Hepatocyte Nuclear Factor 4-Mediated Activation of Rat CYP3A1 Gene and Its Modes of Modulation by Apolipoprotein AI Regulatory Protein I and v-ErbA-Related Protein 3
Ogino, Makoto, Nagata, Kiyoshi, Miyata, Masaaki, Yamazoe, Yasushi
Published in Archives of biochemistry and biophysics (01.02.1999)
Published in Archives of biochemistry and biophysics (01.02.1999)
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Prediction of drug-drug interactions for AUCoral of high clearance drug from in vitro data: utilization of a microtiter plate assay and a dispersion model
Yamamoto, Takahito, Suzuki, Akio, Kohno, Yoshiro, Nagata, Kiyoshi, Yamazoe, Yasushi
Published in Current drug metabolism (01.02.2006)
Published in Current drug metabolism (01.02.2006)
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Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator
Watanabe, Keisuke, Sakurai, Kaori, Tsuchiya, Yuri, Yamazoe, Yasushi, Yoshinari, Kouichi
Published in Biochemical pharmacology (01.08.2013)
Published in Biochemical pharmacology (01.08.2013)
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Human CYP2C-mediated stereoselective phenytoin hydroxylation in Japanese: difference in chiral preference of CYP2C9 and CYP2C19
Yasumori, Toshio, Chen, Lai-shun, Li, Qing-hua, Ueda, Masakazu, Tsuzuki, Toshiharu, Goldstein, Joyce A, Kato, Ryuichi, Yamazoe, Yasushi
Published in Biochemical pharmacology (01.06.1999)
Published in Biochemical pharmacology (01.06.1999)
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Antiepileptic Drug–Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator–Activated Receptor α and Peroxisome Proliferator–Activated Receptor γ Coactivator 1 α –Dependent Gene Expression to Increase Blood Triglyceride Levels
Shizu, Ryota, Otsuka, Yuta, Ezaki, Kanako, Ishii, Chizuru, Arakawa, Shingo, Amaike, Yuto, Abe, Taiki, Hosaka, Takuomi, Sasaki, Takamitsu, Kanno, Yuichiro, Miyata, Masaaki, Yamazoe, Yasushi, Yoshinari, Kouichi
Published in Molecular pharmacology (01.11.2020)
Published in Molecular pharmacology (01.11.2020)
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Adenovirus vector-mediated reporter system for in vivo analyses of human CYP3A4 gene activation
Furukawa, Masayuki, Okubo, Takayuki, Ogino, Makoto, Yamazaki, Toru, Shimada, Miki, Nagata, Kiyoshi, Yamazoe, Yasushi
Published in Journal of biochemistry (Tokyo) (01.01.2002)
Published in Journal of biochemistry (Tokyo) (01.01.2002)
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Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[ a]anthracene-induced developmental toxicity
Miyata, Masaaki, Motoki, Kazuko, Tamura, Etsuko, Furukawa, Masayuki, Gonzalez, Frank J., Yamazoe, Yasushi
Published in Biochemical pharmacology (15.03.2002)
Published in Biochemical pharmacology (15.03.2002)
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A Summary Report of FSCJ Workshop “Future Challenges and Opportunities in Developing Methodologies for Improved Human Risk Assessments”
Tachibana, Kaoruko, Kass, George E.N., Ono, Atsushi, Yamada, Takashi, Tong, Weida, Doerge, Daniel R., Yamazoe, Yasushi
Published in Food Safety (2019)
Published in Food Safety (2019)
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Construction of a System that Simultaneously Evaluates CYP1A1 and CYP1A2 Induction in a Stable Human-derived Cell Line using a Dual Reporter Plasmid
Wataru SATO, Hiroyuki SUZUKI, Takamitsu SASAKI, Takeshi KUMAGAI, Shuhei SAKAGUCHI, Michinao MIZUGAKI, Shinichi MIYAIRI, Yasushi YAMAZOE, Kiyoshi NAGATA
Published in DRUG METABOLISM AND PHARMACOKINETICS (2010)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (2010)
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Role of Human Hepatocyte Nuclear Factor 4α in the Expression of Drug-Metabolizing Enzymes and Transporters in Human Hepatocytes Assessed by Use of Small Interfering RNA
Yoshiteru KAMIYAMA, Tsutomu MATSUBARA, Kouichi YOSHINARI, Kiyoshi NAGATA, Hidetaka KAMIMURA, Yasushi YAMAZOE
Published in DRUG METABOLISM AND PHARMACOKINETICS (2007)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (2007)
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Metabolism of N,N-Dipropyl-2-[4-Methoxy-3-(2-Phenyl-Ethoxy)-Phenyl]-Ethyl-Amine-Monohydrochloride (NE-100), A Novel Sigma Ligand: Contribution of Cytochrome P450 Forms Involved in the Formation of Individual Metabolites in Human Liver and Small Intestine
Yamamoto, Takahito, Hagima, Naoko, Fukasawa, Misako, Yamaguchi, Jun-ichi, Nakamura, Masato, Kohno, Yoshiro, Nagata, Kiyoshi, Yamazoe, Yasushi
Published in Drug metabolism and pharmacokinetics (2003)
Published in Drug metabolism and pharmacokinetics (2003)
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Structure and Expression of the Rat CYP3A1 Gene: Isolation of the Gene (P450/6βB)and Characterization of the Recombinant Protein
Nagata, Kiyoshi, Ogino, Makoto, Shimada, Miki, Miyata, Masaaki, Gonzalez, Frank J., Yamazoe, Yasushi
Published in Archives of biochemistry and biophysics (15.02.1999)
Published in Archives of biochemistry and biophysics (15.02.1999)
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Transactivation of ABCG2 through a novel cis-element in the distal promoter by constitutive androstane receptor but not pregnane X receptor in human hepatocytes
Benoki, Satoshi, Yoshinari, Kouichi, Chikada, Tsubasa, Imai, Jun, Yamazoe, Yasushi
Published in Archives of biochemistry and biophysics (15.01.2012)
Published in Archives of biochemistry and biophysics (15.01.2012)
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