Characterization of the electrocardiogram of microminipig in comparison with that of Clawn miniature swine: impacts of miniaturization of body size on electrocardiographic indices
GOTO, Ai, KAMBAYASHI, Ryuichi, SAITO, Hiroyuki, AKIE, Yasuki, IZUMI-NAKASEKO, Hiroko, TAKEI, Yoshinori, SUGIYAMA, Atsushi
Published in Journal of Veterinary Medical Science (2023)
Published in Journal of Veterinary Medical Science (2023)
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In vivo comparison of dl-sotalol-induced electrocardiographic responses among halothane anesthesia, isoflurane anesthesia with nitrous oxide, and conscious state
Saito, Hiroyuki, Kambayashi, Ryuichi, Hagiwara-Nagasawa, Mihoko, Nunoi, Yoshio, Goto, Ai, Izumi-Nakaseko, Hiroko, Kawai, Shinichi, Takei, Yoshinori, Matsumoto, Akio, Hoshiai, Kiyotaka, Akie, Yasuki, Sugiyama, Atsushi
Published in Journal of pharmacological sciences (01.01.2021)
Published in Journal of pharmacological sciences (01.01.2021)
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In vivo analysis of concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables in dogs
Saito, Hiroyuki, Kambayashi, Ryuichi, Goto, Ai, Hagiwara-Nagasawa, Mihoko, Hoshiai, Kiyotaka, Nunoi, Yoshio, Izumi-Nakaseko, Hiroko, Akie, Yasuki, Takei, Yoshinori, Matsumoto, Akio, Sugiyama, Atsushi
Published in Journal of pharmacological sciences (01.03.2021)
Published in Journal of pharmacological sciences (01.03.2021)
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Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies
Yokoyama, Hirofumi, Nakamura, Yuji, Saito, Hiroyuki, Nagayama, Yukitoshi, Hoshiai, Kiyotaka, Wada, Takeshi, Izumi-Nakaseko, Hiroko, Ando, Kentaro, Akie, Yasuki, Sugiyama, Atsushi
Published in Journal of toxicological sciences (2017)
Published in Journal of toxicological sciences (2017)
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Electropharmacological characterization of microminipigs as a laboratory animal using anti-influenza virus drug oseltamivir
Lubna, Nur Jaharat, Nakamura, Yuji, Hagiwara-Nagasawa, Mihoko, Goto, Ai, Chiba, Koki, Kitta, Kumiko, Izumi-Nakaseko, Hiroko, Ando, Kentaro, Naito, Atsuhiko T., Akie, Yasuki, Sugiyama, Atsushi
Published in Journal of toxicological sciences (01.01.2018)
Published in Journal of toxicological sciences (01.01.2018)
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Journal Article
Use of microminipigs for unveiling unknown mechanisms of azithromycin-induced cardiovascular death
Goto, Ai, Hagiwara-Nagasawa, Mihoko, Izumi-Nakaseko, Hiroko, Kitta, Kumiko, Hoshiai, Kiyotaka, Chiba, Koki, Ando, Kentaro, Akie, Yasuki, Naito, Atsuhiko T., Sugiyama, Atsushi
Published in Journal of pharmacological sciences (01.11.2018)
Published in Journal of pharmacological sciences (01.11.2018)
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Microminipig, a Non-rodent Experimental Animal Optimized for Life Science Research: In Vivo Proarrhythmia Models of Drug-Induced Long QT Syndrome: Development of Chronic Atrioventricular Block Model of Microminipig
Sugiyama, Atsushi, Nakamura, Yuji, Akie, Yasuki, Saito, Hiroyuki, Izumi, Yasukatsu, Yamazaki, Hiroshi, Kaneko, Naoki, Itoh, Katzuhiko
Published in Journal of Pharmacological Sciences (2011)
Published in Journal of Pharmacological Sciences (2011)
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Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs
Ando, Kentaro, Takahara, Akira, Nakamura, Yuji, Wada, Takeshi, Chiba, Koki, Goto, Ai, Lubna, Nur Jaharat, Hagiwara-Nagasawa, Mihoko, Izumi-Nakaseko, Hiroko, Hoshiai, Kiyotaka, Akie, Yasuki, Naito, Atsuhiko T., Sugiyama, Atsushi
Published in Journal of pharmacological sciences (01.02.2018)
Published in Journal of pharmacological sciences (01.02.2018)
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QT PRODACT: In Vivo QT Assay in Anesthetized Dog for Detecting the Potential for QT Interval Prolongation by Human Pharmaceuticals
Tashibu, Hiroyuki, Miyazaki, Hiroyasu, Aoki, Kumiko, Akie, Yasuki, Yamamoto, Keiji
Published in Journal of Pharmacological Sciences (01.01.2005)
Published in Journal of Pharmacological Sciences (01.01.2005)
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Twenty-six-week oral toxicity of diheptyl phthalate with special emphasis on its induction of liver proliferative lesions in male F344 rats
Nakane, Fumiyuki, Kunieda, Masaki, Shimizu, Shigekazu, Kobayashi, Yoshihiko, Akane, Hirotoshi, Akie, Yasuki, Saito, Akemi, Noguchi, Masayoshi, Kadota, Toshihito, Mitsumori, Kunitoshi
Published in Journal of toxicological sciences (2012)
Published in Journal of toxicological sciences (2012)
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S1E-7-3 Total assessment of drug-induced ECG changes by Microminipigs
Atsushi Sugiyama, Yuji Nakamura, Ken Kitahara, Hiroyuki Saito, Yasuki Akie
Published in Journal of Pharmacological Sciences (2012)
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Published in Journal of Pharmacological Sciences (2012)
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O3H-33-5 Predictability of clinical cardiovascular drug responses by halothane-anesthetized Microminipig
Hirofumi Yokoyama, Yuji Nakamura, Yasuki Akie, Hiroyuki Saito, Yukitoshi Nagayama, Kiyotaka Hoshiai, Atsushi Sugiyama
Published in Journal of Pharmacological Sciences (15.03.2013)
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Published in Journal of Pharmacological Sciences (15.03.2013)
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P2-13-7 Long term exposure to cigarette smoke solution induced the airway remodeling and pulmonary emphysema in guinea pigs
Yuki Nishimoto, Jun-ichi Fuchikami, Maki Takahashi, Yoshitomo Morozumi, Yasuki Akie, Akemi Saito, Hisatoshi Sugiura, Masakazu Ichinose, Yoshiki Sakai
Published in Journal of Pharmacological Sciences (2012)
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Published in Journal of Pharmacological Sciences (2012)
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