Case Study: An Evaluation of the Human Relevance of the Synthetic Pyrethroid Metofluthrin-Induced Liver Tumors in Rats Based on Mode of Action
Yamada, Tomoya, Uwagawa, Satoshi, Okuno, Yasuyoshi, Cohen, Samuel M., Kaneko, Hideo
Published in Toxicological sciences (01.03.2009)
Published in Toxicological sciences (01.03.2009)
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Journal Article
Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation
Deguchi, Yoshihito, Yamada, Tomoya, Hirose, Yukihiro, Nagahori, Hirohisa, Kushida, Masahiko, Sumida, Kayo, Sukata, Tokuo, Tomigahara, Yoshitaka, Nishioka, Kazuhiko, Uwagawa, Satoshi, Kawamura, Satoshi, Okuno, Yasuyoshi
Published in Toxicological sciences (01.03.2009)
Published in Toxicological sciences (01.03.2009)
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Journal Article
Comparison of the effects of the synthetic pyrethroid Metofluthrin and phenobarbital on CYP2B form induction and replicative DNA synthesis in cultured rat and human hepatocytes
Hirose, Yukihiro, Nagahori, Hirohisa, Yamada, Tomoya, Deguchi, Yoshihito, Tomigahara, Yoshitaka, Nishioka, Kazuhiko, Uwagawa, Satoshi, Kawamura, Satoshi, Isobe, Naohiko, Lake, Brian G, Okuno, Yasuyoshi
Published in Toxicology (Amsterdam) (05.04.2009)
Published in Toxicology (Amsterdam) (05.04.2009)
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Journal Article
Species differences in the developmental toxicity of procymidone: Remarkable variation in pharmacokinetics, metabolism, and excretion
Tomigahara, Yoshitaka, Tarui, Hirokazu, Nagahori, Hirohisa, Sugimoto, Kenji, Mogi, Masayuki, Nishioka, Kazuhiko, Kawamura, Satoshi, Isobe, Naohiko, Okuno, Yasuyoshi, Kaneko, Hideo
Published in Journal of Pesticide Science (01.01.2015)
Published in Journal of Pesticide Science (01.01.2015)
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Journal Article
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: Possible mechanisms
Kushida, Masahiko, Sukata, Tokuo, Uwagawa, Satoshi, Ozaki, Keisuke, Kinoshita, Anna, Wanibuchi, Hideki, Morimura, Keiichirou, Okuno, Yasuyoshi, Fukushima, Shoji
Published in Toxicology and applied pharmacology (01.11.2005)
Published in Toxicology and applied pharmacology (01.11.2005)
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Journal Article
Functional genomics may allow accurate categorization of the benzimidazole fungicide benomyl: lack of ability to act via steroid-receptor-mediated mechanisms
Yamada, Tomoya, Sumida, Kayo, Saito, Koichi, Ueda, Shinji, Yabushita, Setsuko, Sukata, Tokuo, Kawamura, Satoshi, Okuno, Yasuyoshi, Seki, Takaki
Published in Toxicology and applied pharmacology (15.05.2005)
Published in Toxicology and applied pharmacology (15.05.2005)
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α2-Macroglobulin: A novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers
SUKATA, Tokuo, UWAGAWA, Satoshi, MIKAMI, Nobuyoshi, FUKUSHIMA, Shoji, OZAKI, Keisuke, SUMIDA, Kayo, KIKUCHI, Kaoru, KUSHIDA, Masahiko, SAITO, Koichi, MORIMURA, Keiichirou, OEDA, T. Kenji, OKUNO, Yasuyoshi
Published in The American journal of pathology (01.11.2004)
Published in The American journal of pathology (01.11.2004)
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Journal Article
EFFECTS OF PERINATAL EXPOSURE TO FLUTAMIDE ON SEX HORMONES AND ANDROGEN-DEPENDENT ORGANS IN F1 MALE RATS
MIYATA, Kaori, YABUSHITA, Setsuko, SUKATA, Tokuo, SANO, Masashi, YOSHINO, Hiroko, NAKANISHI, Takumi, OKUNO, Yasuyoshi, MATSUO, Masatoshi
Published in Journal of toxicological sciences (2002)
Published in Journal of toxicological sciences (2002)
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Journal Article
Detailed low‐dose study of 1,1‐b™IS(p‐chlorophenyl)‐2,2,2‐ trichloroethane carcinogenesis suggests the possibility of a hormetic effect
Sukata, Tokuo, Uwagawa, Satoshi, Ozaki, Keisuke, Ogawa, Motome, Nishikawa, Takayuki, Iwai, Syuji, Kinoshita, Anna, Wanibuchi, Hideki, Imaoka, Susumu, Funae, Yoshihiko, Okuno, Yasuyoshi, Fukushima, Shoji
Published in International journal of cancer (01.05.2002)
Published in International journal of cancer (01.05.2002)
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Journal Article
Lack of (Anti-) Androgenic or Estrogenic Effects of Three Pyrethroids (Esfenvalerate, Fenvalerate, and Permethrin) in the Hershberger and Uterotrophic Assays
Kunimatsu, Takeshi, Yamada, Tomoya, Ose, Keiko, Sunami, Osamu, Kamita, Yusuke, Okuno, Yasuyoshi, Seki, Takaki, Nakatsuka, Iwao
Published in Regulatory toxicology and pharmacology (01.04.2002)
Published in Regulatory toxicology and pharmacology (01.04.2002)
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Journal Article
Dissection and weighing of accessory sex glands after formalin fixation, and a 5-day assay using young mature rats are reliable and feasible in the Hershberger assay
Yamada, Tomoya, Sunami, Osamu, Kunimatsu, Takeshi, Kamita, Yusuke, Okuno, Yasuyoshi, Seki, Takaki, Nakatsuka, Iwao, Matsuo, Masatoshi
Published in Toxicology (Amsterdam) (11.05.2001)
Published in Toxicology (Amsterdam) (11.05.2001)
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EVALUATION OF A 5-DAY HERSHBERGER ASSAY USING YOUNG MATURE MALE RATS : METHYLTESTOSTERONE AND p, p'-DDE, BUT NOT FENITROTHION, EXHIBITED ANDROGENIC OR ANTIANDROGENIC ACTIVITY IN VIVO
SUNAMI, Osamu, KUNIMATSU, Takeshi, YAMADA, Tomoya, YABUSHITA, Setsuko, SUKATA, Tokuo, MIYATA, Kaori, KAMITA, Yusuke, OKUNO, Yasuyoshi, SEKI, Takaki, NAKATSUKA, Iwao, MATSUO, Masatoshi
Published in Journal of toxicological sciences (2000)
Published in Journal of toxicological sciences (2000)
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Journal Article
Prenatal Exposure to Flutamide Induces Increased Keratinocyte Growth Factor mRNA, Irreversible Alteration of the Ductal Architecture, but No Change in Receptor Binding Capacity in the Rat Prostate Later in Life
Miyata, Kaori, Yabushita, Setsuko, Okuno, Yasuyoshi, Matsuo, Masatoshi
Published in Journal of Toxicologic Pathology (2003)
Published in Journal of Toxicologic Pathology (2003)
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Journal Article
Lack of changes in brain muscarinic receptor and motor activity of mice after neonatal inhalation exposure to d-allethrin
Tsuji, Ryozo, Kobayashi, Kumiko, Ikeda, Maya, Yoshioka, Takafumi, Yamada, Tomoya, Seki, Takaki, Okuno, Yasuyoshi, Nakatsuka, Iwao, Tsuruo, Yoshihiro, Kishioka, Shiroh
Published in Journal of applied toxicology (01.11.2002)
Published in Journal of applied toxicology (01.11.2002)
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Journal Article
Lack of Enhanced Epithelial Cell Proliferation in the Urinary Bladder of Heterozygous p53 Knockout Mice Given Sodium Ortho-phenylphenate or Uracil
Uwagawa, Satoshi, Ozaki, Keisuke, Sukata, Tokuo, Kushida, Masahiko, Okuno, Yasuyoshi, Fukushima, Shoji
Published in Journal of Toxicologic Pathology (2003)
Published in Journal of Toxicologic Pathology (2003)
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