Glutathione transferase P1 is modified by palmitate
Marensi, Vanessa, Yap, Megan C, Ji, Yuhuan, Lin, Cheng, Berthiaume, Luc G, Leslie, Elaine M
Published in PloS one (13.09.2024)
Published in PloS one (13.09.2024)
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Journal Article
Palmitoylated TMX and calnexin target to the mitochondria-associated membrane
Lynes, Emily M, Bui, Michael, Yap, Megan C, Benson, Matthew D, Schneider, Bobbie, Ellgaard, Lars, Berthiaume, Luc G, Simmen, Thomas
Published in The EMBO journal (18.01.2012)
Published in The EMBO journal (18.01.2012)
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Journal Article
Targeting N-myristoylation for therapy of B-cell lymphomas
Beauchamp, Erwan, Yap, Megan C., Iyer, Aishwarya, Perinpanayagam, Maneka A., Gamma, Jay M., Vincent, Krista M., Lakshmanan, Manikandan, Raju, Anandhkumar, Tergaonkar, Vinay, Tan, Soo Yong, Lim, Soon Thye, Dong, Wei-Feng, Postovit, Lynne M., Read, Kevin D., Gray, David W., Wyatt, Paul G., Mackey, John R., Berthiaume, Luc G.
Published in Nature communications (22.10.2020)
Published in Nature communications (22.10.2020)
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Journal Article
The ER chaperone calnexin controls mitochondrial positioning and respiration
Gutiérrez, Tomás, Qi, Hong, Yap, Megan C, Tahbaz, Nasser, Milburn, Leanne A, Lucchinetti, Eliana, Lou, Phing-How, Zaugg, Michael, LaPointe, Paul G, Mercier, Pascal, Overduin, Michael, Bischof, Helmut, Burgstaller, Sandra, Malli, Roland, Ballanyi, Klaus, Shuai, Jianwei, Simmen, Thomas
Published in Science signaling (30.06.2020)
Published in Science signaling (30.06.2020)
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Journal Article
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins
Herrera-Cruz, Maria Sol, Yap, Megan C, Tahbaz, Nasser, Phillips, Keelie, Thomas, Laurel, Thomas, Gary, Simmen, Thomas
Published in Biology direct (07.11.2021)
Published in Biology direct (07.11.2021)
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Journal Article
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria
Bassot, Arthur, Chen, Junsheng, Takahashi-Yamashiro, Kei, Yap, Megan C., Gibhardt, Christine Silvia, Le, Giang N.T., Hario, Saaya, Nasu, Yusuke, Moore, Jack, Gutiérrez, Tomas, Mina, Lucas, Mast, Heather, Moses, Audric, Bhat, Rakesh, Ballanyi, Klaus, Lemieux, Hélène, Sitia, Roberto, Zito, Ester, Bogeski, Ivan, Campbell, Robert E., Simmen, Thomas
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling
Lynes, Emily M, Raturi, Arun, Shenkman, Marina, Ortiz Sandoval, Carolina, Yap, Megan C, Wu, Jiahui, Janowicz, Aleksandra, Myhill, Nathan, Benson, Matthew D, Campbell, Robert E, Berthiaume, Luc G, Lederkremer, Gerardo Z, Simmen, Thomas
Published in Journal of cell science (01.09.2013)
Published in Journal of cell science (01.09.2013)
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Journal Article
Astrocytes show increased levels of Ero1α in multiple sclerosis and its experimental autoimmune encephalomyelitis animal model
Samtleben, Samira, Mina, Lucas, Yap, Megan C., Branton, William G., Yousuf, Muhammad Saad, Tenorio, Gustavo, Ballanyi, Klaus, Giuliani, Fabrizio, Kerr, Bradley J., Power, Christopher, Simmen, Thomas
Published in The European journal of neuroscience (01.10.2022)
Published in The European journal of neuroscience (01.10.2022)
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Journal Article
Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signalling and Oxidative Phosphorylation Killing Acute Myeloid Leukemia Cells
Gamma, Jay M, Liu, Qiang, Beauchamp, Erwan, Iyer, Aishwarya, Yap, Megan C, Zak, Zoulika, Ekstrom, Cassidy, Pain, Rony, Kostiuk, Morris A, Mackey, John R, Brandwein, Joseph, Wang, Jean Cy, Berthiaume, Luc G
Published in Molecular cancer therapeutics (09.10.2024)
Published in Molecular cancer therapeutics (09.10.2024)
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Electronic Dietary Intake Assessment (e-DIA): Comparison of a Mobile Phone Digital Entry App for Dietary Data Collection With 24-Hour Dietary Recalls
Rangan, Anna M, O'Connor, Sarah, Giannelli, Valentina, Yap, Megan Lh, Tang, Lie Ming, Roy, Rajshri, Louie, Jimmy Chun Yu, Hebden, Lana, Kay, Judy, Allman-Farinelli, Margaret
Published in JMIR mHealth and uHealth (27.10.2015)
Published in JMIR mHealth and uHealth (27.10.2015)
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Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin
Martin, Dale D O, Heit, Ryan J, Yap, Megan C, Davidson, Michael W, Hayden, Michael R, Berthiaume, Luc G
Published in Human molecular genetics (15.06.2014)
Published in Human molecular genetics (15.06.2014)
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Journal Article
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition
Beauchamp, Erwan, Gamma, Jay M, Cromwell, Christopher R, Moussa, Eman W, Pain, Rony, Kostiuk, Morris A, Acevedo-Morantes, Claudia, Iyer, Aishwarya, Yap, Megan, Vincent, Krista M, Postovit, Lynne M, Julien, Olivier, Hubbard, Basil P, Mackey, John R, Berthiaume, Luc G
Published in Journal of translational medicine (07.05.2024)
Published in Journal of translational medicine (07.05.2024)
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Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry[S]
Yap, Megan C., Kostiuk, Morris A., Martin, Dale D.O., Perinpanayagam, Maneka A., Hak, Pieter G., Siddam, Anjaiah, Majjigapu, Janaki R., Rajaiah, Gurram, Keller, Bernd O., Prescher, Jennifer A., Wu, Peng, Bertozzi, Carolyn R., Falck, John R., Berthiaume, Luc G.
Published in Journal of lipid research (01.06.2010)
Published in Journal of lipid research (01.06.2010)
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Journal Article
P465: N‐MYRISTOYLATION INHIBITION ABROGATES OXIDATIVE PHOSPHORYLATION TO TARGET ACUTE MYELOID LEUKEMIA STEM CELLS
Gamma, Jay, Beauchamp, Erwan, Liu, Qiang, Kostiuk, Morris, Iyer, Aishwarya, Yap, Megan, Zak, Zoulika, Ekstrom, Cassidy, Brandwein, Joseph, Wang, Jean, Mackey, John, Berthiaume, Luc
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases
Perinpanayagam, Maneka A, Beauchamp, Erwan, Martin, Dale D O, Sim, Jacky Y W, Yap, Megan C, Berthiaume, Luc G
Published in The FASEB journal (01.02.2013)
Published in The FASEB journal (01.02.2013)
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Tandem reporter assay for myristoylated proteins post-translationally (TRAMPP) identifies novel substrates for post-translational myristoylation: PKCε, a case study
Martin, Dale D O, Ahpin, Chrisselle Y, Heit, Ryan J, Perinpanayagam, Maneka A, Yap, Megan C, Veldhoen, Richard A, Goping, Ing Swie, Berthiaume, Luc G
Published in The FASEB journal (01.01.2012)
Published in The FASEB journal (01.01.2012)
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Journal Article
Widespread dyspigmentation in a child
Yap, Megan, Ricciardo, Bernadette, Kumarasinghe, Prasad, Iacobelli, Jean, Chen, Jacqueline
Published in Pediatric dermatology (14.08.2024)
Published in Pediatric dermatology (14.08.2024)
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Journal Article
Abstract 2256 Redox enzymes as upstream controllers of endoplasmic reticulum (ER)-mitochondria contact sites (ERMCS)
Simmen, Thomas, Chen, Junsheng, Yap, Megan, Makio, Tadashi, Pascual, Danielle, Marcogliese, Paul
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Metastatic atypical fibroxanthoma: the importance of structured reporting for cutaneous sarcoma-like tumour
Yap, Megan, Harvey, Nathan T., Mesbah Ardakani, Nima, Wood, Benjamin A.
Published in Pathology (01.10.2024)
Published in Pathology (01.10.2024)
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