Pyrrole-imidazole polyamide, a synthetic DNA-binding compound, is effective at increasing levels of wild-type mtDNA in both cybrid cells and MELAS patient-derived fibroblast cells with the MELAS A3243G mutation by a selective promotion of wild-type replication
Yano, Takamitsu, Takeuchi-Tomita, Nono, Ueda, Takuya, Haas, Richard H.
Published in Mitochondrion (01.11.2013)
Published in Mitochondrion (01.11.2013)
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Journal Article
Loss of mutant mitochondrial DNA harboring the MELAS A3243G mutation in human cybrid cells after cell-cell fusion with normal tissue-derived fibroblast cells
Yano, Takamitsu, Tanaka, Masashi, Fukuda, Noboru, Ueda, Takuya, Nagase, Hiroki
Published in International journal of molecular medicine (01.01.2010)
Published in International journal of molecular medicine (01.01.2010)
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Journal Article