A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee
Deshmukh, V., Hu, H., Barroga, C., Bossard, C., KC, S., Dellamary, L., Stewart, J., Chiu, K., Ibanez, M., Pedraza, M., Seo, T., Do, L., Cho, S., Cahiwat, J., Tam, B., Tambiah, J.R.S., Hood, J., Lane, N.E., Yazici, Y.
Published in Osteoarthritis and cartilage (01.01.2018)
Published in Osteoarthritis and cartilage (01.01.2018)
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Journal Article
A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study
Yazici, Y., McAlindon, T.E., Fleischmann, R., Gibofsky, A., Lane, N.E., Kivitz, A.J., Skrepnik, N., Armas, E., Swearingen, C.J., DiFrancesco, A., Tambiah, J.R.S., Hood, J., Hochberg, M.C.
Published in Osteoarthritis and cartilage (01.10.2017)
Published in Osteoarthritis and cartilage (01.10.2017)
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Modulation of the Wnt pathway through inhibition of CLK2 and DYRK1A by lorecivivint as a novel, potentially disease-modifying approach for knee osteoarthritis treatment
Deshmukh, V., O'Green, A.L., Bossard, C., Seo, T., Lamangan, L., Ibanez, M., Ghias, A., Lai, C., Do, L., Cho, S., Cahiwat, J., Chiu, K., Pedraza, M., Anderson, S., Harris, R., Dellamary, L., KC, S., Barroga, C., Melchior, B., Tam, B., Kennedy, S., Tambiah, J., Hood, J., Yazici, Y.
Published in Osteoarthritis and cartilage (01.09.2019)
Published in Osteoarthritis and cartilage (01.09.2019)
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A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis
Yazici, Y., McAlindon, T.E., Gibofsky, A., Lane, N.E., Lattermann, C., Skrepnik, N., Swearingen, C.J., Simsek, I., Ghandehari, H., DiFrancesco, A., Gibbs, J., Tambiah, J.R.S., Hochberg, M.C.
Published in Osteoarthritis and cartilage (01.05.2021)
Published in Osteoarthritis and cartilage (01.05.2021)
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Journal Article
THU0046 Small molecule inhibitor of the wnt pathway (SM04755) as a potential topical treatment for psoriasis
Deshmukh, V., Pedraza, M., Lamangan, L., Yazici, Y.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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AB0440 Ethnic minorities experience infrequent biologic switch despite active rheumatoid arthritis disease
Kerr, G., Swearingen, C., Hochberg, S., Ude, J., Yazici, Y.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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POS0828 CONSISTENT EFFICACY WITH APREMILAST IN MEN AND WOMEN TO TREAT ORAL ULCERS ASSOCIATED WITH BEHÇET’S SYNDROME: PHASE 3 RELIEF STUDY RESULTS
Hatemi, G., Mahr, A., Takeno, M., Kim, D., Melikoglu, M., Cheng, S., Richter, S., Jardon, S., Paris, M., Chen, M., Yazici, Y.
Published in Annals of the rheumatic diseases (01.06.2021)
Published in Annals of the rheumatic diseases (01.06.2021)
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An index of only patient-reported outcome measures, routine assessment of patient index data 3 (RAPID3), in two abatacept clinical trials: similar results to disease activity score (DAS28) and other RAPID indices that include physician-reported measures
Pincus, T., Bergman, M. J., Yazici, Y., Hines, P., Raghupathi, K., Maclean, R.
Published in Rheumatology (Oxford, England) (01.03.2008)
Published in Rheumatology (Oxford, England) (01.03.2008)
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SAT0586 Results from a 52 week randomised, double-blind, placebo-controlled, phase 2 study of a novel, wnt pathway inhibitor (SM04690) for knee osteoarthritis treatment
Yazici, Y., McAlindon, T., Gibofsky, A., Lane, N., Clauw, D., Swearingen, C., DiFrancesco, A., Tambiah, J., Hochberg, M.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST–RA database
Sokka, T, Kautiainen, H, Pincus, T, Toloza, S, da Rocha Castelar Pinheiro, G, Lazovskis, J, Hetland, M L, Peets, T, Immonen, K, Maillefert, J F, Drosos, A A, Alten, R, Pohl, C, Rojkovich, B, Bresnihan, B, Minnock, P, Cazzato, M, Bombardieri, S, Rexhepi, S, Rexhepi, M, Andersone, D, Stropuviene, S, Huisman, M, Sierakowski, S, Karateev, D, Skakic, V, Naranjo, A, Baecklund, E, Henrohn, D, Gogus, F, Badsha, H, Mofti, A, Taylor, P, McClinton, C, Yazici, Y
Published in Annals of the rheumatic diseases (01.11.2009)
Published in Annals of the rheumatic diseases (01.11.2009)
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OMERACT-OARSI ‘strict responders’ analysis from results of a randomized, double-blind, placebo-controlled phase 1 study of a novel, intra-articular, injectable, Wnt inhibitor (SM04690) in the treatment of osteoarthritis of the knee
Yazici, Y, Tambiah, J, Swearingen, C.J, DiFrancesco, A, Strand, V
Published in Osteoarthritis and cartilage (01.04.2016)
Published in Osteoarthritis and cartilage (01.04.2016)
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