in Journal of medicinal chemistry (14.11.2024)
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Journal Article
Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment
Brettell, Skye B., Janha, Omar, Begen, Abbey, Cann, Gillian, Sharma, Saumya, Olaniyan, Niniola, Yelland, Tamas, Hole, Alison J., Alam, Benazir, Mayville, Emily, Gillespie, Ross, Capper, Michael, Fidock, David A., Milligan, Graeme, Clarke, David J., Tobin, Andrew B., Jamieson, Andrew G.
Published in Journal of medicinal chemistry (14.11.2024)
Published in Journal of medicinal chemistry (14.11.2024)
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Journal Article
Small Molecule Neuropilin‑1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T‑Cells
Powell, Jonathan, Mota, Filipa, Steadman, David, Soudy, Christelle, Miyauchi, Jeremy T, Crosby, Stuart, Jarvis, Ashley, Reisinger, Tifelle, Winfield, Natalie, Evans, Graham, Finniear, Aled, Yelland, Tamas, Chou, Yi-Tai, Chan, A.W. Edith, O’Leary, Andrew, Cheng, Lili, Liu, Dan, Fotinou, Constantina, Milagre, Carla, Martin, John F, Jia, Haiyan, Frankel, Paul, Djordjevic, Snezana, Tsirka, Stella E, Zachary, Ian C, Selwood, David L
Published in Journal of medicinal chemistry (10.05.2018)
Published in Journal of medicinal chemistry (10.05.2018)
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Journal Article
Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling
Yelland, Tamas, Garcia, Esther, Parry, Charles, Kowalczyk, Dominika, Wojnowska, Marta, Gohlke, Andrea, Zalar, Matja, Cameron, Kenneth, Goodwin, Gillian, Yu, Qing, Zhu, Peng-Cheng, ElMaghloob, Yasmin, Pugliese, Angelo, Archibald, Lewis, Jamieson, Andrew, Chen, Yong Xiang, McArthur, Duncan, Bower, Justin, Ismail, Shehab
Published in Journal of medicinal chemistry (10.02.2022)
Published in Journal of medicinal chemistry (10.02.2022)
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Journal Article
Architecture and hydration of the arginine‐binding site of neuropilin‐1
Mota, Filipa, Fotinou, Constantina, Rana, Rohini R., Chan, A. W. Edith, Yelland, Tamas, Arooz, Mohamed T., O'Leary, Andrew P., Hutton, Jennie, Frankel, Paul, Zachary, Ian, Selwood, David, Djordjevic, Snezana
Published in The FEBS journal (01.04.2018)
Published in The FEBS journal (01.04.2018)
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Journal Article
Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin‐1
Mota, Filipa, Yelland, Tamas, Hutton, Jennie A., Parker, Jennifer, Patsiarika, Anastasia, Chan, A. W. Edith, O'Leary, Andrew, Fotinou, Constantina, Martin, John F., Zachary, Ian C., Djordjevic, Snezana, Frankel, Paul, Selwood, David L.
Published in Chembiochem : a European journal of chemical biology (05.01.2022)
Published in Chembiochem : a European journal of chemical biology (05.01.2022)
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Journal Article
Structural studies of neuropilin‐2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket
Tsai, Yi‐Chun Isabella, Fotinou, Constantina, Rana, Rohini, Yelland, Tamas, Frankel, Paul, Zachary, Ian, Djordjevic, Snezana
Published in The FEBS journal (01.05.2016)
Published in The FEBS journal (01.05.2016)
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Journal Article
Spatial enrichment of phosphoinositide metabolism is a molecular switch to promote metastasis
Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Román-Fernández, Álvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura, Mcgarry, Lynn, Morton, Jennifer P, Shanks, Emma, Leung, Hing, Zanivan, Sara, Ismail, Shehab, Markert, Elke, Blyth, Karen, Bryant, David M
Published in bioRxiv (22.09.2020)
Published in bioRxiv (22.09.2020)
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