A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates
Ding, Huiping, Kiguchi, Norikazu, Yasuda, Dennis, Daga, Pankaj R, Polgar, Willma E, Lu, James J, Czoty, Paul W, Kishioka, Shiroh, Zaveri, Nurulain T, Ko, Mei-Chuan
Published in Science translational medicine (29.08.2018)
Published in Science translational medicine (29.08.2018)
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Synthesis and biological activity of new pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase
Kennedy-Smith, Joshua J., Arora, Nidhi, Billedeau, J. Roland, Fretland, Jennifer, Hang, Julie Q., Heilek, Gabrielle M., Harris, Seth F., Hirschfeld, Donald, Javanbakht, Hassan, Li, Yu, Liang, Weiling, Roetz, Ralf, Smith, Mark, Su, Guoping, Suh, Judy M., Villaseñor, Armando G., Wu, Jeffrey, Yasuda, Dennis, Klumpp, Klaus, Sweeney, Zachary K.
Published in MedChemComm (01.07.2010)
Published in MedChemComm (01.07.2010)
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Structure-Based SAR in the Design of Selective or Bifunctional Nociceptin (NOP) Receptor Agonists
Meyer, Michael E., Doshi, Arpit, Yasuda, Dennis, Zaveri, Nurulain T.
Published in The AAPS journal (11.05.2021)
Published in The AAPS journal (11.05.2021)
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Discovery and Structure–Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson’s Disease Models
Kamakolanu, Uma Gayathri, Meyer, Michael E, Yasuda, Dennis, Polgar, Willma E, Marti, Matteo, Mercatelli, Daniela, Pisanò, Clarissa Anna, Brugnoli, Alberto, Morari, Michele, Zaveri, Nurulain T
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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The α3β4 nAChR partial agonist AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats
Yuan, Menglu, Malagon, Ariana M., Yasuda, Dennis, Belluzzi, James D., Leslie, Frances M., Zaveri, Nurulain T.
Published in Behavioural brain research (30.08.2017)
Published in Behavioural brain research (30.08.2017)
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High affinity α3β4 nicotinic acetylcholine receptor ligands AT-1001 and AT-1012 attenuate cocaine-induced conditioned place preference and behavioral sensitization in mice
Khroyan, Taline V., Yasuda, Dennis, Toll, Lawrence, Polgar, Willma E., Zaveri, Nurulain T.
Published in Biochemical pharmacology (15.10.2015)
Published in Biochemical pharmacology (15.10.2015)
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AT‐1001: a high‐affinity α3β4 nAChR ligand with novel nicotine‐suppressive pharmacology
Cippitelli, Andrea, Wu, Jinhua, Gaiolini, Kelly A, Mercatelli, Daniela, Schoch, Jennifer, Gorman, Michelle, Ramirez, Alejandra, Ciccocioppo, Roberto, Khroyan, Taline V, Yasuda, Dennis, Zaveri, Nurulain T, Pascual, Conrado, Xie, Xinmin (Simon), Toll, Lawrence
Published in British journal of pharmacology (01.04.2015)
Published in British journal of pharmacology (01.04.2015)
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AT-1001: a high-affinity alpha 3 beta 4 nAChR ligand with novel nicotine-suppressive pharmacology
Cippitelli, Andrea, Wu, Jinhua, Gaiolini, Kelly A, Mercatelli, Daniela, Schoch, Jennifer, Gorman, Michelle, Ramirez, Alejandra, Ciccocioppo, Roberto, Khroyan, Taline V, Yasuda, Dennis, Zaveri, Nurulain T, Pascual, Conrado, Xie, Xinmin, Toll, Lawrence
Published in British journal of pharmacology (01.04.2015)
Published in British journal of pharmacology (01.04.2015)
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In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations
Ferrari, Federica, Cerlesi, Maria Camilla, Malfacini, Davide, Asth, Laila, Gavioli, Elaine C., Journigan, Blair V., Kamakolanu, Uma Gayathri, Meyer, Michael E., Yasuda, Dennis, Polgar, Willma E., Rizzi, Anna, Guerrini, Remo, Ruzza, Chiara, Zaveri, Nurulain T., Calo, Girolamo
Published in European journal of pharmacology (15.12.2016)
Published in European journal of pharmacology (15.12.2016)
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Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption
Kallupi, Marsida, Shen, Qianwei, Guglielmo, Giordano, Yasuda, Dennis, Journigan, V. Blair, Zaveri, Nurulain T., Ciccocioppo, Roberto
Published in Addiction biology (01.03.2018)
Published in Addiction biology (01.03.2018)
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AT-1001: a high-affinity [alpha]3[beta]4 nAChR ligand with novel nicotine-suppressive pharmacology
Cippitelli, Andrea, Wu, Jinhua, Gaiolini, Kelly A, Mercatelli, Daniela, Schoch, Jennifer, Gorman, Michelle, Ramirez, Alejandra, Ciccocioppo, Roberto, Khroyan, Taline V, Yasuda, Dennis, Zaveri, Nurulain T, Pascual, Conrado, Xie, Xinmin (Simon), Toll, Lawrence
Published in British journal of pharmacology (01.04.2015)
Published in British journal of pharmacology (01.04.2015)
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