Discovery of GBT440, an Orally Bioavailable R‑State Stabilizer of Sickle Cell Hemoglobin
Metcalf, Brian, Chuang, Chihyuan, Dufu, Kobina, Patel, Mira P, Silva-Garcia, Abel, Johnson, Carl, Lu, Qing, Partridge, James R, Patskovska, Larysa, Patskovsky, Yury, Almo, Steven C, Jacobson, Matthew P, Hua, Lan, Xu, Qing, Gwaltney, Stephen L, Yee, Calvin, Harris, Jason, Morgan, Bradley P, James, Joyce, Xu, Donghong, Hutchaleelaha, Athiwat, Paulvannan, Kumar, Oksenberg, Donna, Li, Zhe
Published in ACS medicinal chemistry letters (09.03.2017)
Published in ACS medicinal chemistry letters (09.03.2017)
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Journal Article
Respiratory Syncytial Virus Prevention: A New Era of Vaccines
Lee, Calvin Yee Fen, Khan, Salman J, Vishal, Fnu, Alam, Sadaf, Murtaza, Syeda Fatima
Published in Curēus (Palo Alto, CA) (11.09.2023)
Published in Curēus (Palo Alto, CA) (11.09.2023)
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Journal Article
Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors
Dementiev, Alexey, Silva, Abel, Yee, Calvin, Li, Zhe, Flavin, Michael T., Sham, Hing, Partridge, James R.
Published in Blood advances (13.03.2018)
Published in Blood advances (13.03.2018)
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Journal Article
Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors
Jaime-Figueroa, Saul, De Vicente, Javier, Hermann, Johannes, Jahangir, Alam, Jin, Sue, Kuglstatter, Andreas, Lynch, Stephen M., Menke, John, Niu, Linghao, Patel, Vaishali, Shao, Ada, Soth, Michael, Vu, Minh Diem, Yee, Calvin
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Journal Article
Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors
Yang, Hanbiao, Hendricks, Robert T., Arora, Nidhi, Nitzan, Dov, Yee, Calvin, Lucas, Matthew C., Yang, Yanli, Fung, Amy, Rajyaguru, Sonal, Harris, Seth F., Leveque, Vincent J.P., Hang, Julie Q., Pogam, Sophie Le, Reuter, Deborah, Tavares, Gisele A.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Alpha-1-Antitrypsin and a Broad Spectrum Metalloprotease Inhibitor, RS113456, Have Similar Acute Anti-Inflammatory Effects
Churg, Andrew, Dai, Jin, Zay, Katalin, Karsan, Aly, Hendricks, Richard, Yee, Calvin, Martin, Robert, MacKenzie, Rebecca, Xie, Changshi, Zhang, Li, Shapiro, Stephen, Wright, Joanne L
Published in Laboratory investigation (01.08.2001)
Published in Laboratory investigation (01.08.2001)
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Journal Article
Mutations in the B2 Bradykinin Receptor Reveal a Different Pattern of Contacts for Peptidic Agonists and Peptidic Antagonists
Jarnagin, Kurt, Bhakta, Sunil, Zuppan, Patty, Yee, Calvin, Ho, Teresa, Phan, Thu, Tahilramani, Ram, Pease, JoeH.B., Miller, Aaron, Freedman, Richard
Published in The Journal of biological chemistry (08.11.1996)
Published in The Journal of biological chemistry (08.11.1996)
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Journal Article
Conversion of cassava leaf to bioavailable, high‐protein yeast cell biomass
Boundy‐Mills, Kyria, Karuna, Nardrapee, Garay, L Antonio, Lopez, Julian M, Yee, Calvin, Hitomi, Alex, Nishi, Audry K, Enriquez, Lauren L, Roberts, Christopher, Block, David E, Jeoh, Tina
Published in Journal of the science of food and agriculture (01.04.2019)
Published in Journal of the science of food and agriculture (01.04.2019)
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Journal Article
페로포르틴 억제제로서의 시클로알킬 피리미딘
YEE CALVIN WESLEY, LI ZHE, RADEMACHER PETER MICHAEL, XU QING, ALT CARSTEN, NILAR SHAHUL
Year of Publication 12.01.2023
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Year of Publication 12.01.2023
Patent
3‑Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models
Soth, Michael, Hermann, Johannes C, Yee, Calvin, Alam, Muzaffar, Barnett, Jim W, Berry, Pamela, Browner, Michelle F, Frank, Karl, Frauchiger, Sandra, Harris, Seth, He, Yang, Hekmat-Nejad, Mohammad, Hendricks, Than, Henningsen, Robert, Hilgenkamp, Ramona, Ho, Hoangdung, Hoffman, Ann, Hsu, Pei-Yuan, Hu, Dong-Qing, Itano, Andrea, Jaime-Figueroa, Saul, Jahangir, Alam, Jin, Sue, Kuglstatter, Andreas, Kutach, Alan K, Liao, Cheng, Lynch, Stephen, Menke, John, Niu, Linghao, Patel, Vaishali, Railkar, Aruna, Roy, Douglas, Shao, Ada, Shaw, David, Steiner, Sandra, Sun, Yongliang, Tan, Seng-Lai, Wang, Sandra, Vu, Minh Diem
Published in Journal of medicinal chemistry (10.01.2013)
Published in Journal of medicinal chemistry (10.01.2013)
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Journal Article
Isolation of a cDNA encoding a human rolipram-sensitive cyclic AMP phosphodiesterase (PDE IV D)
Baecker, Preston A., Obernolte, Rena, Bach, Chinh, Yee, Calvin, Shelton, Earl R.
Published in Gene (28.01.1994)
Published in Gene (28.01.1994)
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Journal Article
Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome
Lynch, Stephen M., DeVicente, Javier, Hermann, Johannes C., Jaime-Figueroa, Saul, Jin, Sue, Kuglstatter, Andreas, Li, Hongju, Lovey, Allen, Menke, John, Niu, Linghao, Patel, Vaishali, Roy, Douglas, Soth, Michael, Steiner, Sandra, Tivitmahaisoon, Parcharee, Vu, Minh Diem, Yee, Calvin
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Journal Article
Using Ovality to Predict Nonmutagenic, Orally Efficacious Pyridazine Amides as Cell Specific Spleen Tyrosine Kinase Inhibitors
Lucas, Matthew C, Bhagirath, Niala, Chiao, Eric, Goldstein, David M, Hermann, Johannes C, Hsu, Pei-Yuan, Kirchner, Stephan, Kennedy-Smith, Joshua J, Kuglstatter, Andreas, Lukacs, Christine, Menke, John, Niu, Linghao, Padilla, Fernando, Peng, Ying, Polonchuk, Liudmila, Railkar, Aruna, Slade, Michelle, Soth, Michael, Xu, Daigen, Yadava, Preeti, Yee, Calvin, Zhou, Mingyan, Liao, Cheng
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure–activity relationships of benzothiazine-substituted quinolinediones
de Vicente, Javier, Hendricks, Robert T., Smith, David B., Fell, Jay B., Fischer, John, Spencer, Stacey R., Stengel, Peter J., Mohr, Peter, Robinson, John E., Blake, James F., Hilgenkamp, Ramona K., Yee, Calvin, Adjabeng, George, Elworthy, Todd R., Tracy, Jahari, Chin, Elbert, Li, Jim, Wang, Beihan, Bamberg, Joe T., Stephenson, Rebecca, Oshiro, Connie, Harris, Seth F., Ghate, Manjiri, Leveque, Vincent, Najera, Isabel, Pogam, Sophie Le, Rajyaguru, Sonal, Ao-Ieong, Gloria, Alexandrova, Ludmila, Larrabee, Susan, Brandl, Michael, Briggs, Andrew, Sukhtankar, Sunil, Farrell, Robert, Xu, Brian
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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Journal Article
Transport of levovirin prodrugs in the human intestinal Caco-2 cell line
Li, Fujun, Hong, Lei, Mau, Cheng-I, Chan, Rebecca, Hendricks, Than, Dvorak, Chuck, Yee, Calvin, Harris, Jason, Alfredson, Tom
Published in Journal of pharmaceutical sciences (01.06.2006)
Published in Journal of pharmaceutical sciences (01.06.2006)
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Journal Article
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: Structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides
de Vicente, Javier, Hendricks, Robert T., Smith, David B., Fell, Jay B., Fischer, John, Spencer, Stacey R., Stengel, Peter J., Mohr, Peter, Robinson, John E., Blake, James F., Hilgenkamp, Ramona K., Yee, Calvin, Adjabeng, George, Elworthy, Todd R., Li, Jim, Wang, Beihan, Bamberg, Joe T., Harris, Seth F., Wong, April, Leveque, Vincent J.P., Najera, Isabel, Pogam, Sophie Le, Rajyaguru, Sonal, Ao-Ieong, Gloria, Alexandrova, Ludmila, Larrabee, Susan, Brandl, Michael, Briggs, Andrew, Sukhtankar, Sunil, Farrell, Robert
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Journal Article